STOK
Stoke Therapeutics, Inc.
Healthcare · Biotechnology · NMS
$30.01
Data: 2026-05-28
✓ ETHICAL PASS

Unknown MOAT
HIGH
Data Confidence: 85.7%
Key Metrics

How this company measures up on the fundamentals that matter

Market Cap
$2.0B
Total market value of the company
-10.13
Based on estimated future earnings — lower means cheaper
Rev Growth
-96.1%
Year-over-year revenue change
Profit Margin
0.0%
How much profit the company keeps from each dollar of revenue
-45.6%
Return on equity — how efficiently it uses shareholder money
Analyst Target
$40.00
+33% from current price — median analyst estimate
Recommendation
STRONG_BUY
Consensus view from 10 analysts covering this stock
About Stoke Therapeutics, Inc.

Stoke Therapeutics, Inc. engages in the development of treatments for severe genetic diseases by upregulating protein expression. The company utilizes its proprietary Targeted Augmentation of Nuclear Gene Output (TANGO) approach in developing antisense oligonucleotides (ASOs) to selectively restore protein levels. Its lead product candidates include STK-002, which is in Phase 1 clinical trials for the treatment of autosomal dominant optic atrophy; and Zorevunersen (STK-001), an investigational new medicine for the treatment of Dravet syndrome is being evaluated in phase 3 clinical trials. The company also develops programs focused on various targets, including haploinsufficiency diseases of the central nervous system and eye. It has a license and collaboration with Biogen Inc. for the development and commercialization of zorevunersen medicine for the treatment of Dravet syndrome; and Acadia Pharmaceuticals Inc. for the discovery, development, and commercialization of novel RNA-based medicines for the treatment of genetic neurodevelopmental diseases. The company was formerly known as ASOthera Pharmaceuticals, Inc. and changed its name to Stoke Therapeutics, Inc. in May 2016. Stoke Therapeutics, Inc. was incorporated in 2014 and is headquartered in Bedford, Massachusetts.

https://www.stoketherapeutics.com

Country: United States Employees: 170 Industry: Biotechnology
Ethical Screening

Five compliance checks based on AAOIFI standards — all must pass for ethical clearance

Business Activity
PASS
Core business does not involve prohibited activities
Debt Ratio
0.0% N/A
Debt must be below 33% of total assets
Cash Ratio
0.0% N/A
Interest-bearing cash below 33% of assets
Receivables
0.0% N/A
Receivables below 49% of assets
Revenue Purity
0.0% PASS
Non-compliant revenue below 5% — any excess requires purification
Quantitative Intelligence

Statistical analysis of price behaviour, risk, and market regime — independent of fundamental data

MARKDOWN
Price trending down — defensive positioning
0.957
Good returns relative to risk taken
0.0778
Suggested allocation is meaningful — the edge justifies a position
0.782
Acceptable balance between returns and drawdown risk
Annual Return
51.9%
Historical annualised return based on price data
-66.3%
Largest peak-to-trough decline — the worst it has been
BEAR
Statistical model detects bearish conditions
Days in State
33
How long the current regime has persisted — longer means more stable
Market Data

Trading characteristics and market positioning

1.20
Moves slightly more than the broader market
52W High
$40.22
25% below the year high
52W Low
$9.34
221% above the year low
Avg Volume
710,759
Average daily shares traded — higher means easier to buy and sell
25.9
Days it would take all short sellers to cover — higher means more crowded
Short % Float
21.6%
Very high short interest — potential squeeze candidate
N/A
Annual dividend as a percentage of the share price
$-2.86
Earnings per share over the last 12 months
Financial Health

Balance sheet strength and cash generation — the foundation of long-term value

0.87
Moderate leverage — manageable
8.99
Strong balance sheet — comfortably covers short-term obligations
Quick Ratio
8.57
Like current ratio but excludes inventory — stricter test
Gross Margin
100.0%
Revenue left after cost of goods — higher means pricing power
Operating Margin
-857.6%
Profit from core operations before interest and tax
$-88,685,376
Negative — the business is spending more than it generates
Revenue (TTM)
$32M
Total revenue over the last 12 months
Net Income
$-169,767,008
Loss-making — spending exceeds revenue after all costs
Analyst Coverage
Analysts
10
Target High
$60.00
Target Median
$40.00
Target Low
$35.00
Explore the Ethical Screener View Track Record

Data sourced from public filings and market feeds. Not financial advice. Updated: 2026-05-28

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