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The Screen · Healthcare · Biotechnology

Mineralys Therapeutics, Inc. logoMineralys Therapeutics, Inc.

MLYS · Nasdaq · USD · Market cap $2.1B · 76 employees

Mineralys Therapeutics, Inc., a biopharmaceutical company, develops medicines to target diseases driven by dysregulated aldosterone in the United States.

FAIL · Does not pass the screen
23.63 USD

Screen close, 2026-10-02 · not a live quote
Last reviewed 5 days ago

Screened 2026-10-02 · the tape above runs as of 05:04 UTC · two dates, stated on purpose · verdict and workings shown in full · never trimmed

PRICE · FAIR-VALUE RANGE1M3M6MYTD1Y3Y5Y
30.0047.2647.26

What this means: price 23.63 against the desk's fair-value range, base estimate 47.26, over the last year.

Current read
Distribution ?
Screened · screened 2026-10-02
  • Trend Distribution
  • Insiders insiders sold, $1,909,665, latest filing 2026-09-30
  • Positioning no disclosures inside 60 days, left as found
  • Options no verdict drawn today, left as found
  • Ethical does not pass the values gate
Price23.63 USD
Fair value47.26
Ethical score70.0/100
Our investment reviews on this name
2026-07-02Read Markup23.62+0.0% to today ✓

Our analytic regime reads on this name, dated and marked against the screened price. Small sample per name, and separate from the daily-framework accuracy on the Track Record page.

The full research record, in depth, below
The Label · The Season, Not the Day

This name holds its distribution label.

Mineralys Therapeutics, Inc. holds its Distribution at $23.63. The statistical read favours the sellers, held for 20 days.

As held on the ledger · 2026-10-02
PhaseDistribution · caution
Quantitative stateThe statistical read favours the sellers, held for 20 days
Price at the screen$23.63
ValuationN/A trailing · -9.45 forward price to earnings
Values screenFAIL · score 70.0
Beta0.68
The Workings

Five Screens, Shown in Full

Does not pass. Interest-bearing securities

TestFigureLimitWhat it meansStatus
Business activity Permissible Core business clean Its core business isn't built on prohibited lines: no gambling, alcohol, tobacco, weapons, or interest-based lending. Pass
Debt load Excluded Below 33% Interest-bearing debt is of its assets, above the one-third ceiling the screen allows. Fail
Interest-bearing cash 73.09% Below 33% Interest-bearing cash and securities are 73.1% of assets, above the one-third limit. Fail
Receivables 26.13% Below 49% Money owed to the company is 26.1% of assets, under the 49% limit. Pass
Revenue purity Excluded Below 5% of revenue comes from non-compliant sources, over the 5% line. Fail

Five checks adapted from AAOIFI screening standards: business activity plus four balance-sheet ratios. All five must pass for ethical clearance. Every figure is arithmetic on public accounts, not judgement.

The Ethical Read

Why It Falls Short, in Plain English

Mineralys Therapeutics,'s business is fine, but its cash and interest-bearing securities are about 73% of its assets, well over the ~33% line, so it does not pass on the financial screens.

Read as at 2026-10-07. It updates when the underlying figures move, and past reads are kept below.

What the Numbers Say It Is Worth

The Fair Value Range

30.00Conservative47.26Base case47.26Growth case 23.63Price

Fair value range in USD, drawn from the 2026-10-02 screen. The gold marker is the market price at the same screen. A 100.0% margin of safety to the base estimate.

The Street's Range
30.00Street low 52.00Street average 56.00Street high 23.63Price

Third-party analyst targets: 8 covering, consensus None. The average target sits +120% from the screen price.

Reading the gap · Both our model and the analysts see meaningful upside from here.

Price History & Projections
$59.4$34.8$10.1TODAY3y agoPROJECTIONStreet high$56.00 +135%Street avg$52.00 +118%Our fair value$47.26 +98%Conservative$30.00 +26%

Where it has been, where the models see it going. History from market close data; projection points are our fair-value estimates and third-party analyst targets, dated to the 2026-10-02 screen.

Fair value and rating are our own model estimates; the Street's range reflects third-party analyst estimates. Analysis, not advice.

The Business, in Plain Words

Aldosterone pill story with no financials to back it

Picture a lab racing to fix hormone-driven blood pressure with one new pill. Mineralys sits at that early stage, yet the opportunity rating sits at none and the ethical screen flags insufficient data because basic ratios are missing.

The numbers show a company still burning cash, with a forward multiple at negative 12.9 times, zero profit margin and return on equity at negative 31 percent. Without a moat rating or consistent financial history the market price at 27 dollars versus a 52-dollar fair value offers no clear edge here.

Risks run high around clinical failure, dilution and the lack of any track record on governance or cash discipline. We pass until the data gaps close. Analysis, not advice.

The fundamentals · plain-English read
Forward P/E-9.5x
EPS, trailing-4.20
EPS, forward-2.50
Profit margin0.0%currently unprofitable
Return on equity-80.9%not currently earning a positive return on equity
FCF yield-9.77%
Debt to equity0.18minimal debt: a conservative balance sheet
Current ratio34.46comfortably covers its short-term bills
Beta0.68steadier than the market
Short interest, float0.12%
52-week range22.30 - 47.65
Market cap$2.1B
Employees76

The risks · The things to watch: as a biotechnology name, trial and regulatory outcomes can move it sharply either way.

Plain-English interpretation of our own screen data. Analysis, not advice.

Where & How to Trade

MLYS trades on Nasdaq. As a listed security it is accessible through almost any international broker offering its home market. New to this, or investing from abroad? Our guide to accessing global markets covers brokers, currencies and the practical steps.

The Dated Journal · Newest First, Never Edited

Every Entry, As Written

2026-10-02 Markup $28.31 +9.3% Entry 6

The framework reads markup. Price is trending higher with momentum. The crowd has caught on and buyers are in control. Price has moved up 9.3% since our last review. Ethical screening: FAIL. This security does not pass our values-based screening criteria. The risk-adjusted return profile shows good risk-adjusted returns. Our composite framework grades it B. Technically it is momentum reading neutral. Over the past year the shares are up 49%. Our forward projection puts the odds of a 10% gain over the next month near 38%. The street (8 analysts) rates it strong buy, with a mean price target of $48. Insiders have been net sellers over the past quarter.

2026-09-05 Markup $25.89 -4.4% Entry 5

The framework reads markup. Price is trending higher with momentum. The crowd has caught on and buyers are in control. Price has moved down 4.4% since our last review. Ethical screening: FAIL. This security does not pass our values-based screening criteria. The risk-adjusted return profile shows good risk-adjusted returns. Our composite framework grades it B. Technically it is momentum reading neutral. Over the past year the shares are up 49%. Our forward projection puts the odds of a 10% gain over the next month near 38%. The street (8 analysts) rates it strong buy, with a mean price target of $48.

2026-08-05 Markup $27.09 +14.7% Entry 4

The framework reads markup. Price is trending higher with momentum. The crowd has caught on and buyers are in control. Price has moved up 14.7% since our last review. Ethical screening: FAIL. This security does not pass our values-based screening criteria. The risk-adjusted return profile shows good risk-adjusted returns. Our composite framework grades it B. Technically it is momentum reading neutral. Over the past year the shares are up 49%. Our forward projection puts the odds of a 10% gain over the next month near 38%. The street (8 analysts) rates it strong buy, with a mean price target of $48.

2026-07-18 Markup $23.62 +0.0% Entry 3

The framework reads markup. Price is trending higher with momentum. The crowd has caught on and buyers are in control. Price has moved down 0.0% since our last review. Ethical screening: FAIL. This security does not pass our values-based screening criteria. The risk-adjusted return profile shows good risk-adjusted returns. Our composite framework grades it B. Technically it is momentum reading neutral. Over the past year the shares are up 49%. Our forward projection puts the odds of a 10% gain over the next month near 38%. The street (8 analysts) rates it strong buy, with a mean price target of $48.

2026-07-03 Markup $23.62 +0.0% Entry 2

The framework reads markup. Price is trending higher with momentum. The crowd has caught on and buyers are in control. Price has moved down 0.0% since our last review. Ethical screening: FAIL. This security does not pass our values-based screening criteria. The risk-adjusted return profile shows good risk-adjusted returns.

2026-07-02 Markup $23.62 Entry 1

The framework reads markup. Price is trending higher with momentum. The crowd has caught on and buyers are in control. Ethical screening: FAIL. This security does not pass our values-based screening criteria. The risk-adjusted return profile shows good risk-adjusted returns.

Each entry above was written on its date, before the outcome. A journal you can prune is not a journal.

Latest News · What the Market Is Reading on MLYS

Headlines from third-party outlets, linked for reference: not our reporting, not advice.

Related Securities · Others in MLYS's Space

Screened names in the same industry · explore each on its own page.

The Insider Ledger · Form 4 Filings, As Filed
Most recent filings · MLYS
DateInsiderTitleTypeSharesValue
2026-09-30 Congleton Jon CEO S - Sale 75,000 $1,909,665
2026-09-22 Slingsby Brian Taylor Dir S - Sale 104,320 $3,005,303
2026-09-15 Karydas Daphne Dir S - Sale+OE 3,000 $85,740

Public filings, recorded as found. The full tape lives at Insider Intelligence.

What Holding Actually Paid · Price Plus Dividends
If $1,000 had been placed · historical, not a promise
PeriodPrice thenPrice returnDivs per share$1,000 becameTotal return
1 month $29.73 -19.8% · $802 -19.8%
2 months $26.62 -10.4% · $896 -10.4%
3 months $26.99 -11.7% · $883 -11.7%
6 months $36.05 -33.9% · $661 -33.9%
1 year $16.03 +48.7% · $1,487 +48.7%
2 years $13.50 +76.6% · $1,766 +76.6%
3 years $14.82 +60.9% · $1,609 +60.9%

Historical returns from market close data. Past performance does not guarantee future results.

The Ledger's Promise

This entry now belongs to the ledger. Whatever MLYS does next, these words stay.

Mineralys Therapeutics, Inc. · MLYS · Distribution · $23.63
Recorded 2026-10-02 · before the outcome · scored mechanically

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