The analysis reads markdown. Price is trending lower. Sellers are in control and the prior trend has reversed. Price has moved down 0.0% since our last review. Ethical screening: not fully scored yet. The risk-adjusted return profile shows modest positive risk-adjusted returns. Our composite framework grades it D. Technically it is sitting below its long-term trend line with momentum reading bearish. Our forward projection puts the odds of a 10% gain over the next month near 44%. The street (10 analysts) rates it strong buy, with a mean price target of $38. Insiders have been net sellers over the past quarter.
MapLight Therapeutics, Inc.
MPLT · Nasdaq · USD · Market cap $465M · 133 employees
MapLight Therapeutics, Inc.
Not yet scoredPrice as of 23 Oct 2026Daily close, not a live quoteLast reviewed 6 days ago
Screened 2026-10-23 · the tape above runs as of 02:01 UTC · two dates, stated on purpose · verdict and workings shown in full · never trimmed
Key facts today
- Price7.97 USD at the 23 Oct 2026 close
- Ethical screenNot yet scored
- Last reviewed23 Oct 2026 (6 days ago)
A summary of the dated readings below, not a live quote and not advice.
What this means: price 7.97 against the desk's fair-value range, base estimate 21.80, over the last year.
- Trend Markdown
- Insiders insiders sold, $96,024, latest filing 2026-10-15
- Positioning no disclosures inside 60 days, left as found
- Options no verdict drawn today, left as found
- Ethical screen not yet scored
Our analytic regime reads on this name, dated and marked against the screened price. Small sample per name, and separate from the daily-framework accuracy on the Track Record page.
This name holds its markdown label.
MapLight Therapeutics, Inc. holds its Markdown at $7.97. The statistical read favours the sellers, held for 40 days.
| Phase | Markdown · caution |
| Quantitative state | The statistical read favours the sellers, held for 40 days |
| Price at the screen | $7.97 |
| Valuation | N/A trailing · -3.17 forward price to earnings |
| Values screen | Not scored · score 70.0 |
Five Screens, Shown in Full
This security has not been fully scored against the values screen yet.
| Test | Figure | Limit | What it means | Status |
|---|---|---|---|---|
| Business activity | Permissible | Core business clean | Its core business isn't built on prohibited lines: no gambling, alcohol, tobacco, weapons, or interest-based lending. | Pass |
| Debt load | 1.21% | Below 33% | Interest-bearing debt is just 1.2% of its assets, well under the one-third ceiling: it does not run on borrowed money. | Pass |
| Interest-bearing cash | 30.86% | Below 33% | Cash held in interest-bearing accounts and securities is 30.9% of assets, under the one-third limit. | Pass |
| Receivables | 9.75% | Below 49% | Money owed to the company is 9.7% of assets, under the 49% limit. | Pass |
Five checks adapted from AAOIFI screening standards: business activity plus four balance-sheet ratios. All five must pass for ethical clearance. Every figure is arithmetic on public accounts, not judgement.
The Ethical ReadThe Read, in Plain English
MapLight Therapeutics, clears the business-activity screen and the figures we can measure look clean, but its income-purity figure is still pending, so the verdict is not final yet.
Read as at 2026-10-28. It updates when the underlying figures move, and past reads are kept below.
What the Numbers Say It Is WorthThe Fair Value Range
Fair value range in USD, drawn from the 2026-10-23 screen. The gold marker is the market price at the same screen. A 100.0% margin of safety to the base estimate.
Third-party analyst targets: 13 covering, consensus Strong Buy. The average target sits +276% from the screen price.
Reading the gap · Both our model and the analysts see meaningful upside from here.
Price History & ProjectionsWhere it has been, where the models see it going. History from market close data; projection points are our fair-value estimates and third-party analyst targets, dated to the 2026-10-23 screen.
Fair value and rating are our own model estimates; the Street's range reflects third-party analyst estimates. Analysis, not advice.
The Business, in Plain WordsClinical Biotech With No Profit Track Record
Picture a lab racing to fix serious brain disorders while burning cash every quarter with nothing yet on the market. MapLight sits in that exact spot, a clinical stage name with zero profit margin, an ROE of minus 81 percent and a forward multiple that simply reflects ongoing losses. We pass because the ethical screen has no financial ratio data at all, leaving us unable to judge the business on any normal standard.
Analysts still see upside to around 42 dollars from the current 37.87, yet the opportunity rating sits at none. A pre revenue biotech with an unknown moat offers little to anchor on beyond hope in one pipeline asset. The margin of safety looks thin once you strip away the consensus noise.
Risks run from trial failure and dilution to the simple fact that we cannot clear the basic ethical hurdles here. Currency and sector swings would only add to the uncertainty. Analysis, not advice.
| Forward P/E | -3.2x |
| EPS, trailing | -4.41 |
| EPS, forward | -3.59 |
| Profit margin | 0.0%currently unprofitable |
| Return on equity | -81.0%not currently earning a positive return on equity |
| FCF yield | -18.55% |
| Debt to equity | 1.40a meaningful debt load worth watching |
| Current ratio | 22.91comfortably covers its short-term bills |
| Short interest, float | 0.16% |
| 52-week range | 9.10 - 40.43 |
| Market cap | $465M |
| Employees | 133 |
The risks · The things to watch: it's a small-cap, so the share price can swing harder than the market; as a biotechnology name, trial and regulatory outcomes can move it sharply either way.
Plain-English interpretation of our own screen data. Analysis, not advice.
Where & How to TradeMPLT trades on Nasdaq. As a listed security it is accessible through almost any international broker offering its home market. New to this, or investing from abroad? Our guide to accessing global markets covers brokers, currencies and the practical steps.
Every Entry, As Written
The analysis reads markdown. Price is trending lower. Sellers are in control and the prior trend has reversed. Price has moved down 10.8% since our last review. Ethical screening: FAIL. This security does not pass our values-based screening criteria. The risk-adjusted return profile shows modest positive risk-adjusted returns. Our composite framework grades it D. Technically it is sitting below its long-term trend line with momentum reading oversold. Our forward projection puts the odds of a 10% gain over the next month near 44%. The street (10 analysts) rates it strong buy, with a mean price target of $38. Insiders have been net sellers over the past quarter.
The analysis reads markdown. Price is trending lower. Sellers are in control and the prior trend has reversed. Price has moved down 19.0% since our last review. Ethical screening: FAIL. This security does not pass our values-based screening criteria. The risk-adjusted return profile shows modest positive risk-adjusted returns. Our composite framework grades it C. Technically it is momentum reading neutral. Our forward projection puts the odds of a 10% gain over the next month near 44%. The street (10 analysts) rates it strong buy, with a mean price target of $38.
The framework has shifted from accumulation to markdown since the last review. Price is trending lower. Sellers are in control and the prior trend has reversed. Price has moved down 4.2% since our last review. Ethical screening: FAIL. This security does not pass our values-based screening criteria. The risk-adjusted return profile shows modest positive risk-adjusted returns. Our composite framework grades it B. Technically it is momentum reading neutral. Our forward projection puts the odds of a 10% gain over the next month near 44%. The street (10 analysts) rates it strong buy, with a mean price target of $38.
The framework has shifted from distribution to accumulation since the last review. Smart money appears to be quietly building positions. This typically precedes a markup phase. Price has moved down 69.9% since our last review. Ethical screening: FAIL. This security does not pass our values-based screening criteria. The risk-adjusted return profile shows good risk-adjusted returns. Our composite framework grades it B. Technically it is momentum reading neutral. Our forward projection puts the odds of a 10% gain over the next month near 44%. The street (10 analysts) rates it strong buy, with a mean price target of $38.
The framework has shifted from markdown to distribution since the last review. Smart money appears to be selling into strength. Institutional holders may be rotating out. Price has moved up 36.5% since our last review. Ethical screening: FAIL. This security does not pass our values-based screening criteria. The risk-adjusted return profile shows good risk-adjusted returns. Our composite framework grades it B. Technically it is momentum reading neutral. Our forward projection puts the odds of a 10% gain over the next month near 44%. The street (10 analysts) rates it strong buy, with a mean price target of $38.
Our analysis reads markdown. Price is trending lower. Sellers are in control and the prior trend has reversed. Price has moved down 0.0% since our last review. Ethical screening: FAIL. This security does not pass our values-based screening criteria. The risk-adjusted return profile shows excellent risk-adjusted returns. Our composite framework grades it B. Technically it is momentum reading neutral. Our forward projection puts the odds of a 10% gain over the next month near 44%. The street (10 analysts) rates it strong buy, with a mean price target of $38.
Our analysis reads markdown. Price is trending lower. Sellers are in control and the prior trend has reversed. Price has moved down 0.0% since our last review. Ethical screening: FAIL. This security does not pass our values-based screening criteria. The risk-adjusted return profile shows excellent risk-adjusted returns.
Our analysis reads markdown. Price is trending lower. Sellers are in control and the prior trend has reversed. Ethical screening: FAIL. This security does not pass our values-based screening criteria. The risk-adjusted return profile shows excellent risk-adjusted returns.
Each entry above was written on its date, before the outcome. A journal you can prune is not a journal.
Screened names in the same industry · explore each on its own page.
| Date | Insider | Title | Type | Shares | Value |
|---|---|---|---|---|---|
| 2026-10-15 | Kreitzer Anatol | Chief Discovery Officer | S - Sale | 12,248 | $96,024 |
| 2026-10-15 | Gillis Jonathan | CAO, Interim CFO | S - Sale | 10,167 | $82,149 |
| 2026-10-15 | Lillie James Woodruff | Chief Scientific Officer | S - Sale | 11,513 | $93,025 |
| 2026-10-15 | Hanson Kristopher | GC | S - Sale | 9,020 | $72,882 |
| 2026-10-15 | Foff Erin Pennock | Chief Medical Officer | S - Sale | 15,355 | $124,068 |
| 2026-10-15 | Kroeger Christopher A. | CEO | S - Sale | 73,691 | $595,423 |
Public filings, recorded as found. The full tape lives at Insider Intelligence.
| Period | Price then | Price return | Divs per share | $1,000 became | Total return |
|---|---|---|---|---|---|
| 1 month | $30.09 | -6.7% | · | $933 | -6.7% |
| 2 months | $26.73 | +5.1% | · | $1,051 | +5.1% |
| 3 months | $19.14 | +46.7% | · | $1,467 | +46.7% |
| 6 months | $20.09 | +39.7% | · | $1,397 | +39.7% |
Historical returns from market close data. Past performance does not guarantee future results.
This entry now belongs to the ledger. Whatever MPLT does next, these words stay.
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