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The Screen · Healthcare · Biotechnology

Structure Therapeutics Inc. logoStructure Therapeutics Inc.

GPCR · Nasdaq · USD · Market cap $2.0B · 220 employees

Structure Therapeutics Inc., a clinical stage global biopharmaceutical company, develops and delivers novel oral small molecule therapeutics to treat various chronic diseases with unmet medical needs in the United States.

FAIL · Does not pass the screen
27.67 USD

Screen close, 2026-10-02 · not a live quote

Screened 2026-10-02 · the tape above runs as of 07:26 UTC · two dates, stated on purpose · verdict and workings shown in full · never trimmed

PRICE · FAIR-VALUE RANGE1M3M6MYTD1Y3Y5Y
70.0070.0070.00

What this means: price 27.67 against the desk's fair-value range, base estimate 70.00, over the last year.

Current read
Distribution ?
Screened · screened 2026-10-02
  • Trend Distribution
  • Insiders no filings inside 60 days, left as found
  • Positioning no disclosures inside 60 days, left as found
  • Options no verdict drawn today, left as found
  • Ethical does not pass the values gate
Price27.67 USD
Fair value70.00
Ethical score70.0/100
Our investment reviews on this name
2026-10-02Read Distribution35.00-20.9% to today ✓
2026-08-31Read Accumulation49.35-43.9% to today
2026-07-31Read Markup48.48-42.9% to today
2026-07-02Read Markdown42.93-35.5% to today ✓

Our analytic regime reads on this name, dated and marked against the screened price. Small sample per name, and separate from the daily-framework accuracy on the Track Record page.

The full research record, in depth, below
The Label · The Season, Not the Day

This name holds its distribution label.

Structure Therapeutics Inc. holds its Distribution at $27.67. The statistical read favours the sellers, held for 97 days.

As held on the ledger · 2026-10-02
PhaseDistribution · caution
Quantitative stateThe statistical read favours the sellers, held for 97 days
Price at the screen$27.67
ValuationN/A trailing · -13.10 forward price to earnings
Values screenFAIL · score 70.0
Beta-1.52
The Workings

Five Screens, Shown in Full

Does not pass. Interest-bearing securities

TestFigureLimitWhat it meansStatus
Business activity Permissible Core business clean Its core business isn't built on prohibited lines: no gambling, alcohol, tobacco, weapons, or interest-based lending. Pass
Debt load 0.41% Below 33% Interest-bearing debt is just 0.4% of its assets, well under the one-third ceiling: it does not run on borrowed money. Pass
Interest-bearing cash 40.82% Below 33% Interest-bearing cash and securities are 40.8% of assets, above the one-third limit. Fail
Receivables 56.80% Below 49% Money owed to the company is 56.8% of assets, above the 49% limit. Fail
Revenue purity Excluded Below 5% of revenue comes from non-compliant sources, over the 5% line. Fail

Five checks adapted from AAOIFI screening standards: business activity plus four balance-sheet ratios. All five must pass for ethical clearance. Every figure is arithmetic on public accounts, not judgement.

The Ethical Read

Why It Falls Short, in Plain English

Structure Therapeutics's business is fine, but its cash and interest-bearing securities are about 41% of its assets, well over the ~33% line, so it does not pass on the financial screens.

Read as at 2026-10-04. It updates when the underlying figures move, and past reads are kept below.

What the Numbers Say It Is Worth

The Fair Value Range

70.00Conservative70.00Base case70.00Growth case 27.67Price

Fair value range in USD, drawn from the 2026-10-02 screen. The gold marker is the market price at the same screen. A 100.0% margin of safety to the base estimate.

The Street's Range
70.00Street low 101.00Street average 145.00Street high 27.67Price

Third-party analyst targets: 15 covering, consensus None. The average target sits +265% from the screen price.

Reading the gap · Both our model and the analysts see meaningful upside from here.

Price History & Projections
$155$83$12TODAY3y agoPROJECTIONStreet high$145.00 +252%Street avg$101.00 +145%Conservative$70.00 +70%Our fair value$70.00 +70%

Where it has been, where the models see it going. History from market close data; projection points are our fair-value estimates and third-party analyst targets, dated to the 2026-10-02 screen.

Fair value and rating are our own model estimates; the Street's range reflects third-party analyst estimates. Analysis, not advice.

The Business, in Plain Words

Clinical biotech with no profits or data

Imagine handing cash to a lab team that has never turned a profit and cannot show basic financial ratios. Structure Therapeutics is exactly that, a clinical stage player developing oral molecules for chronic disease. The opportunity rating sits at none, the ethical screen returns insufficient data, and with zero profit margin plus negative fifteen percent return on equity the business offers nothing to anchor a position.

Forward earnings sit at a negative twenty five times multiple while the share price of forty eight dollars trades at half the analyst median target. That gap looks tempting only until the complete absence of moat data and financial ratios is factored in. Without those foundations any apparent margin of safety remains an accounting mirage.

Clinical trials can fail at any stage, cash burn is constant, and the ethical gaps alone rule out further work. Analysis, not advice.

The fundamentals · plain-English read
Forward P/E-13.1x
EPS, trailing-3.03
EPS, forward-2.11
Profit margin0.0%currently unprofitable
Return on equity-20.2%not currently earning a positive return on equity
FCF yield-6.03%
Debt to equity0.46minimal debt: a conservative balance sheet
Current ratio20.75comfortably covers its short-term bills
Beta-1.52barely tracks the market's swings
Short interest, float0.13%
52-week range25.59 - 94.90
Market cap$2.0B
Employees220

The risks · The things to watch: it's a small-cap, so the share price can swing harder than the market; as a biotechnology name, trial and regulatory outcomes can move it sharply either way.

Plain-English interpretation of our own screen data. Analysis, not advice.

Where & How to Trade

GPCR trades on Nasdaq. As a listed security it is accessible through almost any international broker offering its home market. New to this, or investing from abroad? Our guide to accessing global markets covers brokers, currencies and the practical steps.

The Dated Journal · Newest First, Never Edited

Every Entry, As Written

2026-10-02 Distribution · changed $35.00 -29.1% Entry 6

The framework has shifted from accumulation to distribution since the last review. Smart money appears to be selling into strength. Institutional holders may be rotating out. Price has moved down 29.1% since our last review. Ethical screening: FAIL. This security does not pass our values-based screening criteria. The risk-adjusted return profile shows modest positive risk-adjusted returns. Our composite framework grades it C. Technically it is momentum reading neutral. Over the past year the shares are up 89%. Our forward projection puts the odds of a 10% gain over the next month near 33%. The street (16 analysts) rates it none, with a mean price target of $106.

2026-08-31 Accumulation · changed $49.35 +1.8% Entry 5

The framework has shifted from markup to accumulation since the last review. Smart money appears to be quietly building positions. This typically precedes a markup phase. Price has moved up 1.8% since our last review. Ethical screening: FAIL. This security does not pass our values-based screening criteria. The risk-adjusted return profile shows good risk-adjusted returns. Our composite framework grades it C. Technically it is momentum reading neutral. Over the past year the shares are up 89%. Our forward projection puts the odds of a 10% gain over the next month near 33%. The street (16 analysts) rates it none, with a mean price target of $106.

2026-07-31 Markup · changed $48.48 +12.9% Entry 4

The framework has shifted from markdown to markup since the last review. Price is trending higher with momentum. The crowd has caught on and buyers are in control. Price has moved up 12.9% since our last review. Ethical screening: FAIL. This security does not pass our values-based screening criteria. The risk-adjusted return profile shows good risk-adjusted returns. Our composite framework grades it C. Technically it is momentum reading neutral. Over the past year the shares are up 89%. Our forward projection puts the odds of a 10% gain over the next month near 33%. The street (16 analysts) rates it none, with a mean price target of $106.

2026-07-18 Markdown $42.93 +0.0% Entry 3

The framework reads markdown. Price is trending lower. Sellers are in control and the prior trend has reversed. Price has moved down 0.0% since our last review. Ethical screening: FAIL. This security does not pass our values-based screening criteria. The risk-adjusted return profile shows modest positive risk-adjusted returns. Our composite framework grades it C. Technically it is momentum reading neutral. Over the past year the shares are up 89%. Our forward projection puts the odds of a 10% gain over the next month near 33%. The street (16 analysts) rates it none, with a mean price target of $106.

2026-07-03 Markdown $42.93 +0.0% Entry 2

The framework reads markdown. Price is trending lower. Sellers are in control and the prior trend has reversed. Price has moved down 0.0% since our last review. Ethical screening: FAIL. This security does not pass our values-based screening criteria. The risk-adjusted return profile shows modest positive risk-adjusted returns.

2026-07-02 Markdown $42.93 Entry 1

The framework reads markdown. Price is trending lower. Sellers are in control and the prior trend has reversed. Ethical screening: FAIL. This security does not pass our values-based screening criteria. The risk-adjusted return profile shows modest positive risk-adjusted returns.

Each entry above was written on its date, before the outcome. A journal you can prune is not a journal.

Latest News · What the Market Is Reading on GPCR

Headlines from third-party outlets, linked for reference: not our reporting, not advice.

Related Securities · Others in GPCR's Space

Screened names in the same industry · explore each on its own page.

What Holding Actually Paid · Price Plus Dividends
If $1,000 had been placed · historical, not a promise
PeriodPrice thenPrice returnDivs per share$1,000 becameTotal return
1 month $38.32 +7.6% · $1,076 +7.6%
2 months $54.51 -24.3% · $757 -24.3%
3 months $54.58 -24.4% · $756 -24.4%
6 months $67.44 -38.9% · $612 -38.9%
1 year $21.83 +88.9% · $1,889 +88.9%
2 years $52.91 -22.1% · $779 -22.1%
3 years $34.01 +21.3% · $1,213 +21.3%

Historical returns from market close data. Past performance does not guarantee future results.

The Ledger's Promise

This entry now belongs to the ledger. Whatever GPCR does next, these words stay.

Structure Therapeutics Inc. · GPCR · Distribution · $27.67
Recorded 2026-10-02 · before the outcome · scored mechanically

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