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The Screen · Healthcare · Biotechnology

Alumis Inc. logoAlumis Inc.

ALMS · Nasdaq · USD · Market cap $975M · 225 employees

Alumis Inc., a clinical stage biopharmaceutical company, focuses on the development and commercialization of medicines for autoimmune disorders.

FAIL · Does not pass the screen
7.90 USD

Screen close, 2026-09-21 · not a live quote
Last reviewed 14 days ago

Screened 2026-09-21 · the tape above runs as of 03:09 UTC · two dates, stated on purpose · verdict and workings shown in full · never trimmed

PRICE · FAIR-VALUE RANGE1M3M6MYTD1Y3Y5Y
25.0039.0047.24

What this means: price 7.90 against the desk's fair-value range, base estimate 39.00, over the last year.

Current read
Markdown ?
Screened · screened 2026-09-21
  • Trend Markdown
  • Insiders no filings inside 60 days, left as found
  • Positioning no disclosures inside 60 days, left as found
  • Options no verdict drawn today, left as found
  • Ethical does not pass the values gate
Price7.90 USD
Fair value39.00
Ethical score70.0/100
Our investment reviews on this name
2026-09-21Read Distribution8.40-6.0% to today ✓
2026-07-02Read Markdown24.15-67.3% to today ✓

Our analytic regime reads on this name, dated and marked against the screened price. Small sample per name, and separate from the daily-framework accuracy on the Track Record page.

The full research record, in depth, below
The Label · The Season, Not the Day

This name holds its markdown label.

Alumis Inc. holds its Markdown at $7.90. Consolidating, no directional conviction, held for 2 days.

As held on the ledger · 2026-09-21
PhaseMarkdown · caution
Quantitative stateConsolidating, no directional conviction, held for 2 days
Price at the screen$7.90
ValuationN/A trailing · -2.92 forward price to earnings
Values screenFAIL · score 70.0
Beta-0.79
The Workings

Five Screens, Shown in Full

Does not pass. Interest-bearing securities

TestFigureLimitWhat it meansStatus
Business activity Permissible Core business clean Its core business isn't built on prohibited lines: no gambling, alcohol, tobacco, weapons, or interest-based lending. Pass
Debt load 8.96% Below 33% Interest-bearing debt is just 9.0% of its assets, well under the one-third ceiling: it does not run on borrowed money. Pass
Interest-bearing cash 53.12% Below 33% Interest-bearing cash and securities are 53.1% of assets, above the one-third limit. Fail
Receivables 22.27% Below 49% Money owed to the company is 22.3% of assets, under the 49% limit. Pass
Revenue purity 58.96% Below 5% 59.0% of revenue comes from non-compliant sources, over the 5% line. Fail

Five checks adapted from AAOIFI screening standards: business activity plus four balance-sheet ratios. All five must pass for ethical clearance. Every figure is arithmetic on public accounts, not judgement.

The Ethical Read

Why It Falls Short, in Plain English

Alumis's business is fine, but its cash and interest-bearing securities are about 53% of its assets, well over the ~33% line, so it does not pass on the financial screens.

Read as at 2026-10-04. It updates when the underlying figures move, and past reads are kept below.

What the Numbers Say It Is Worth

The Fair Value Range

25.00Conservative39.00Base case47.24Growth case 7.90Price

Fair value range in USD, drawn from the 2026-09-21 screen. The gold marker is the market price at the same screen. A 393.7% margin of safety to the base estimate.

The Street's Range
15.00Street low 32.00Street average 46.00Street high 7.90Price

Third-party analyst targets: 8 covering, consensus Strong Buy. The average target sits +305% from the screen price.

Reading the gap · Both our model and the analysts see meaningful upside from here.

Price History & Projections
$49.4$24.7$-0.1TODAY1y agoPROJECTIONStreet high$46.00 +126%Our fair value$39.00 +91%Street avg$32.00 +57%Conservative$25.00 +23%

Where it has been, where the models see it going. History from market close data; projection points are our fair-value estimates and third-party analyst targets, dated to the 2026-09-21 screen.

Fair value and rating are our own model estimates; the Street's range reflects third-party analyst estimates. Analysis, not advice.

The Business, in Plain Words

Biotech Pipeline Hopes Fail Our Basic Test

Picture a lab team staking everything on one TYK2 pill for psoriasis and lupus. That is Alumis today, a clinical-stage name with no approved products and revenue already shrinking fast. We pass despite a fair value gap and a clean ethical screen because the underlying business shows zero profits, deeply negative returns on equity and a forward multiple that simply reflects expected losses.

Analysts see upside to around forty dollars and rate the shares a strong buy, yet those calls rest on future trial data that may or may not arrive. Current metrics paint a firm still burning cash with no moat visible and growth running sharply negative. The valuation gap looks attractive on paper but offers little protection when the next readout disappoints.

Risks sit mainly in binary trial outcomes, dilution and the usual biotech cash burn, all of which explain why the opportunity rating stays at none. Analysis, not advice.

The fundamentals · plain-English read
Forward P/E-2.9x
EPS, trailing-4.11
EPS, forward-2.87
Revenue growth-37.7%revenue is shrinking
Profit margin0.0%currently unprofitable
Return on equity-93.6%not currently earning a positive return on equity
FCF yield-19.19%
Debt to equity0.08minimal debt: a conservative balance sheet
Current ratio6.74comfortably covers its short-term bills
Beta-0.79barely tracks the market's swings
Short interest, float0.07%
52-week range3.76 - 31.35
Market cap$975M
Employees225

The risks · The things to watch: it's a small-cap, so the share price can swing harder than the market; as a biotechnology name, trial and regulatory outcomes can move it sharply either way.

Plain-English interpretation of our own screen data. Analysis, not advice.

Where & How to Trade

ALMS trades on Nasdaq. As a listed security it is accessible through almost any international broker offering its home market. New to this, or investing from abroad? Our guide to accessing global markets covers brokers, currencies and the practical steps.

The Dated Journal · Newest First, Never Edited

Every Entry, As Written

2026-10-02 Distribution $7.90 -6.0% Entry 8

The framework reads distribution. Smart money appears to be selling into strength. Institutional holders may be rotating out. Price has moved down 6.0% since our last review. Ethical screening: FAIL. This security does not pass our values-based screening criteria. The risk-adjusted return profile shows modest positive risk-adjusted returns. Our composite framework grades it C. Technically it is holding around 39% above its long-term trend line with momentum reading bearish. Over the past year the shares are up 507%. Our forward projection puts the odds of a 10% gain over the next month near 37%. The street (10 analysts) rates it strong buy, with a mean price target of $40.

2026-09-21 Distribution · changed $8.40 -69.6% Entry 7

The framework has shifted from markdown to distribution since the last review. Smart money appears to be selling into strength. Institutional holders may be rotating out. Price has moved down 69.6% since our last review. Ethical screening: FAIL. This security does not pass our values-based screening criteria. The risk-adjusted return profile shows modest positive risk-adjusted returns. Our composite framework grades it C. Technically it is holding around 39% above its long-term trend line with momentum reading bearish. Over the past year the shares are up 507%. Our forward projection puts the odds of a 10% gain over the next month near 37%. The street (10 analysts) rates it strong buy, with a mean price target of $40.

2026-08-21 Markdown $27.60 -3.7% Entry 6

The framework reads markdown. Price is trending lower. Sellers are in control and the prior trend has reversed. Price has moved down 3.7% since our last review. Ethical screening: FAIL. This security does not pass our values-based screening criteria. The risk-adjusted return profile shows good risk-adjusted returns. Our composite framework grades it C. Technically it is holding around 39% above its long-term trend line with momentum reading bearish. Over the past year the shares are up 507%. Our forward projection puts the odds of a 10% gain over the next month near 37%. The street (10 analysts) rates it strong buy, with a mean price target of $40.

2026-07-21 Markdown $28.66 +18.7% Entry 5

The framework reads markdown. Price is trending lower. Sellers are in control and the prior trend has reversed. Price has moved up 18.7% since our last review. Ethical screening: PASS with passing ethical screen. The risk-adjusted return profile shows good risk-adjusted returns. Our composite framework grades it C. Technically it is holding around 39% above its long-term trend line with momentum reading bearish. Over the past year the shares are up 507%. Our forward projection puts the odds of a 10% gain over the next month near 37%. The street (10 analysts) rates it strong buy, with a mean price target of $40.

2026-07-18 Markdown $24.15 +0.0% Entry 4

The framework reads markdown. Price is trending lower. Sellers are in control and the prior trend has reversed. Price has moved down 0.0% since our last review. Ethical screening: PASS with passing ethical screen. The risk-adjusted return profile shows good risk-adjusted returns. Our composite framework grades it C. Technically it is holding around 39% above its long-term trend line with momentum reading bearish. Over the past year the shares are up 507%. Our forward projection puts the odds of a 10% gain over the next month near 37%. The street (10 analysts) rates it strong buy, with a mean price target of $40.

2026-07-17 Markdown $24.15 +0.0% Entry 3

The framework reads markdown. Price is trending lower. Sellers are in control and the prior trend has reversed. Price has moved down 0.0% since our last review. Ethical screening: PASS with passing ethical screen (70). The risk-adjusted return profile shows good risk-adjusted returns. Our composite framework grades it C. Technically it is holding around 39% above its long-term trend line with momentum reading bearish. Over the past year the shares are up 507%. Our forward projection puts the odds of a 10% gain over the next month near 37%. The street (10 analysts) rates it strong buy, with a mean price target of $40.

2026-07-03 Markdown $24.15 +0.0% Entry 2

The framework reads markdown. Price is trending lower. Sellers are in control and the prior trend has reversed. Price has moved down 0.0% since our last review. Ethical screening: PASS with passing ethical screen (70). The risk-adjusted return profile shows good risk-adjusted returns.

2026-07-02 Markdown $24.15 Entry 1

The framework reads markdown. Price is trending lower. Sellers are in control and the prior trend has reversed. Ethical screening: PASS with passing ethical screen (70). The risk-adjusted return profile shows good risk-adjusted returns.

Each entry above was written on its date, before the outcome. A journal you can prune is not a journal.

Latest News · What the Market Is Reading on ALMS

Headlines from third-party outlets, linked for reference: not our reporting, not advice.

Related Securities · Others in ALMS's Space

Screened names in the same industry · explore each on its own page.

What Holding Actually Paid · Price Plus Dividends
If $1,000 had been placed · historical, not a promise
PeriodPrice thenPrice returnDivs per share$1,000 becameTotal return
1 month $23.66 -13.8% · $862 -13.8%
2 months $23.05 -11.5% · $885 -11.5%
3 months $25.03 -18.5% · $815 -18.5%
6 months $11.61 +75.6% · $1,756 +75.6%
1 year $3.36 +506.9% · $6,069 +506.9%

Historical returns from market close data. Past performance does not guarantee future results.

The Ledger's Promise

This entry now belongs to the ledger. Whatever ALMS does next, these words stay.

Alumis Inc. · ALMS · Markdown · $7.90
Recorded 2026-09-21 · before the outcome · scored mechanically

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