The framework has shifted from markdown to accumulation since the last review. Smart money appears to be quietly building positions. This typically precedes a markup phase. Price has moved up 0.4% since our last review. Ethical screening: FAIL. This security does not pass our values-based screening criteria. The risk-adjusted return profile shows excellent risk-adjusted returns. Our composite framework grades it C. Technically it is holding around 18% above its long-term trend line with momentum reading neutral. Over the past year the shares are up 96%. Our forward projection puts the odds of a 10% gain over the next month near 34%. The street (17 analysts) rates it strong buy, with a mean price target of $118. Insiders have been net sellers over the past quarter.
Apogee Therapeutics, Inc.
APGE · Nasdaq · USD · Market cap $10.2B · 261 employees
Apogee Therapeutics, Inc., a clinical stage biotechnology company, develops novel biologics for the treatment of atopic dermatitis, asthma, eosinophilic esophagitis, chronic obstructive pulmonary disease, and other infla…
Not yet scoredAt the last full screen
2026-09-11
Screened 2026-09-11 · the tape above runs as of 22:12 UTC · 11 Sep · two dates, stated on purpose · verdict and workings shown in full · never trimmed
This name holds its accumulation label.
Apogee Therapeutics, Inc. holds its Accumulation at $135.07. The statistical read favours the sellers, held for 35 days.
| Phase | Accumulation |
| Quantitative state | The statistical read favours the sellers, held for 35 days |
| Price at the screen | $135.07 |
| Valuation | N/A trailing · -26.00 forward price to earnings |
| Values screen | Not scored · score 70.0 |
| Beta | 0.33 |
Five Screens, Shown in Full
This security has not been fully scored against the values screen yet.
| Test | Figure | Limit | What it means | Status |
|---|---|---|---|---|
| Business activity | Permissible | Core business clean | Its core business isn't built on prohibited lines: no gambling, alcohol, tobacco, weapons, or interest-based lending. | Pass |
| Debt load | 0.94% | Below 33% | Interest-bearing debt is just 0.9% of its assets, well under the one-third ceiling: it does not run on borrowed money. | Pass |
| Interest-bearing cash | 18.43% | Below 33% | Cash held in interest-bearing accounts and securities is 18.4% of assets, under the one-third limit. | Pass |
| Receivables | 14.67% | Below 49% | Money owed to the company is 14.7% of assets, under the 49% limit. | Pass |
| Revenue purity | Excluded | Below 5% | of revenue comes from non-compliant sources, over the 5% line. | Fail |
Five checks adapted from AAOIFI screening standards: business activity plus four balance-sheet ratios. All five must pass for ethical clearance. Every figure is arithmetic on public accounts, not judgement.
What the Numbers Say It Is WorthThe Fair Value Range
Fair value range in USD, drawn from the 2026-09-11 screen. The gold marker is the market price at the same screen. The price runs 0.1% above the base estimate.
Third-party analyst targets: 5 covering, consensus Hold. The average target sits −0% from the screen price.
Reading the gap · Our model and the Street both land near today's price: fairly valued, with no strong edge either way.
Price History & ProjectionsWhere it has been, where the models see it going. History from market close data; projection points are our fair-value estimates and third-party analyst targets, dated to the 2026-09-11 screen.
Fair value and rating are our own model estimates; the Street's range reflects third-party analyst estimates. Analysis, not advice.
The Business, in Plain WordsClinical Biotech Priced Near Fair Value
Bringing a new biologic through trials feels like funding a long-shot film that may never reach cinemas. Apogee sits at a clinical stage with zero profit margins and a negative return on equity, yet trades almost exactly at the analysts' median target. The thin margin of safety and complete lack of financial ratio data leave little room to build conviction.
We pass because the ethical screen returns insufficient data and the opportunity rating is none. Negative forward earnings and an unknown moat make any assessment speculative rather than analytical. Without clearer numbers the position stays outside our framework.
Clinical failure, repeated capital raises and binary regulatory outcomes remain the dominant risks. Even a successful trial would still need years of cash burn before any revenue appears. Analysis, not advice.
| Forward P/E | -26.0x |
| EPS, trailing | -4.34 |
| EPS, forward | -5.20 |
| Profit margin | 0.0%currently unprofitable |
| Return on equity | -32.5%not currently earning a positive return on equity |
| FCF yield | -1.42% |
| Debt to equity | 0.57moderate, manageable leverage |
| Current ratio | 26.44comfortably covers its short-term bills |
| Beta | 0.33barely tracks the market's swings |
| Short interest, float | 0.07% |
| 52-week range | 35.39 - 135.09 |
| Market cap | $10.2B |
| Employees | 261 |
The risks · The things to watch: as a biotechnology name, trial and regulatory outcomes can move it sharply either way.
Plain-English interpretation of our own screen data. Analysis, not advice.
Where & How to TradeAPGE trades on Nasdaq. As a listed security it is accessible through almost any international broker offering its home market. New to this, or investing from abroad? Our guide to accessing global markets covers brokers, currencies and the practical steps.
Every Entry, As Written
The framework reads markdown. Price is trending lower. Sellers are in control and the prior trend has reversed. Price has moved up 51.7% since our last review. Ethical screening: FAIL. This security does not pass our values-based screening criteria. The risk-adjusted return profile shows good risk-adjusted returns. Our composite framework grades it C. Technically it is holding around 18% above its long-term trend line with momentum reading neutral. Over the past year the shares are up 96%. Our forward projection puts the odds of a 10% gain over the next month near 34%. The street (17 analysts) rates it strong buy, with a mean price target of $118.
The framework reads markdown. Price is trending lower. Sellers are in control and the prior trend has reversed. Price has moved down 0.0% since our last review. Ethical screening: FAIL. This security does not pass our values-based screening criteria. The risk-adjusted return profile shows good risk-adjusted returns. Our composite framework grades it C. Technically it is holding around 18% above its long-term trend line with momentum reading neutral. Over the past year the shares are up 96%. Our forward projection puts the odds of a 10% gain over the next month near 34%. The street (17 analysts) rates it strong buy, with a mean price target of $118.
The framework reads markdown. Price is trending lower. Sellers are in control and the prior trend has reversed. Price has moved down 0.0% since our last review. Ethical screening: FAIL. This security does not pass our values-based screening criteria. The risk-adjusted return profile shows good risk-adjusted returns. Our composite framework grades it C. Technically it is holding around 18% above its long-term trend line with momentum reading neutral. Over the past year the shares are up 96%. Our forward projection puts the odds of a 10% gain over the next month near 34%. The street (17 analysts) rates it strong buy, with a mean price target of $118.
The framework reads markdown. Price is trending lower. Sellers are in control and the prior trend has reversed. Price has moved down 0.0% since our last review. Ethical screening: FAIL. This security does not pass our values-based screening criteria. The risk-adjusted return profile shows good risk-adjusted returns.
The framework reads markdown. Price is trending lower. Sellers are in control and the prior trend has reversed. Ethical screening: FAIL. This security does not pass our values-based screening criteria. The risk-adjusted return profile shows good risk-adjusted returns.
Each entry above was written on its date, before the outcome. A journal you can prune is not a journal.
Screened names in the same industry · explore each on its own page.
| Date | Insider | Title | Type | Shares | Value |
|---|---|---|---|---|---|
| 2026-08-05 | Dambkowski Carl | Chief Medical Officer | S - Sale+OE | 5,500 | $737,935 |
Public filings, recorded as found. The full tape lives at Insider Intelligence.
| Date | Politician | Party | Type | Amount |
|---|---|---|---|---|
| 30 Mar2026 | Alan Armstrong | Republican | buy | 1K–15K |
| 10 Jul2026 | Ro Khanna | Democrat | sell | 1K–15K |
| Period | Price then | Price return | Divs per share | $1,000 became | Total return |
|---|---|---|---|---|---|
| 1 month | $84.60 | -2.5% | · | $975 | -2.5% |
| 2 months | $86.27 | -4.4% | · | $956 | -4.4% |
| 3 months | $73.51 | +12.2% | · | $1,122 | +12.2% |
| 6 months | $76.53 | +7.7% | · | $1,077 | +7.7% |
| 1 year | $42.02 | +96.2% | · | $1,962 | +96.2% |
| 2 years | $43.90 | +87.8% | · | $1,878 | +87.8% |
Historical returns from market close data. Past performance does not guarantee future results.
This entry now belongs to the ledger. Whatever APGE does next, these words stay.
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Join the deskScreening is research, not a fatwa and not financial advice. Figures are drawn from public accounts at the screen date shown. Always manage your risk.