GHRS
GH Research PLC
Healthcare · Biotechnology · NGM
$21.46
Close 2026-05-15
✓ ETHICAL PASS
MODERATE
Data Confidence: 57%
Some financial metrics pending
Market Cap
$1.5B
Trailing P/E
Forward P/E
-11.35
Rev Growth
Profit Margin
0.0%
ROE
-21.0%
Analyst Target
$39.25
Recommendation
STRONG BUY
About GH Research PLC

GH Research PLC, together with its subsidiary, operates a clinical-stage biopharmaceutical company that develops treatments for depression in the United States. The company's lead product candidate is GH001, an inhalable mebufotenin product candidate that is in Phase 2b clinical trial for treating patients with treatment-resistant depression and in Phase 2a clinical trials for treating bipolar II disorder and postpartum depression. It also develops GH002, an intravenous mebufotenin product candidate, which is in phase 1 clinical pharmacology trial in healthy volunteers focusing on psychiatric and neurological disorders. The company was founded in 2018 and is based in Dublin, Ireland.

Opportunity Summary
Passes all ethical screens. Ranks better than 82% of screened stocks.
Ethical Screen
Business ActivityPASS
Debt Ratio (0.00%)PASS
Cash Ratio (0.19%)PASS
Receivables Ratio (0.00%)PASS
Revenue Ratio (0.00%)PASS
OverallPASS
Score Ethical: 92.9
Score Valuation: 33.0
Score Quality: 30.0
Score Combined: 37.1
· Tier: FAIR VALUE

Full Analysis

Opportunity scores, earnings history, insider transactions, institutional holders, analyst consensus, and more.

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Opportunity Scores
Valuation50.0
Quality30.0
Cash Flow50.0
Moat50.0
Balance Sheet100.0
Debt Purity99.9
Liquid Purity43.3
Rev Purity100.0
Compliance83.3
Tier: BRONZE · Score: 52.5 · Rank: #1301
Earnings History (Last 8 Quarters)
DateEPS Est.Reported EPSSurprise %
2026-08-06-0.32Pending--
2026-05-14-0.26-0.31-17.7%
2026-03-05-0.27-0.22+19.4%
2025-11-06-0.23-0.23+2.1%
2025-08-07-0.20-0.15+24.4%
2025-05-08-0.20-0.19+5.0%
2025-02-27-0.22-0.17+24.1%
2024-11-14-0.25-0.23+8.9%
Quarterly Financials
PeriodRevenueNet IncomeEBITDAGross ProfitOp. IncomeEPS
2026-03-31-$19.0M-$18.9M-$18.7M-0.31
2025-12-31-$14.1M-$14.0M-$16.7M
2025-09-30-$14.0M-$13.9M-$16.5M-0.23
2025-06-30-$9.3M-$9.2M-$14.7M-0.15
2025-03-31-$10.8M-$10.7M-$12.8M-0.19
2024-12-31
Insider Transactions
No insider transaction data.
Top Institutional Holders
HolderSharesValue% Held
Lynx1 Capital Management Lp10.8M$238.1M0.2%
BVF Inc.8.7M$191.3M0.1%
RA Capital Management, L.P.7.7M$169.8M0.1%
RTW Investments LP5.9M$131.3M0.1%
FMR, LLC5.1M$113.6M0.1%
Avoro Capital Advisors LLC1.8M$39.8M0.0%
Toronto Dominion Bank1.4M$30.9M0.0%
Troluce Capital Advisors LLC990.5K$21.9M0.0%
Millennium Management Llc937.9K$20.7M0.0%
Jefferies Financial Group Inc.712.3K$15.8M0.0%
Analyst Recommendations
2 Months Ago
3
6
9 analysts
Last Month
3
6
9 analysts
Current
3
6
9 analysts
Strong Buy Buy Hold Sell Strong Sell
Additional Fundamentals
Enterprise Value
$1.1B
Price/Book
5.21
Beta
1.279
Analysts
8
Total Debt
$432.0K
Rec. Mean
1.33
Short Ratio
9.00
Short % Float
0.1%
Employees
73

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Trade Consideration
The Opportunity
Score 37.1 (P36 — top 64.0% of scored tickers). Ethical PASS. 8 analysts at Strong Buy.
Price: $21.46 | Target: $39.50 (+84%)
Score
37
Moat
Conviction
Standard
Upside
+84%
The Fundamentals
ROE-21.0%
Forward P/E-11.4
Market Cap$1.5B
Earnings Track Record
DateEstimateReportedSurprise
2026-08-06$-0.32Pending
2026-05-14$-0.26$-0.31-17.7%
2026-03-05$-0.27$-0.22+19.4%
2025-11-06$-0.23$-0.23+2.1%
2025-08-07$-0.20$-0.15+24.4%
2025-05-08$-0.20$-0.19+5.0%
Position Sizing Scenarios
Stop: $18.24 (-15%) | Entry: $21.46
SharesCostProfit to TargetR:R
To Consensus ($39.50, 8 analysts)
10$214.60+$180.40 (84%)5.6R
50$1,073.00+$902.00 (84%)5.6R
100$2,146.00+$1,804.00 (84%)5.6R
Risk Factors
  • Elevated short interest (9.00 days to cover)
The Verdict
GH Research PLC passes all ethical screens.
Quantitative Grade

A single score combining all analytical layers below. A is strongest, D is weakest.

B
Quant Score
59.8
Risk Grade
Layers
8
Quality: CONSISTENT_BEATER
Risk Profile

How much could this ticker lose on a bad day? These metrics measure worst-case scenarios from historical data.

VaR 95%
-7.6%
worst expected daily loss, 19 in 20 days
CVaR 95%
-11.2%
avg loss on the worst 5% of days
Annual Volatility
Sortino Ratio
0.47
above 1.0 is good
Max Drawdown
-57.5%
Worst Day
Forward Outlook

Based on 10,000 simulated price paths, here is the probability of where this ticker could be in 30, 60, and 90 days.

30d Prob Up
90d Prob Up
Median Return 30d
Liquidity Score
60
Liquidity Grade
LIQUID
Trend & Momentum

What direction is this ticker actually moving, filtered through noise? Is it speeding up or slowing down?

Kalman Trend
Trend Strength
Momentum Signal
HMM Regime
RSI Signal
Technical Signals

Classic chart signals that institutional traders monitor. Golden Cross is bullish, Death Cross is bearish.

MA Crossover
ABOVE_200
Bollinger Position
NEAR_UPPER
Beta
Relative Volume
0.8x
Short Interest
Financial Health

Is this company financially sound? The Z-Score measures bankruptcy risk. The F-Score measures fundamental strength.

Altman Z-Score
below 1.81 = distress zone
Piotroski F-Score
Earnings Beat Rate
87.5%
Earnings Consistency
Correlations

These tickers tend to move together (positive) or in opposite directions (negative). Useful for portfolio diversification.

Most Correlated
TickerCorrelation
ATAI0.342
CMPS0.309
BLSH0.294
ARKG0.293
IVVD0.288
Inverse Correlated
TickerCorrelation
KMEFIC.KW-0.177
NTBLQ-0.176
PNN.L-0.166
SIM-0.146
IQCD.QA-0.132
Seasonality

Does this ticker have consistent patterns on certain days or months? Historical tendencies, not guarantees.

Best Day
Monday
Worst Day
Tuesday
Best Month
Jan
Worst Month
Dec
Fri-Mon Effect
-1.378432396455885
Earnings Drift

After this company beats earnings, does the price keep going up? Drift tracks post-earnings momentum.

Avg Drift After Beat
+0.8%
Beat Drift Positive %
57.1%
Consistency
Momentum Rankings

How does this ticker's recent performance compare to the entire universe? Ranked across 1, 3, 6, and 12-month returns.

1M Return
+14.3%
3M Return
+51.4%
6M Return
+65.5%
12M Return
+105.4%
Momentum Rank
#334
Momentum Signal
STRONG_UP

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