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The Screen · Healthcare · Biotechnology

AnaptysBio, Inc. logoAnaptysBio, Inc.

ANAB · Nasdaq · USD · Market cap $1.4B · 104 employees

AnaptysBio, Inc., a clinical-stage biotechnology company, focuses in delivering immunology therapeutics for autoimmune and inflammatory diseases in the United States.

FAIL · Does not pass the screen
50.50 USD

Price as of 28 Oct 2026Daily close, not a live quote

Screened 2026-10-28 · the tape above runs as of 12:02 UTC · two dates, stated on purpose · verdict and workings shown in full · never trimmed

Key facts today

  • Price50.50 USD at the 28 Oct 2026 close
  • Ethical screenDoes not pass
  • OptionsOpen interest leans slightly to calls (put/call 0.77)
  • Last reviewed28 Oct 2026 (1 days ago)

A summary of the dated readings below, not a live quote and not advice.

PRICE · FAIR-VALUE RANGE1M3M6MYTD1Y3Y5Y
83.6395.50101.00

What this means: price 50.50 against the desk's fair-value range, base estimate 95.50, over the last year.

Current read
Markdown ?
Screened · screened 2026-10-28
  • Trend Markdown
  • Insiders insiders sold, $249,372, latest filing 2026-10-01
  • Positioning no disclosures inside 60 days, left as found
  • Options put/call open interest 0.77, read 2026-10-24
  • Ethical does not pass the values gate
Price50.50 USD
Fair value95.50
Ethical score70.0/100
Our investment reviews on this name
2026-10-02Read Markdown54.92-8.0% to today ✓Accumulation gives way to Markdown first Markdown read since July
2026-08-21Read Accumulation56.98-11.4% to today Markdown gives way to Accumulation with volume flow in agreement
2026-07-02Read Markdown56.07-9.9% to today ✓First review on file: Markdown

Our analytic regime reads on this name, dated and marked against the screened price. Small sample per name, and separate from the daily-framework accuracy on the Track Record page.

The full research record, in depth, below
The Label · The Season, Not the Day

This name holds its markdown label.

AnaptysBio, Inc. holds its Markdown at $50.50. Consolidating, no directional conviction, held for 63 days.

As held on the ledger · 2026-10-28
PhaseMarkdown · caution
Quantitative stateConsolidating, no directional conviction, held for 63 days
Price at the screen$50.50
ValuationN/A trailing · 9.46 forward price to earnings
Values screenFAIL · score 70.0
Beta0.45
The Workings

Five Screens, Shown in Full

Does not pass. Accounts receivable

TestFigureLimitWhat it meansStatus
Business activity Permissible Core business clean Its core business isn't built on prohibited lines: no gambling, alcohol, tobacco, weapons, or interest-based lending. Pass
Debt load 3.87% Below 33% Interest-bearing debt is just 3.9% of its assets, well under the one-third ceiling: it does not run on borrowed money. Pass
Interest-bearing cash 20.15% Below 33% Cash held in interest-bearing accounts and securities is 20.2% of assets, under the one-third limit. Pass
Receivables 74.66% Below 49% Money owed to the company is 74.7% of assets, above the 49% limit. Fail
Revenue purity 5.75% Below 5% 5.8% of revenue comes from non-compliant sources, over the 5% line. Fail

Five checks adapted from AAOIFI screening standards: business activity plus four balance-sheet ratios. All five must pass for ethical clearance. Every figure is arithmetic on public accounts, not judgement.

The Ethical Read

Why It Falls Short, in Plain English

AnaptysBio,'s business is fine, but its receivables are about 75% of its assets, well over the ~49% line, so it does not pass on the financial screens.

Read as at 2026-10-28. It updates when the underlying figures move, and past reads are kept below.

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What the Numbers Say It Is Worth

The Fair Value Range

83.63Conservative95.50Base case101.00Growth case 50.50Price

Fair value range in USD, drawn from the 2026-10-28 screen. The gold marker is the market price at the same screen. A 89.1% margin of safety to the base estimate.

The Street's Range
60.00Street low 79.50Street average 140.00Street high 50.50Price

Third-party analyst targets: 8 covering, consensus Strong Buy. The average target sits +57% from the screen price.

Reading the gap · Both our model and the analysts see meaningful upside from here.

Price History & Projections
$150$76$2TODAY5y agoPROJECTIONStreet high$140.00 +168%Our fair value$95.50 +83%Conservative$83.63 +60%Street avg$79.50 +52%

Where it has been, where the models see it going. History from market close data; projection points are our fair-value estimates and third-party analyst targets, dated to the 2026-10-28 screen.

Fair value and rating are our own model estimates; the Street's range reflects third-party analyst estimates. Analysis, not advice.

The Business, in Plain Words

Clinical stage bets rarely deliver steady returns

A clinical stage drug developer is like backing an untested runner that has yet to finish a lap. AnaptysBio shows revenue already shrinking eight percent, margins at minus twelve percent and return on equity at minus one hundred fifteen percent. Forward earnings sit at eleven times yet the opportunity rating stays at none, so we pass despite the ethical screen clearing.

The modest ten percent gap to fair value and the strong buy chorus from eleven analysts do not offset a business that is still losing cash with no visible moat. Peak earnings here look distant and fragile rather than a bargain entry point.

Trial outcomes remain binary and funding needs can dilute holders quickly in this sector. Analysis, not advice.

The fundamentals · plain-English read
Forward P/E9.5xcheap for a company growing this fast
EPS, trailing-0.96
EPS, forward5.07
Revenue growth+23.5%strong top-line growth
Profit margin247.0%highly profitable on every dollar of sales
Debt to equity25.47heavy leverage: higher risk if revenue softens
Current ratio5.61comfortably covers its short-term bills
Beta0.45barely tracks the market's swings
Short interest, float0.39%
52-week range20.18 - 72.36
Market cap$1.4B
Employees104

The risks · The things to watch: it's a small-cap, so the share price can swing harder than the market; as a biotechnology name, trial and regulatory outcomes can move it sharply either way; it carries a real debt load, which raises the stakes if revenue slips.

Plain-English interpretation of our own screen data. Analysis, not advice.

Where & How to Trade

ANAB trades on Nasdaq. As a listed security it is accessible through almost any international broker offering its home market. New to this, or investing from abroad? Our guide to accessing global markets covers brokers, currencies and the practical steps.

The Dated Journal · Newest First, Never Edited

Every Entry, As Written

2026-10-29 Markdown $50.50 +5.3% Entry 16

The analysis reads markdown. Price is trending lower. Sellers are in control and the prior trend has reversed. Price has moved up 5.3% since our last review. Ethical screening: FAIL. This security does not pass our values-based screening criteria. The risk-adjusted return profile shows excellent risk-adjusted returns. Our composite framework grades it C. Technically it is holding around 7% above its long-term trend line with momentum reading neutral. Over the past year the shares are up 227%. Our forward projection puts the odds of a 10% gain over the next month near 42%. The street (11 analysts) rates it strong buy, with a mean price target of $84. Insiders have been net sellers over the past quarter. It reported earnings in this window, a natural checkpoint for the thesis.

2026-10-28 Markdown $47.94 +0.0% Entry 15

The analysis reads markdown. Price is trending lower. Sellers are in control and the prior trend has reversed. Price has moved down 0.0% since our last review. Ethical screening: FAIL. This security does not pass our values-based screening criteria. The risk-adjusted return profile shows excellent risk-adjusted returns. Our composite framework grades it C. Technically it is holding around 7% above its long-term trend line with momentum reading neutral. Over the past year the shares are up 227%. Our forward projection puts the odds of a 10% gain over the next month near 42%. The street (11 analysts) rates it strong buy, with a mean price target of $84. Insiders have been net sellers over the past quarter. It reported earnings in this window, a natural checkpoint for the thesis.

2026-10-27 Markdown $47.94 +0.0% Entry 14

The analysis reads markdown. Price is trending lower. Sellers are in control and the prior trend has reversed. Price has moved down 0.0% since our last review. Ethical screening: FAIL. This security does not pass our values-based screening criteria. The risk-adjusted return profile shows excellent risk-adjusted returns. Our composite framework grades it C. Technically it is holding around 7% above its long-term trend line with momentum reading neutral. Over the past year the shares are up 227%. Our forward projection puts the odds of a 10% gain over the next month near 42%. The street (11 analysts) rates it strong buy, with a mean price target of $84. Insiders have been net sellers over the past quarter. It reported earnings in this window, a natural checkpoint for the thesis.

2026-10-26 Markdown $47.94 -1.6% Entry 13

The analysis reads markdown. Price is trending lower. Sellers are in control and the prior trend has reversed. Price has moved down 1.6% since our last review. Ethical screening: FAIL. This security does not pass our values-based screening criteria. The risk-adjusted return profile shows excellent risk-adjusted returns. Our composite framework grades it C. Technically it is holding around 7% above its long-term trend line with momentum reading neutral. Over the past year the shares are up 227%. Our forward projection puts the odds of a 10% gain over the next month near 42%. The street (11 analysts) rates it strong buy, with a mean price target of $84. Insiders have been net sellers over the past quarter.

2026-10-19 Markdown $48.71 +6.0% Entry 12

The analysis reads markdown. Price is trending lower. Sellers are in control and the prior trend has reversed. Price has moved up 6.0% since our last review. Ethical screening: FAIL. This security does not pass our values-based screening criteria. The risk-adjusted return profile shows excellent risk-adjusted returns. Our composite framework grades it B. Technically it is holding around 9% above its long-term trend line with momentum reading bearish. Over the past year the shares are up 227%. Our forward projection puts the odds of a 10% gain over the next month near 42%. The street (11 analysts) rates it strong buy, with a mean price target of $84. Insiders have been net sellers over the past quarter.

2026-10-12 Markdown $45.95 -16.3% Entry 11

The analysis reads markdown. Price is trending lower. Sellers are in control and the prior trend has reversed. Price has moved down 16.3% since our last review. Ethical screening: FAIL. This security does not pass our values-based screening criteria. The risk-adjusted return profile shows excellent risk-adjusted returns. Our composite framework grades it C. Technically it is holding around 73% above its long-term trend line with momentum reading oversold. Over the past year the shares are up 227%. Our forward projection puts the odds of a 10% gain over the next month near 42%. The street (11 analysts) rates it strong buy, with a mean price target of $84. Insiders have been net sellers over the past quarter. Since the last review it its quality tier rose to Gold; its composite score rose.

2026-10-02 Markdown · changed $54.92 -4.1% Entry 10

The framework has shifted from accumulation to markdown since the last review. Price is trending lower. Sellers are in control and the prior trend has reversed. Price has moved down 4.1% since our last review. Ethical screening: FAIL. This security does not pass our values-based screening criteria. The risk-adjusted return profile shows excellent risk-adjusted returns. Our composite framework grades it B. Technically it is holding around 73% above its long-term trend line with momentum reading oversold. Over the past year the shares are up 227%. Our forward projection puts the odds of a 10% gain over the next month near 42%. The street (11 analysts) rates it strong buy, with a mean price target of $84. Since the last review it its composite score rose.

2026-09-08 Accumulation $57.29 +0.0% Entry 9

Our analysis reads accumulation. Smart money appears to be quietly building positions. This typically precedes a markup phase. Price has moved down 0.0% since our last review. Ethical screening: FAIL. This security does not pass our values-based screening criteria. The risk-adjusted return profile shows excellent risk-adjusted returns. Our composite framework grades it B. Technically it is holding around 73% above its long-term trend line with momentum reading oversold. Over the past year the shares are up 227%. Our forward projection puts the odds of a 10% gain over the next month near 42%. The street (11 analysts) rates it strong buy, with a mean price target of $84. It reported earnings in this window, a natural checkpoint for the thesis.

2026-09-06 Accumulation $57.29 +0.0% Entry 8

Our analysis reads accumulation. Smart money appears to be quietly building positions. This typically precedes a markup phase. Price has moved down 0.0% since our last review. Ethical screening: FAIL. This security does not pass our values-based screening criteria. The risk-adjusted return profile shows excellent risk-adjusted returns. Our composite framework grades it B. Technically it is holding around 73% above its long-term trend line with momentum reading oversold. Over the past year the shares are up 227%. Our forward projection puts the odds of a 10% gain over the next month near 42%. The street (11 analysts) rates it strong buy, with a mean price target of $84. It reported earnings in this window, a natural checkpoint for the thesis.

2026-09-05 Accumulation $57.29 +0.5% Entry 7

Our analysis reads accumulation. Smart money appears to be quietly building positions. This typically precedes a markup phase. Price has moved up 0.5% since our last review. Ethical screening: FAIL. This security does not pass our values-based screening criteria. The risk-adjusted return profile shows excellent risk-adjusted returns. Our composite framework grades it B. Technically it is holding around 73% above its long-term trend line with momentum reading oversold. Over the past year the shares are up 227%. Our forward projection puts the odds of a 10% gain over the next month near 42%. The street (11 analysts) rates it strong buy, with a mean price target of $84. It reported earnings in this window, a natural checkpoint for the thesis.

Each entry above was written on its date, before the outcome. A journal you can prune is not a journal.

Latest News · What the Market Is Reading on ANAB

Headlines from third-party outlets, linked for reference: not our reporting, not advice.

Related Securities · Others in ANAB's Space

Screened names in the same industry · explore each on its own page.

The Insider Ledger · Form 4 Filings, As Filed
Most recent filings · ANAB
DateInsiderTitleTypeSharesValue
2026-10-01 Renton Hollings Dir S - Sale+OE 5,000 $249,372

Public filings, recorded as found. The full tape lives at Insider Intelligence.

What Holding Actually Paid · Price Plus Dividends
If $1,000 had been placed · historical, not a promise
PeriodPrice thenPrice returnDivs per share$1,000 becameTotal return
1 month $67.92 -23.0% · $770 -23.0%
2 months $46.73 +12.0% · $1,120 +12.0%
3 months $42.53 +23.0% · $1,230 +23.0%
6 months $30.52 +71.4% · $1,714 +71.4%
1 year $15.98 +227.4% · $3,274 +227.4%
2 years $15.74 +232.4% · $3,324 +232.4%
3 years $12.47 +319.7% · $4,197 +319.7%
5 years $16.19 +223.2% · $3,232 +223.2%

Historical returns from market close data. Past performance does not guarantee future results.

The Ledger's Promise

This entry now belongs to the ledger. Whatever ANAB does next, these words stay.

AnaptysBio, Inc. · ANAB · Markdown · $50.50
Recorded 2026-10-28 · before the outcome · scored mechanically

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