KRYS
Krystal Biotech, Inc.
Healthcare · Biotechnology · NMS
$306.63
Close 2026-05-28
✓ ETHICAL PASS

UNKNOWN MOAT
HIGH
Data Confidence: 100%
Full financial profile available
Market Cap
$9.0B
Trailing P/E
40.99
Forward P/E
30.42
Rev Growth
+31.9%
Profit Margin
53.9%
ROE
19.9%
Analyst Target
$310.00
Recommendation
STRONG BUY
About Krystal Biotech, Inc.

Krystal Biotech, Inc., a commercial-stage biotechnology company, discovers, develops, manufactures, and commercializes genetic medicines to treat diseases with high unmet medical needs in the United States. The company commercializes VYJUVEK (beremagene geperpavec-svdt, or B-VEC) for the treatment of dystrophic epidermolysis bullosa (DEB). It also develops KB803 for ocular complications of dystrophic epidermolysis bullosa; KB801 for neurotrophic keratitis; KB407, which is in Phase 1 clinical trials for treating cystic fibrosis; KB111 for Hailey-Hailey disease; KB707 for solid tumors; KB304 for dynamic wrinkles; KB707 that is in Phase 1/2 clinical trials for the treatment of anti-PD-1 relapsed/refractory; KB408, which is in Phase 1 clinical trials for treating Alpha-1 antitrypsin deficiency; and KB301 that is in Phase 2 clinical trials for treating aesthetic skin conditions, as well as in open label study with ophthalmic B-VEC for treating for ocular complications of deb. Krystal Biotech, Inc. was founded in 2016 and is headquartered in Pittsburgh, Pennsylvania.

Ethical Screen
Business ActivityPASS
Debt RatioN/A
Cash RatioN/A
Receivables RatioN/A
Revenue Ratio (0.00%)PASS
OverallPASS
Score Ethical: 64.7
Score Valuation: 36.5
Score Quality: 84.0
Score Combined: 53.6

Full Analysis

Opportunity scores, earnings history, insider transactions, institutional holders, analyst consensus, and more.

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Opportunity Scores
Valuation45.6
Quality99.8
Cash Flow19.0
Moat40.0
Balance Sheet77.7
Debt Purity50.0
Liquid Purity50.0
Rev Purity100.0
Compliance100.0
Tier: BRONZE · Score: 52.3 · Rank: #1341
Insider Transactions
No insider transaction data.
Top Institutional Holders
No institutional holder data.
Additional Fundamentals
Enterprise Value
$8.3B
Price/Book
7.15
Beta
0.495
Analysts
9
Total Revenue (TTM)
$417.3M
Total Debt
$9.1M
Earnings Growth
+52.5%
Rec. Mean
1.20
Short Ratio
10.23
Short % Float
0.2%
Employees
295

Elite Intelligence

Trade Consideration with position sizing, convergence signals, and risk analysis. Available to Elite members.

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Trade Consideration
The Opportunity
Score 53.6 (P82 — top 18.4% of scored tickers). Unknown Moat. Ethical PASS. 9 analysts at Strong Buy.
Price: $306.63 | Target: $322.78 (+5%)
Score
54
Moat
Unknown
Conviction
Standard
Upside
+5%
The Fundamentals
Revenue Growth+31.9%
Profit Margin53.9%
ROE19.9%
Forward P/E30.4
Market Cap$9.0B
Position Sizing Scenarios
Stop: $260.64 (-15%) | Entry: $306.63
SharesCostProfit to TargetR:R
To Consensus ($322.78, 9 analysts)
10$3,066.30+$161.50 (5%)0.4R
50$15,331.50+$807.50 (5%)0.4R
100$30,663.00+$1,615.00 (5%)0.4R
Risk Factors
  • Elevated short interest (10.23 days to cover)
  • Valuation stretched on forward earnings
The Verdict
Krystal Biotech, Inc. passes all ethical screens, holds a unknown competitive moat, and is growing revenue at +31.9%.
Quantitative Grade

A single score combining all analytical layers below. A is strongest, D is weakest.

B
Quant Score
65.0
Risk Grade
LOW_RISK
Layers
7
Risk Profile

How much could this ticker lose on a bad day? These metrics measure worst-case scenarios from historical data.

VaR 95%
-3.8%
worst expected daily loss, 19 in 20 days
CVaR 95%
-5.7%
avg loss on the worst 5% of days
Annual Volatility
Sortino Ratio
1.13
above 1.0 is good
Max Drawdown
-42.3%
Worst Day
Forward Outlook

Based on 10,000 simulated price paths, here is the probability of where this ticker could be in 30, 60, and 90 days.

30d Prob Up
90d Prob Up
Median Return 30d
Liquidity Score
70
Liquidity Grade
LIQUID
Trend & Momentum

What direction is this ticker actually moving, filtered through noise? Is it speeding up or slowing down?

Kalman Trend
Trend Strength
Momentum Signal
HMM Regime
RSI Signal
Technical Signals

Classic chart signals that institutional traders monitor. Golden Cross is bullish, Death Cross is bearish.

MA Crossover
ABOVE_200
Bollinger Position
UPPER_HALF
Beta
Relative Volume
1.5x
Short Interest
Financial Health

Is this company financially sound? The Z-Score measures bankruptcy risk. The F-Score measures fundamental strength.

Altman Z-Score
below 1.81 = distress zone
Piotroski F-Score
Earnings Beat Rate
Earnings Consistency
Correlations

These tickers tend to move together (positive) or in opposite directions (negative). Useful for portfolio diversification.

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Inverse Correlated
TickerCorrelation
4337.SR-0.153
STO.AX-0.124
WDS.AX-0.119
BAES.L-0.113
4452.T-0.112
Seasonality

Does this ticker have consistent patterns on certain days or months? Historical tendencies, not guarantees.

Best Day
Friday
Worst Day
Tuesday
Best Month
Nov
Worst Month
May
Fri-Mon Effect
0.146310080349021
Momentum Rankings

How does this ticker's recent performance compare to the entire universe? Ranked across 1, 3, 6, and 12-month returns.

1M Return
+15.2%
3M Return
+12.3%
6M Return
+44.4%
12M Return
+145.4%
Momentum Rank
#487
Momentum Signal
STRONG_UP

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