The framework has shifted from accumulation to markdown since the last review. Price is trending lower. Sellers are in control and the prior trend has reversed. Price has moved up 1.7% since our last review. Ethical screening: FAIL. This security does not pass our values-based screening criteria. The risk-adjusted return profile shows good risk-adjusted returns. Our composite framework grades it C. Technically it is momentum reading neutral. Over the past year the shares are up 83%. Our forward projection puts the odds of a 10% gain over the next month near 37%. The street (11 analysts) rates it strong buy, with a mean price target of $63. Insiders have been net sellers over the past quarter.
Maze Therapeutics, Inc.
MAZE · Nasdaq · USD · Market cap $1.6B · 141 employees
Maze Therapeutics, Inc., a clinical stage biopharmaceutical company, develops small molecule precision medicines for the treatment of kidney and metabolic diseases in the United States.
Not yet scoredAt the last full screen
2026-08-27
Screened 2026-08-27 · the tape above runs as of 22:12 UTC · 11 Sep · two dates, stated on purpose · verdict and workings shown in full · never trimmed
This name holds its markdown label.
Maze Therapeutics, Inc. holds its Markdown at $28.60. Consolidating, no directional conviction, held for 26 days.
| Phase | Markdown · caution |
| Quantitative state | Consolidating, no directional conviction, held for 26 days |
| Price at the screen | $28.60 |
| Valuation | N/A trailing · -9.01 forward price to earnings |
| Values screen | Not scored · score 70.0 |
Five Screens, Shown in Full
This security has not been fully scored against the values screen yet.
| Test | Figure | Limit | What it means | Status |
|---|---|---|---|---|
| Business activity | Permissible | Core business clean | Its core business isn't built on prohibited lines: no gambling, alcohol, tobacco, weapons, or interest-based lending. | Pass |
| Debt load | 5.87% | Below 33% | Interest-bearing debt is just 5.9% of its assets, well under the one-third ceiling: it does not run on borrowed money. | Pass |
| Interest-bearing cash | 4.56% | Below 33% | Cash held in interest-bearing accounts and securities is 4.6% of assets, under the one-third limit. | Pass |
| Receivables | 47.65% | Below 49% | Money owed to the company is 47.7% of assets, under the 49% limit. | Pass |
| Revenue purity | Excluded | Below 5% | of revenue comes from non-compliant sources, over the 5% line. | Fail |
Five checks adapted from AAOIFI screening standards: business activity plus four balance-sheet ratios. All five must pass for ethical clearance. Every figure is arithmetic on public accounts, not judgement.
What the Numbers Say It Is WorthThe Fair Value Range
Fair value range in USD, drawn from the 2026-08-27 screen. The gold marker is the market price at the same screen. A 92.3% margin of safety to the base estimate.
Third-party analyst targets: 11 covering, consensus Strong Buy. The average target sits +92% from the screen price.
Reading the gap · Both our model and the analysts see meaningful upside from here.
Price History & ProjectionsWhere it has been, where the models see it going. History from market close data; projection points are our fair-value estimates and third-party analyst targets, dated to the 2026-08-27 screen.
Fair value and rating are our own model estimates; the Street's range reflects third-party analyst estimates. Analysis, not advice.
The Business, in Plain WordsEarly kidney drug bets face binary odds
Picture a lab team racing to turn one molecule into a working pill for rare kidney disease before the cash runs out. Maze Therapeutics sits at that exact point, a clinical stage group with no sales, zero profit margin and a return on equity at minus 39 percent. The market prices the shares at roughly half our internal fair value, yet the opportunity rating stays at none because the business has yet to clear the first real proof point.
Forward earnings sit in negative territory and the moat remains unknown, which leaves the entire story resting on clinical data that may still fail. Eleven analysts call it a strong buy with a median target matching our number, but those forecasts assume success that has not been delivered. The ethical screen clears, yet that alone does not create an investable edge when the company burns cash to reach the next trial readout.
Risk sits in the usual biotech pattern of binary outcomes, dilution and long waits for any revenue. A single failed study can erase most of the apparent discount in weeks. Analysis, not advice.
| Forward P/E | -9.0x |
| EPS, trailing | -2.44 |
| EPS, forward | -3.18 |
| Profit margin | 0.0%currently unprofitable |
| Return on equity | -37.3%not currently earning a positive return on equity |
| FCF yield | -4.00% |
| Debt to equity | 0.13minimal debt: a conservative balance sheet |
| Current ratio | 18.31comfortably covers its short-term bills |
| Short interest, float | 0.12% |
| 52-week range | 13.78 - 53.65 |
| Market cap | $1.6B |
| Employees | 141 |
The risks · The things to watch: it's a small-cap, so the share price can swing harder than the market; as a biotechnology name, trial and regulatory outcomes can move it sharply either way.
Plain-English interpretation of our own screen data. Analysis, not advice.
Where & How to TradeMAZE trades on Nasdaq. As a listed security it is accessible through almost any international broker offering its home market. New to this, or investing from abroad? Our guide to accessing global markets covers brokers, currencies and the practical steps.
Every Entry, As Written
The framework reads accumulation. Smart money appears to be quietly building positions. This typically precedes a markup phase. Price has moved up 16.9% since our last review. Ethical screening: FAIL. This security does not pass our values-based screening criteria. The risk-adjusted return profile shows good risk-adjusted returns. Our composite framework grades it C. Technically it is momentum reading neutral. Over the past year the shares are up 83%. Our forward projection puts the odds of a 10% gain over the next month near 37%. The street (11 analysts) rates it strong buy, with a mean price target of $63.
The framework reads accumulation. Smart money appears to be quietly building positions. This typically precedes a markup phase. Price has moved down 0.0% since our last review. Ethical screening: PASS with passing ethical screen. The risk-adjusted return profile shows good risk-adjusted returns. Our composite framework grades it C. Technically it is momentum reading neutral. Over the past year the shares are up 83%. Our forward projection puts the odds of a 10% gain over the next month near 37%. The street (11 analysts) rates it strong buy, with a mean price target of $63.
The framework reads accumulation. Smart money appears to be quietly building positions. This typically precedes a markup phase. Price has moved down 0.0% since our last review. Ethical screening: PASS with passing ethical screen (70). The risk-adjusted return profile shows good risk-adjusted returns.
The framework reads accumulation. Smart money appears to be quietly building positions. This typically precedes a markup phase. Ethical screening: PASS with passing ethical screen (70). The risk-adjusted return profile shows good risk-adjusted returns.
Each entry above was written on its date, before the outcome. A journal you can prune is not a journal.
Screened names in the same industry · explore each on its own page.
| Date | Insider | Title | Type | Shares | Value |
|---|---|---|---|---|---|
| 2026-08-13 | Bernstein Harold | Pres, R, D, CMO | S - Sale+OE | 16,142 | $445,621 |
Public filings, recorded as found. The full tape lives at Insider Intelligence.
| Period | Price then | Price return | Divs per share | $1,000 became | Total return |
|---|---|---|---|---|---|
| 1 month | $25.52 | -7.5% | · | $925 | -7.5% |
| 2 months | $26.69 | -11.5% | · | $885 | -11.5% |
| 3 months | $51.83 | -54.4% | · | $456 | -54.4% |
| 6 months | $39.57 | -40.3% | · | $597 | -40.3% |
| 1 year | $12.87 | +83.5% | · | $1,835 | +83.5% |
Historical returns from market close data. Past performance does not guarantee future results.
This entry now belongs to the ledger. Whatever MAZE does next, these words stay.
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Join the deskScreening is research, not a fatwa and not financial advice. Figures are drawn from public accounts at the screen date shown. Always manage your risk.