How this company measures up on the fundamentals that matter
MeiraGTx Holdings plc, a clinical-stage genetic medicines company, focusing on developing treatments for patients with serious diseases. The company develops various therapies for ocular diseases, including inherited retinal diseases and large degenerative ocular diseases; neurodegenerative diseases; and xerostomia. It is also develops AAV-AQP1 for radiation-induced grade 2/3 radiation-induced xerostomia, as well as for Sjogren's syndrome; AAV-GAD in Phase 2 trial for Parkinson's disease; AAV-RPE65 in Phase 2 trial for RPE65-associated retinal dystrophy; and AAV-CNGB3 and AAV-CNGA3, which are both in Phase ½ clinical trial for achromatopsia, as well as offers AAV-AIPL1 for Leber congenital amaurosis (LCA) 4. In addition, the company's products under preclinical development include AAV-RDH12 for retinol dehydrogenase 12 mutation-associated retinal dystrophy; AAV-BBS10 for Bardet-Biedl syndrome (BBS) due to BBS10 mutations; AAV-RetGC for LCA type 1; and AAV-UPF1 for amyotrophic lateral sclerosis, as well as programs for Alzheimer's disease, and wet and dry neovascular age related macular degeneration. Further, it provides riboswitch platform for the delivery of metabolic peptides; and cell therapies for oncology, autoimmune disease, and long term intractable pain. The company has collaborations with Johnson & Johnson Innovative Medicine for the research, development, and commercialization of gene therapies for the treatment of inherited retinal disease; and Hologen Limited for the research, development, manufacture, and commercialization of AAV-GAD investigational gene therapy for the treatment of Parkinson's disease, AAV-BDNF investigational gene therapy for genetic obesity disorders, and other genetic medicines to the central nervous system. MeiraGTx Holdings plc was founded in 2015 and is based in New York, New York.
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Statistical analysis of price behaviour, risk, and market regime — independent of fundamental data
Trading characteristics and market positioning
Balance sheet strength and cash generation — the foundation of long-term value
SEC Form 4 filings — what company insiders are buying and selling
| Date | Insider | Title | Type | Shares | Value |
|---|---|---|---|---|---|
| 2026-05-19 | FORBES ALEXANDRIA | Chief Executive Officer | 62,000 | $568,540 | |
| 2026-04-21 | GIROUX RICHARD | Chief Operating Officer | 56,000 | $572,320 | |
| 2026-04-17 | PERCEPTIVE ADVISORS, L.L.C. | Beneficial Owner of more than 10% of a Class of Security | 555,555 | $4,999,995 | |
| 2026-04-07 | NAYLOR STUART | Officer | 27,661 | $258,907 | |
| 2026-03-24 | FORBES ALEXANDRIA | Chief Executive Officer | 62,000 | $459,420 | |
| 2026-02-20 | FORBES ALEXANDRIA | Chief Executive Officer | 62,500 | — | |
| 2026-02-20 | ZELDIN ROBERT K | Officer | 7,500 | — | |
| 2026-02-20 | GIROUX RICHARD | Chief Operating Officer | 60,000 | — | |
| 2026-02-20 | NAYLOR STUART | Officer | 25,000 | — | |
| 2026-02-20 | WOLLIN ROBERT J | General Counsel | 11,250 | — |
Data sourced from public filings and market feeds. Not financial advice. Updated: 2026-05-15