APGE
Apogee Therapeutics, Inc.
Healthcare · Biotechnology · NGM
$77.75
Close 2026-05-28
✗ NOT SCREENED

UNKNOWN MOAT
MODERATE
Data Confidence: 71%
Some financial metrics pending
Market Cap
$5.9B
Trailing P/E
Forward P/E
-15.01
Rev Growth
Profit Margin
0.0%
ROE
-28.5%
Analyst Target
$120.00
Recommendation
STRONG BUY
About Apogee Therapeutics, Inc.

Apogee Therapeutics, Inc., a clinical stage biotechnology company, develops novel biologics for the treatment of atopic dermatitis, asthma, eosinophilic esophagitis, chronic obstructive pulmonary disease, and other inflammatory and immunology indications in the United States. The company develops Zumilokibart (APG777), a subcutaneous (SQ) extended half-life monoclonal antibody (mAb) for the treatment of atopic dermatitis, which is in phase 2 clinical trials; and for the treatment of asthma and eosinophilic esophagitis which is in phase 1 clinical trial. It also develops APG279 which is in phase 1 clinical trial for the treatment of atopic dermatitis; APG273 which is in phase 1 clinical trial for the treatment of asthma and chronic obstructive pulmonary disease; and APG808, an SQ extended half-life mAb targeting IL-4Ra for the treatment of Type 2 allergic diseases. Apogee Therapeutics, Inc. was incorporated in 2022 and is headquartered in Waltham, Massachusetts.

Ethical Screen
Business ActivityPASS
Debt RatioN/A
Cash RatioN/A
Receivables RatioN/A
Revenue RatioN/A
OverallINSUFFICIENT DATA
Score Ethical: 50.0
Score Valuation: 33.0
Score Quality: 21.2
Score Combined: 30.2

Full Analysis

Opportunity scores, earnings history, insider transactions, institutional holders, analyst consensus, and more.

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Opportunity Scores
Valuation50.0
Quality12.5
Cash Flow0.0
Moat40.0
Balance Sheet80.8
Debt Purity50.0
Liquid Purity50.0
Rev Purity50.0
Compliance100.0
Tier: WATCH · Score: 38.9 · Rank: #4374
Insider Transactions
No insider transaction data.
Top Institutional Holders
No institutional holder data.
Additional Fundamentals
Enterprise Value
$4.8B
Price/Book
4.61
Beta
0.692
Analysts
16
Total Debt
$8.0M
Rec. Mean
1.42
Short Ratio
14.63
Short % Float
0.2%
Employees
261

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Trade Consideration
The Opportunity
Score 30.2 (P14 — top 86.3% of scored tickers). Unknown Moat. Ethical FAIL. 17 analysts at Strong Buy.
Price: $77.75 | Target: $118.47 (+52%)
Score
30
Moat
Unknown
Conviction
Standard
Upside
+52%
The Fundamentals
Profit Margin0.0%
ROE-28.5%
Forward P/E-15.0
Market Cap$5.9B
Position Sizing Scenarios
Stop: $66.09 (-15%) | Entry: $77.75
SharesCostProfit to TargetR:R
To Consensus ($118.47, 17 analysts)
10$777.50+$407.20 (52%)3.5R
50$3,887.50+$2,036.00 (52%)3.5R
100$7,775.00+$4,072.00 (52%)3.5R
Risk Factors
  • Elevated short interest (14.63 days to cover)
The Verdict
Apogee Therapeutics, Inc. holds a unknown competitive moat.
Quantitative Grade

A single score combining all analytical layers below. A is strongest, D is weakest.

C
Quant Score
42.5
Risk Grade
Layers
7
Risk Profile

How much could this ticker lose on a bad day? These metrics measure worst-case scenarios from historical data.

VaR 95%
-6.0%
worst expected daily loss, 19 in 20 days
CVaR 95%
-9.0%
avg loss on the worst 5% of days
Annual Volatility
Sortino Ratio
0.62
above 1.0 is good
Max Drawdown
-52.9%
Worst Day
Forward Outlook

Based on 10,000 simulated price paths, here is the probability of where this ticker could be in 30, 60, and 90 days.

30d Prob Up
90d Prob Up
Median Return 30d
Liquidity Score
75
Liquidity Grade
LIQUID
Trend & Momentum

What direction is this ticker actually moving, filtered through noise? Is it speeding up or slowing down?

Kalman Trend
Trend Strength
Momentum Signal
HMM Regime
RSI Signal
Technical Signals

Classic chart signals that institutional traders monitor. Golden Cross is bullish, Death Cross is bearish.

MA Crossover
ABOVE_200
Bollinger Position
NEAR_LOWER
Beta
Relative Volume
1.4x
Short Interest
Financial Health

Is this company financially sound? The Z-Score measures bankruptcy risk. The F-Score measures fundamental strength.

Altman Z-Score
below 1.81 = distress zone
Piotroski F-Score
Earnings Beat Rate
Earnings Consistency
Correlations

These tickers tend to move together (positive) or in opposite directions (negative). Useful for portfolio diversification.

Most Correlated
TickerCorrelation
SYRE0.503
ARKG0.469
IWM0.447
CLDX0.439
XNCR0.435
Inverse Correlated
TickerCorrelation
BAES.L-0.150
NCCI.KW-0.144
AGILQ-0.142
SPI.L-0.131
GDWN.L-0.128
Seasonality

Does this ticker have consistent patterns on certain days or months? Historical tendencies, not guarantees.

Best Day
Wednesday
Worst Day
Tuesday
Best Month
Mar
Worst Month
Jan
Fri-Mon Effect
-0.4060191695319097
Momentum Rankings

How does this ticker's recent performance compare to the entire universe? Ranked across 1, 3, 6, and 12-month returns.

1M Return
-8.8%
3M Return
+12.6%
6M Return
+14.7%
12M Return
+111.0%
Momentum Rank
#1180
Momentum Signal
UP

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