The framework has shifted from markup to accumulation since the last review. Smart money appears to be quietly building positions. This typically precedes a markup phase. Price has moved up 11.0% since our last review. Ethical screening: FAIL. This security does not pass our values-based screening criteria. The risk-adjusted return profile shows modest positive risk-adjusted returns. Our composite framework grades it C. Technically it is holding around 8% above its long-term trend line with momentum reading neutral. Over the past year the shares are up 19%. Our forward projection puts the odds of a 10% gain over the next month near 28%. The street (16 analysts) rates it strong buy, with a mean price target of $38.
Dyne Therapeutics, Inc.
DYN · Nasdaq · USD · Market cap $4.9B · 263 employees
Dyne Therapeutics, Inc., a clinical-stage neuromuscular disease company, focuses on discovering and developing therapeutics for neuromuscular diseases in the United States.
FAIL · Does not pass the screenAt the last full screen
2026-08-26
Screened 2026-08-26 · the tape above runs as of 10:31 UTC · two dates, stated on purpose · verdict and workings shown in full · never trimmed
This name holds its markdown label.
Dyne Therapeutics, Inc. holds its Markdown at $26.36. Consolidating, no directional conviction, held for 16 days.
| Phase | Markdown · caution |
| Quantitative state | Consolidating, no directional conviction, held for 16 days |
| Price at the screen | $26.36 |
| Valuation | N/A trailing · -7.89 forward price to earnings |
| Values screen | FAIL · score 70.0 |
| Beta | 1.08 |
Five Screens, Shown in Full
Does not pass. Accounts receivable
| Test | Figure | Limit | What it means | Status |
|---|---|---|---|---|
| Business activity | Permissible | Core business clean | Its core business isn't built on prohibited lines: no gambling, alcohol, tobacco, weapons, or interest-based lending. | Pass |
| Debt load | 14.25% | Below 33% | Interest-bearing debt is just 14.3% of its assets, well under the one-third ceiling: it does not run on borrowed money. | Pass |
| Interest-bearing cash | 18.30% | Below 33% | Cash held in interest-bearing accounts and securities is 18.3% of assets, under the one-third limit. | Pass |
| Receivables | 75.27% | Below 49% | Money owed to the company is 75.3% of assets, above the 49% limit. | Fail |
| Revenue purity | Excluded | Below 5% | of revenue comes from non-compliant sources, over the 5% line. | Fail |
Five checks adapted from AAOIFI screening standards: business activity plus four balance-sheet ratios. All five must pass for ethical clearance. Every figure is arithmetic on public accounts, not judgement.
What the Numbers Say It Is WorthThe Fair Value Range
Fair value range in USD, drawn from the 2026-08-26 screen. The gold marker is the market price at the same screen. A 51.7% margin of safety to the base estimate.
Third-party analyst targets: 15 covering, consensus Strong Buy. The average target sits +52% from the screen price.
Reading the gap · Both our model and the analysts see meaningful upside from here.
Price History & ProjectionsWhere it has been, where the models see it going. History from market close data; projection points are our fair-value estimates and third-party analyst targets, dated to the 2026-08-26 screen.
Fair value and rating are our own model estimates; the Street's range reflects third-party analyst estimates. Analysis, not advice.
The Business, in Plain WordsClinical Biotech Stumbles on Missing Ethical Data
Dyne is trying to build drugs that could one day treat rare muscle wasting diseases, the kind that leave families waiting years for any real option. Yet the company is still clinical stage, burning cash with no approved products and zero profit margin to show for it. That leaves the investment case resting on hope and analyst targets rather than any track record of turning science into cash.
We pass because the ethical screen returns insufficient data and the opportunity rating sits at none. Forward earnings sit at a negative 8.1 times while return on equity runs at minus 59 percent, the typical profile for a firm that has never made money. Without the basic financial ratios needed for a proper screen, there is no foundation to weigh the business against our standards.
High failure rates in neuromuscular trials add another layer of risk, and currency or sector swings could hit sentiment fast. The market may price in success at forty dollars, but without earnings or ethical clarity that number remains just a guess. Analysis, not advice.
| Forward P/E | -7.9x |
| EPS, trailing | -3.26 |
| EPS, forward | -3.34 |
| Profit margin | 0.0%currently unprofitable |
| Return on equity | -81.6%not currently earning a positive return on equity |
| FCF yield | -6.44% |
| Debt to equity | 0.33minimal debt: a conservative balance sheet |
| Current ratio | 12.02comfortably covers its short-term bills |
| Beta | 1.08moves a little more than the market |
| Short interest, float | 0.15% |
| 52-week range | 11.92 - 27.31 |
| Market cap | $4.9B |
| Employees | 263 |
The risks · The things to watch: as a biotechnology name, trial and regulatory outcomes can move it sharply either way.
Plain-English interpretation of our own screen data. Analysis, not advice.
Where & How to TradeDYN trades on Nasdaq. As a listed security it is accessible through almost any international broker offering its home market. New to this, or investing from abroad? Our guide to accessing global markets covers brokers, currencies and the practical steps.
Every Entry, As Written
The framework reads markup. Price is trending higher with momentum. The crowd has caught on and buyers are in control. Price has moved up 30.5% since our last review. Ethical screening: FAIL. This security does not pass our values-based screening criteria. The risk-adjusted return profile shows modest positive risk-adjusted returns. Our composite framework grades it B. Technically it is holding around 8% above its long-term trend line with momentum reading neutral. Over the past year the shares are up 19%. Our forward projection puts the odds of a 10% gain over the next month near 28%. The street (16 analysts) rates it strong buy, with a mean price target of $38.
The framework reads markup. Price is trending higher with momentum. The crowd has caught on and buyers are in control. Price has moved down 0.0% since our last review. Ethical screening: FAIL. This security does not pass our values-based screening criteria. The risk-adjusted return profile shows modest positive risk-adjusted returns. Our composite framework grades it B. Technically it is holding around 8% above its long-term trend line with momentum reading neutral. Over the past year the shares are up 19%. Our forward projection puts the odds of a 10% gain over the next month near 28%. The street (16 analysts) rates it strong buy, with a mean price target of $38.
The framework reads markup. Price is trending higher with momentum. The crowd has caught on and buyers are in control. Price has moved down 0.0% since our last review. Ethical screening: FAIL. This security does not pass our values-based screening criteria. The risk-adjusted return profile shows modest positive risk-adjusted returns.
The framework reads markup. Price is trending higher with momentum. The crowd has caught on and buyers are in control. Ethical screening: FAIL. This security does not pass our values-based screening criteria. The risk-adjusted return profile shows modest positive risk-adjusted returns.
Each entry above was written on its date, before the outcome. A journal you can prune is not a journal.
Screened names in the same industry · explore each on its own page.
| Date | Politician | Party | Type | Amount |
|---|---|---|---|---|
| 7 Jul2026 | Ro Khanna | Democrat | sell | 1K–15K |
| 7 Jul2026 | Ro Khanna | Democrat | sell | 1K–15K |
| 7 Jul2026 | Ro Khanna | Democrat | sell | 1K–15K |
| 3 May2024 | Tommy Tuberville | Republican | sell | 1K–15K |
| 27 Mar2026 | Alan Armstrong | Republican | buy | 1K–15K |
| Period | Price then | Price return | Divs per share | $1,000 became | Total return |
|---|---|---|---|---|---|
| 1 month | $18.46 | -4.6% | · | $955 | -4.6% |
| 2 months | $18.68 | -5.7% | · | $943 | -5.7% |
| 3 months | $18.06 | -2.4% | · | $976 | -2.4% |
| 6 months | $19.42 | -9.3% | · | $907 | -9.3% |
| 1 year | $14.78 | +19.2% | · | $1,192 | +19.2% |
| 2 years | $31.50 | -44.1% | · | $559 | -44.1% |
| 3 years | $12.96 | +36.0% | · | $1,360 | +36.0% |
| 5 years | $20.52 | -14.1% | · | $859 | -14.1% |
Historical returns from market close data. Past performance does not guarantee future results.
This entry now belongs to the ledger. Whatever DYN does next, these words stay.
Thirteen thousand names carry this page. One desk keeps them honest.
Membership opens the full screen archive, the composites built from it, and the daily coverage that prices what the screen approves.
Join the deskScreening is research, not a fatwa and not financial advice. Figures are drawn from public accounts at the screen date shown. Always manage your risk.