The framework reads markup. Price is trending higher with momentum. The crowd has caught on and buyers are in control. Price has moved down 0.0% since our last review. Ethical screening: FAIL. This security does not pass our values-based screening criteria. The risk-adjusted return profile shows good risk-adjusted returns. Our composite framework grades it B, carrying a low risk profile. Technically it is holding around 13% above its long-term trend line with momentum reading bullish. Over the past year the shares are up 55%. Our forward projection puts the odds of a 10% gain over the next month near 32%. The street (19 analysts) rates it strong buy, with a mean price target of $145.
Nuvalent, Inc.
NUVL · Nasdaq · USD · Market cap $9.8B · 234 employees
Nuvalent, Inc., a clinical-stage biopharmaceutical company, engages in the development of therapies for patients with cancer.
FAIL · Does not pass the screenScreen close, 2026-10-01 · not a live quote
Last reviewed 5 days ago
Screened 2026-10-01 · the tape above runs as of 19:04 UTC · two dates, stated on purpose · verdict and workings shown in full · never trimmed
What this means: price 123.96 against the desk's fair-value range, base estimate 124.00, over the last year.
- Trend Markup
- Insiders no filings inside 60 days, left as found
- Positioning no disclosures inside 60 days, left as found
- Options no verdict drawn today, left as found
- Ethical does not pass the values gate
Our analytic regime reads on this name, dated and marked against the screened price. Small sample per name, and separate from the daily-framework accuracy on the Track Record page.
This name holds its markup label.
Nuvalent, Inc. holds its Markup at $123.96. The statistical read favours the sellers, held for 97 days.
| Phase | Markup |
| Quantitative state | The statistical read favours the sellers, held for 97 days |
| Price at the screen | $123.96 |
| Valuation | N/A trailing · -30.85 forward price to earnings |
| Values screen | FAIL · score 70.0 |
| Beta | 1.14 |
Five Screens, Shown in Full
Does not pass. Interest-bearing securities
| Test | Figure | Limit | What it means | Status |
|---|---|---|---|---|
| Business activity | Permissible | Core business clean | Its core business isn't built on prohibited lines: no gambling, alcohol, tobacco, weapons, or interest-based lending. | Pass |
| Debt load | Excluded | Below 33% | Interest-bearing debt is of its assets, above the one-third ceiling the screen allows. | Fail |
| Interest-bearing cash | 78.59% | Below 33% | Interest-bearing cash and securities are 78.6% of assets, above the one-third limit. | Fail |
| Receivables | 18.53% | Below 49% | Money owed to the company is 18.5% of assets, under the 49% limit. | Pass |
| Revenue purity | Excluded | Below 5% | of revenue comes from non-compliant sources, over the 5% line. | Fail |
Five checks adapted from AAOIFI screening standards: business activity plus four balance-sheet ratios. All five must pass for ethical clearance. Every figure is arithmetic on public accounts, not judgement.
The Ethical ReadWhy It Falls Short, in Plain English
Nuvalent,'s business is fine, but its cash and interest-bearing securities are about 79% of its assets, well over the ~33% line, so it does not pass on the financial screens.
Read as at 2026-10-04. It updates when the underlying figures move, and past reads are kept below.
What the Numbers Say It Is WorthThe Fair Value Range
Fair value range in USD, drawn from the 2026-10-01 screen. The gold marker is the market price at the same screen. A 0.0% margin of safety to the base estimate.
Reading the gap · Our model and the Street both land near the screened price: fairly valued, with no strong edge either way.
Price History & ProjectionsWhere it has been, where the models see it going. History from market close data; projection points are our fair-value estimates and third-party analyst targets, dated to the 2026-10-01 screen.
Fair value and rating are our own model estimates; the Street's range reflects third-party analyst estimates. Analysis, not advice.
The Business, in Plain WordsClinical stage cancer drug bets rarely pay off
A small lab team in Boston is racing to outsmart lung cancer mutations that keep dodging existing pills. Nuvalent sits at that early, all-or-nothing stage where one successful trial can lift everything and one setback wipes the slate clean.
We pass. The shares already sit at our fair value with no margin of safety, the company burns cash, posts zero profit and a deeply negative return on equity, and our ethical screen lacks enough data to clear it. Nine analysts simply call it a hold.
The real risk is the usual biotech cliff: trial failure, fresh dilution, or a long wait for any revenue. Analysis, not advice.
| Forward P/E | -30.9x |
| EPS, trailing | -6.06 |
| EPS, forward | -4.22 |
| Profit margin | 0.0%currently unprofitable |
| Return on equity | -41.2%not currently earning a positive return on equity |
| FCF yield | -1.84% |
| Current ratio | 16.14comfortably covers its short-term bills |
| Beta | 1.14moves a little more than the market |
| Short interest, float | 0.06% |
| 52-week range | 71.13 - 123.99 |
| Market cap | $9.8B |
| Employees | 234 |
The risks · The things to watch: as a biotechnology name, trial and regulatory outcomes can move it sharply either way.
Plain-English interpretation of our own screen data. Analysis, not advice.
Where & How to TradeNUVL trades on Nasdaq. As a listed security it is accessible through almost any international broker offering its home market. New to this, or investing from abroad? Our guide to accessing global markets covers brokers, currencies and the practical steps.
Every Entry, As Written
The framework has shifted from accumulation to markup since the last review. Price is trending higher with momentum. The crowd has caught on and buyers are in control. Price has moved down 0.0% since our last review. Ethical screening: FAIL. This security does not pass our values-based screening criteria. The risk-adjusted return profile shows good risk-adjusted returns. Our composite framework grades it B, carrying a low risk profile. Technically it is holding around 13% above its long-term trend line with momentum reading bullish. Over the past year the shares are up 55%. Our forward projection puts the odds of a 10% gain over the next month near 32%. The street (19 analysts) rates it strong buy, with a mean price target of $145.
The framework reads accumulation. Smart money appears to be quietly building positions. This typically precedes a markup phase. Price has moved up 0.6% since our last review. Ethical screening: FAIL. This security does not pass our values-based screening criteria. The risk-adjusted return profile shows good risk-adjusted returns. Our composite framework grades it B, carrying a low risk profile. Technically it is holding around 13% above its long-term trend line with momentum reading bullish. Over the past year the shares are up 55%. Our forward projection puts the odds of a 10% gain over the next month near 32%. The street (19 analysts) rates it strong buy, with a mean price target of $145.
The framework reads accumulation. Smart money appears to be quietly building positions. This typically precedes a markup phase. Price has moved down 0.0% since our last review. Ethical screening: FAIL. This security does not pass our values-based screening criteria. The risk-adjusted return profile shows good risk-adjusted returns. Our composite framework grades it B, carrying a low risk profile. Technically it is holding around 13% above its long-term trend line with momentum reading bullish. Over the past year the shares are up 55%. Our forward projection puts the odds of a 10% gain over the next month near 32%. The street (19 analysts) rates it strong buy, with a mean price target of $145.
The framework reads accumulation. Smart money appears to be quietly building positions. This typically precedes a markup phase. Price has moved down 0.0% since our last review. Ethical screening: FAIL. This security does not pass our values-based screening criteria. The risk-adjusted return profile shows good risk-adjusted returns.
The framework reads accumulation. Smart money appears to be quietly building positions. This typically precedes a markup phase. Ethical screening: FAIL. This security does not pass our values-based screening criteria. The risk-adjusted return profile shows good risk-adjusted returns.
Each entry above was written on its date, before the outcome. A journal you can prune is not a journal.
- Health Care Roundup: Market Talk The Wall Street Journal · 4 Aug 2026
- GSK PLC (GSK) (Q2 2026) Earnings Call Highlights: Strong Sales Growth and Accelerated Pipeline ... GuruFocus.com · 30 Jul 2026
- GSK Q2 Earnings Call Highlights MarketBeat · 28 Jul 2026
- GSK secures first lung cancer approval, validating $10.6bn Nuvalent bet Pharmaceutical Technology · 23 Jul 2026
- GSK lung cancer drug gets speedy approval following $10.6B deal BioPharma Dive · 22 Jul 2026
Headlines from third-party outlets, linked for reference: not our reporting, not advice.
Screened names in the same industry · explore each on its own page.
| Period | Price then | Price return | Divs per share | $1,000 became | Total return |
|---|---|---|---|---|---|
| 1 month | $104.55 | +17.8% | · | $1,178 | +17.8% |
| 2 months | $102.74 | +19.9% | · | $1,199 | +19.9% |
| 3 months | $98.00 | +25.7% | · | $1,257 | +25.7% |
| 6 months | $105.91 | +16.3% | · | $1,163 | +16.3% |
| 1 year | $79.46 | +55.1% | · | $1,551 | +55.1% |
| 2 years | $80.06 | +53.9% | · | $1,539 | +53.9% |
| 3 years | $41.82 | +194.6% | · | $2,946 | +194.6% |
Historical returns from market close data. Past performance does not guarantee future results.
This entry now belongs to the ledger. Whatever NUVL does next, these words stay.
Thirteen thousand names carry this page. One desk keeps them honest.
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Join the deskScreening is research, not a fatwa and not financial advice. Figures are drawn from public accounts at the screen date shown. Always manage your risk.