The framework reads markup. Price is trending higher with momentum. The crowd has caught on and buyers are in control. Price has moved up 30.5% since our last review. Ethical screening: FAIL. This security does not pass our values-based screening criteria. The risk-adjusted return profile shows modest positive risk-adjusted returns. Our composite framework grades it B. Technically it is holding around 8% above its long-term trend line with momentum reading neutral. Over the past year the shares are up 19%. Our forward projection puts the odds of a 10% gain over the next month near 28%. The street (16 analysts) rates it strong buy, with a mean price target of $38.
Dyne Therapeutics, Inc. DYN
An entry written while the outcome is still unknown. It will be scored by what the market does next, and it will never be edited to look cleverer than it was.
In plain words · Dyne Therapeutics, Inc., a clinical-stage neuromuscular disease company, focuses on discovering and developing therapeutics for neuromuscular diseases in the United States.
read at $23.74
Dyne Therapeutics, Inc. holds its Markup at $23.74.
- PHPhase · the trend structure carries the Markup label
- INInsiders · no filings inside 60 days, left as found
- POPositioning · no disclosures inside 60 days, left as found
- OPOptions · no verdict drawn today, left as found
- SCScreen · screen not yet scored
- edge confirmed
- edge broken
- edge forming
Each arm is one independent read. Conviction is not a single call, it is how many edges converge.
The investor read · the season, not the day
| Phase | Markup |
| Quantitative state | Consolidating, no directional conviction, held for 36 days |
| Price | $23.74 |
| Valuation | N/A trailing · -8.08 forward price to earnings |
| Values screen | Not scored · score 70.0 |
| Beta | 1.06 |
The opportunity · what the numbers say it is worth
Price history & projections · where it has been, where the models see it going
The valuation journey · where the price sits against fair value and the Street
Green marks levels above today's price, red below; the shaded band is the gap between the price and our fair value.
Reading the gap · Both our model and the analysts see meaningful upside from here.
| Profit margin | 0.00% |
| Debt to equity | 19.50 |
| Analyst consensus | Strong Buy · 15 covering |
Fair value and rating are our own model estimates; target range reflects third-party analyst estimates. Analysis, not advice.
The values screen, explained · five checks, plain English
This security has not been fully scored against the values screen yet.
- Business activity Its core business isn't built on prohibited lines — no gambling, alcohol, tobacco, weapons, or interest-based lending. Pass
- Debt load Interest-bearing debt is of its assets, above the one-third ceiling the screen allows. Fail
- Interest-bearing cash Interest-bearing cash and securities are of assets, above the one-third limit. Fail
- Receivables Money owed to the company is of assets, above the 49% limit. Fail
- Revenue purity of revenue comes from non-compliant sources, over the 5% line. Fail
Every security is read against two recognised standards: our stricter asset-based screen (ratios measured against total assets) and the more widely used market-value standard (measured against market capitalisation). Where they agree we say so plainly; where they part ways — almost always on the debt check — we show both readings and mark it, because that disagreement is the finding, not a fault. We report the score; you and your scholar make the call.
The business, in plain words · what the numbers mean
Clinical Biotech Stumbles on Missing Ethical Data
Dyne is trying to build drugs that could one day treat rare muscle wasting diseases, the kind that leave families waiting years for any real option. Yet the company is still clinical stage, burning cash with no approved products and zero profit margin to show for it. That leaves the investment case resting on hope and analyst targets rather than any track record of turning science into cash.
We pass because the ethical screen returns insufficient data and the opportunity rating sits at none. Forward earnings sit at a negative 8.1 times while return on equity runs at minus 59 percent, the typical profile for a firm that has never made money. Without the basic financial ratios needed for a proper screen, there is no foundation to weigh the business against our standards.
High failure rates in neuromuscular trials add another layer of risk, and currency or sector swings could hit sentiment fast. The market may price in success at forty dollars, but without earnings or ethical clarity that number remains just a guess. Analysis, not advice.
| Forward P/E | -8.1x |
| Profit margin | 0.0% currently unprofitable |
| Return on equity | -58.9% not currently earning a positive return on equity |
| Debt to equity | 0.19 minimal debt — a conservative balance sheet |
| Current ratio | 19.92 comfortably covers its short-term bills |
| Beta | 1.06 moves a little more than the market |
| Market cap | $3.9B |
| Employees | 263 |
The risks · The things to watch: as a biotechnology name, trial and regulatory outcomes can move it sharply either way.
Plain-English interpretation of our own screen data. Analysis, not advice.
Related securities · others in DYN's space worth a look
Screened names in the same industry · explore each on its own page.
Where & how to trade · wherever in the world you are
DYN trades on Nasdaq. As a US-listed security it is accessible through almost any international broker offering US markets. New to this, or investing from outside the US? Our guide to accessing global markets covers brokers, currencies and the practical steps.
The trader read · the latest dated commentary
The dated journal · newest first, never edited
The framework reads markup. Price is trending higher with momentum. The crowd has caught on and buyers are in control. Price has moved down 0.0% since our last review. Ethical screening: FAIL. This security does not pass our values-based screening criteria. The risk-adjusted return profile shows modest positive risk-adjusted returns. Our composite framework grades it B. Technically it is holding around 8% above its long-term trend line with momentum reading neutral. Over the past year the shares are up 19%. Our forward projection puts the odds of a 10% gain over the next month near 28%. The street (16 analysts) rates it strong buy, with a mean price target of $38.
The framework reads markup. Price is trending higher with momentum. The crowd has caught on and buyers are in control. Price has moved down 0.0% since our last review. Ethical screening: FAIL. This security does not pass our values-based screening criteria. The risk-adjusted return profile shows modest positive risk-adjusted returns.
The framework reads markup. Price is trending higher with momentum. The crowd has caught on and buyers are in control. Ethical screening: FAIL. This security does not pass our values-based screening criteria. The risk-adjusted return profile shows modest positive risk-adjusted returns.
Each entry above was written on its date, before the outcome. A journal you can prune is not a journal.
The political ledger · congressional disclosures
| Date | Politician | Party | Type | Amount |
|---|---|---|---|---|
| 2025-01-15 | Mark Green | buy | 15000 | |
| 10 Jun2026 | Dwight Evans | Democrat | sell | 1K–15K |
| 1 May2026 | Ro Khanna | Democrat | buy | 1K–15K |
| 1 May2026 | Ro Khanna | Democrat | buy | 1K–15K |
What holding actually paid · price plus dividends
| Period | Price then | Price return | Divs per share | $1,000 became | Total return |
|---|---|---|---|---|---|
| 1 month | $18.46 | -4.6% | · | $955 | -4.6% |
| 2 months | $18.68 | -5.7% | · | $943 | -5.7% |
| 3 months | $18.06 | -2.4% | · | $976 | -2.4% |
| 6 months | $19.42 | -9.3% | · | $907 | -9.3% |
| 1 year | $14.78 | +19.2% | · | $1,192 | +19.2% |
| 2 years | $31.50 | -44.1% | · | $559 | -44.1% |
| 3 years | $12.96 | +36.0% | · | $1,360 | +36.0% |
| 5 years | $20.52 | -14.1% | · | $859 | -14.1% |
Historical returns from market close data. Past performance does not guarantee future results.