The framework has shifted from accumulation to markdown since the last review. Price is trending lower. Sellers are in control and the prior trend has reversed. Price has moved up 0.7% since our last review. Ethical screening: FAIL. This security does not pass our values-based screening criteria. The risk-adjusted return profile shows good risk-adjusted returns. Our composite framework grades it C. Technically it is momentum reading neutral. Over the past year the shares are up 50%. Our forward projection puts the odds of a 10% gain over the next month near 34%. The street (8 analysts) rates it strong buy, with a mean price target of $42.
Zenas BioPharma, Inc.
ZBIO · Nasdaq · USD · Market cap $2.1B · 167 employees
Zenas BioPharma, Inc., a clinical-stage biopharma company, engages in the development and commercialization of transformative immunology-based therapies.
FAIL · Does not pass the screenScreen close, 2026-09-21 · not a live quote
Last reviewed 14 days ago
Screened 2026-09-21 · the tape above runs as of 11:17 UTC · two dates, stated on purpose · verdict and workings shown in full · never trimmed
What this means: price 32.55 against the desk's fair-value range, base estimate 45.00, over the last year.
- Trend Markdown
- Insiders no filings inside 60 days, left as found
- Positioning no disclosures inside 60 days, left as found
- Options no verdict drawn today, left as found
- Ethical does not pass the values gate
Our analytic regime reads on this name, dated and marked against the screened price. Small sample per name, and separate from the daily-framework accuracy on the Track Record page.
This name holds its markdown label.
Zenas BioPharma, Inc. holds its Markdown at $32.55. Consolidating, no directional conviction, held for 22 days.
| Phase | Markdown · caution |
| Quantitative state | Consolidating, no directional conviction, held for 22 days |
| Price at the screen | $32.55 |
| Valuation | N/A trailing · -6.94 forward price to earnings |
| Values screen | FAIL · score 70.0 |
| Beta | -1.02 |
Five Screens, Shown in Full
Does not pass. Interest-bearing securities
| Test | Figure | Limit | What it means | Status |
|---|---|---|---|---|
| Business activity | Permissible | Core business clean | Its core business isn't built on prohibited lines: no gambling, alcohol, tobacco, weapons, or interest-based lending. | Pass |
| Debt load | 0.35% | Below 33% | Interest-bearing debt is just 0.3% of its assets, well under the one-third ceiling: it does not run on borrowed money. | Pass |
| Interest-bearing cash | 60.62% | Below 33% | Interest-bearing cash and securities are 60.6% of assets, above the one-third limit. | Fail |
| Receivables | 28.84% | Below 49% | Money owed to the company is 28.8% of assets, under the 49% limit. | Pass |
| Revenue purity | 100.00% | Below 5% | 100.0% of revenue comes from non-compliant sources, over the 5% line. | Fail |
Five checks adapted from AAOIFI screening standards: business activity plus four balance-sheet ratios. All five must pass for ethical clearance. Every figure is arithmetic on public accounts, not judgement.
The Ethical ReadWhy It Falls Short, in Plain English
Zenas BioPharma,'s business is fine, but its cash and interest-bearing securities are about 61% of its assets, well over the ~33% line, so it does not pass on the financial screens.
Read as at 2026-10-04. It updates when the underlying figures move, and past reads are kept below.
What the Numbers Say It Is WorthThe Fair Value Range
Fair value range in USD, drawn from the 2026-09-21 screen. The gold marker is the market price at the same screen. A 38.2% margin of safety to the base estimate.
Third-party analyst targets: 8 covering, consensus Strong Buy. The average target sits +38% from the screen price.
Reading the gap · Both our model and the analysts see meaningful upside from here.
Price History & ProjectionsWhere it has been, where the models see it going. History from market close data; projection points are our fair-value estimates and third-party analyst targets, dated to the 2026-09-21 screen.
Fair value and rating are our own model estimates; the Street's range reflects third-party analyst estimates. Analysis, not advice.
The Business, in Plain WordsBiotech bet with no financials to judge
Picture a lab team betting everything on one antibody still in early trials. Zenas BioPharma offers exactly that, a clinical stage immunology programme with zero revenue and no profit margin to show for it. Analysts like the story enough for a strong buy call and a forty four dollar median target, yet our screen returns insufficient data and no opportunity rating at all.
The reported numbers underline the gap. Forward earnings sit at minus thirteen times, return on equity runs at minus one hundred thirty seven percent, and the company has yet to clear the basic financial ratios we check. Without those anchors any margin of safety calculation remains guesswork even when the share price sits well below our internal fair value line.
Risk here is therefore unquantifiable on standard metrics. Currency, dilution and trial failure sit on top of the ethical data shortfall. We pass until the figures arrive. Analysis, not advice.
| Forward P/E | -6.9x |
| EPS, trailing | -9.63 |
| EPS, forward | -4.66 |
| Profit margin | 0.0%currently unprofitable |
| Return on equity | -199.0%not currently earning a positive return on equity |
| FCF yield | -10.04% |
| Debt to equity | 1.21a meaningful debt load worth watching |
| Current ratio | 9.93comfortably covers its short-term bills |
| Beta | -1.02barely tracks the market's swings |
| Short interest, float | 0.26% |
| 52-week range | 13.50 - 44.60 |
| Market cap | $2.1B |
| Employees | 167 |
The risks · The things to watch: as a biotechnology name, trial and regulatory outcomes can move it sharply either way.
Plain-English interpretation of our own screen data. Analysis, not advice.
Where & How to TradeZBIO trades on Nasdaq. As a listed security it is accessible through almost any international broker offering its home market. New to this, or investing from abroad? Our guide to accessing global markets covers brokers, currencies and the practical steps.
Every Entry, As Written
The framework has shifted from markup to accumulation since the last review. Smart money appears to be quietly building positions. This typically precedes a markup phase. Price has moved up 3.3% since our last review. Ethical screening: FAIL. This security does not pass our values-based screening criteria. The risk-adjusted return profile shows good risk-adjusted returns. Our composite framework grades it C. Technically it is momentum reading neutral. Over the past year the shares are up 50%. Our forward projection puts the odds of a 10% gain over the next month near 34%. The street (8 analysts) rates it strong buy, with a mean price target of $42.
The framework has shifted from accumulation to markup since the last review. Price is trending higher with momentum. The crowd has caught on and buyers are in control. Price has moved up 58.0% since our last review. Ethical screening: FAIL. This security does not pass our values-based screening criteria. The risk-adjusted return profile shows good risk-adjusted returns. Our composite framework grades it C. Technically it is momentum reading neutral. Over the past year the shares are up 50%. Our forward projection puts the odds of a 10% gain over the next month near 34%. The street (8 analysts) rates it strong buy, with a mean price target of $42.
The framework reads accumulation. Smart money appears to be quietly building positions. This typically precedes a markup phase. Price has moved down 0.0% since our last review. Ethical screening: FAIL. This security does not pass our values-based screening criteria. The risk-adjusted return profile shows good risk-adjusted returns. Our composite framework grades it C. Technically it is momentum reading neutral. Over the past year the shares are up 50%. Our forward projection puts the odds of a 10% gain over the next month near 34%. The street (8 analysts) rates it strong buy, with a mean price target of $42.
The framework reads accumulation. Smart money appears to be quietly building positions. This typically precedes a markup phase. Price has moved down 0.0% since our last review. Ethical screening: FAIL. This security does not pass our values-based screening criteria. The risk-adjusted return profile shows good risk-adjusted returns.
The framework reads accumulation. Smart money appears to be quietly building positions. This typically precedes a markup phase. Ethical screening: FAIL. This security does not pass our values-based screening criteria. The risk-adjusted return profile shows good risk-adjusted returns.
Each entry above was written on its date, before the outcome. A journal you can prune is not a journal.
- Fortune Brands and 4 More Stocks See Action From Activist Investors Barrons.com · 28 Aug 2026
- Zenas BioPharma Bear Case Overlooks Obexelimab's Commercial Potential, Wedbush Says MT Newswires · 17 Jul 2026
- Zenas BioPharma (ZBIO): Best IPO Stocks with Huge Upside Potential Insider Monkey · 10 Jul 2026
- Zenas BioPharma's CEO Purchased 60,000 Company Shares. Here's a Deeper Look at the Transaction. Motley Fool · 21 Jun 2026
- Exchange-Traded Funds, Equity Futures Mixed Pre-Bell Wednesday Amid Fresh Economic Signals MT Newswires · 3 Jun 2026
Headlines from third-party outlets, linked for reference: not our reporting, not advice.
Screened names in the same industry · explore each on its own page.
| Period | Price then | Price return | Divs per share | $1,000 became | Total return |
|---|---|---|---|---|---|
| 1 month | $20.40 | -12.2% | · | $878 | -12.2% |
| 2 months | $20.44 | -12.4% | · | $876 | -12.4% |
| 3 months | $24.50 | -26.9% | · | $731 | -26.9% |
| 6 months | $40.21 | -55.5% | · | $445 | -55.5% |
| 1 year | $11.94 | +50.0% | · | $1,500 | +50.0% |
Historical returns from market close data. Past performance does not guarantee future results.
This entry now belongs to the ledger. Whatever ZBIO does next, these words stay.
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Join the deskScreening is research, not a fatwa and not financial advice. Figures are drawn from public accounts at the screen date shown. Always manage your risk.