The analysis reads markdown. Price is trending lower. Sellers are in control and the prior trend has reversed. Price has moved down 0.0% since our last review. Ethical screening: FAIL. This security does not pass our values-based screening criteria. The risk-adjusted return profile shows good risk-adjusted returns. Our composite framework grades it C. Technically it is holding around 17% above its long-term trend line with momentum reading neutral. Over the past year the shares are up 114%. Our forward projection puts the odds of a 10% gain over the next month near 37%. The street (12 analysts) rates it buy, with a mean price target of $44. Insiders have been net sellers over the past quarter.
Edgewise Therapeutics, Inc.
EWTX · Nasdaq · USD · Market cap $4.3B · 154 employees
Edgewise Therapeutics, Inc., a biopharmaceutical company, discovers, develops, and commercializes therapies for the treatment of muscle disorders.
FAIL · Does not pass the screenPrice as of 23 Oct 2026Daily close, not a live quoteLast reviewed 6 days ago
Screened 2026-10-23 · the tape above runs as of 06:01 UTC · two dates, stated on purpose · verdict and workings shown in full · never trimmed
Key facts today
- Price39.31 USD at the 23 Oct 2026 close
- Ethical screenDoes not pass
- OptionsOpen interest leans to puts (put/call 1.25)
- Last reviewed23 Oct 2026 (6 days ago)
A summary of the dated readings below, not a live quote and not advice.
What this means: price 39.31 against the desk's fair-value range, base estimate 53.00, over the last year.
- Trend Markdown
- Insiders no filings inside 60 days, left as found
- Positioning no disclosures inside 60 days, left as found
- Options put/call open interest 1.25, read 2026-10-28
- Ethical does not pass the values gate
Our analytic regime reads on this name, dated and marked against the screened price. Small sample per name, and separate from the daily-framework accuracy on the Track Record page.
This name holds its markdown label.
Edgewise Therapeutics, Inc. holds its Markdown at $39.31. The statistical read favours the sellers, held for 34 days.
| Phase | Markdown · caution |
| Quantitative state | The statistical read favours the sellers, held for 34 days |
| Price at the screen | $39.31 |
| Valuation | N/A trailing · -22.41 forward price to earnings |
| Values screen | FAIL · score 70.0 |
| Beta | 0.36 |
Five Screens, Shown in Full
Does not pass. Interest-bearing securities
| Test | Figure | Limit | What it means | Status |
|---|---|---|---|---|
| Business activity | Permissible | Core business clean | Its core business isn't built on prohibited lines: no gambling, alcohol, tobacco, weapons, or interest-based lending. | Pass |
| Debt load | 0.72% | Below 33% | Interest-bearing debt is just 0.7% of its assets, well under the one-third ceiling: it does not run on borrowed money. | Pass |
| Interest-bearing cash | 84.86% | Below 33% | Interest-bearing cash and securities are 84.9% of assets, above the one-third limit. | Fail |
| Receivables | 11.07% | Below 49% | Money owed to the company is 11.1% of assets, under the 49% limit. | Pass |
Five checks adapted from AAOIFI screening standards: business activity plus four balance-sheet ratios. All five must pass for ethical clearance. Every figure is arithmetic on public accounts, not judgement.
The Ethical ReadWhy It Falls Short, in Plain English
Edgewise Therapeutics,'s business is fine, but its cash and interest-bearing securities are about 85% of its assets, well over the ~33% line, so it does not pass on the financial screens.
Read as at 2026-10-28. It updates when the underlying figures move, and past reads are kept below.
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The Fair Value Range
Fair value range in USD, drawn from the 2026-10-23 screen. The gold marker is the market price at the same screen. A 34.8% margin of safety to the base estimate.
Third-party analyst targets: 13 covering, consensus Strong Buy. The average target sits +35% from the screen price.
Reading the gap · Both our model and the analysts see meaningful upside from here.
Price History & ProjectionsWhere it has been, where the models see it going. History from market close data; projection points are our fair-value estimates and third-party analyst targets, dated to the 2026-10-23 screen.
Fair value and rating are our own model estimates; the Street's range reflects third-party analyst estimates. Analysis, not advice.
The Business, in Plain WordsBiotech Muscle Drug Developer Lacks Ethical Data
A patient with a rare muscle disorder waits years for any new pill that might slow the damage. Edgewise is one of several small biotechs chasing that hope with an oral candidate now in mid-stage trials, yet we pass. The ethical screen returns insufficient data because standard financial ratios are missing, and that single gap is enough to keep the name off any list we would consider.
The reported numbers tell a familiar pre-revenue story. Forward earnings sit at minus 26 times, profit margins are zero, and return on equity is minus 38 percent. Thirteen analysts still cluster around a 52 dollar median target, but those forecasts rest entirely on future trial success rather than any current cash generation or competitive edge.
Clinical failure rates in this field remain high, dilution risk is constant, and the absence of basic ratio data blocks any proper ethical review. We therefore stay away until clearer financial and governance information appears. Analysis, not advice.
| Forward P/E | -22.4x |
| EPS, trailing | -1.86 |
| EPS, forward | -1.77 |
| Profit margin | 0.0%currently unprofitable |
| Return on equity | -38.0%not currently earning a positive return on equity |
| FCF yield | -2.14% |
| Debt to equity | 0.80moderate, manageable leverage |
| Current ratio | 16.24comfortably covers its short-term bills |
| Beta | 0.36barely tracks the market's swings |
| Short interest, float | 0.15% |
| 52-week range | 14.68 - 48.51 |
| Market cap | $4.3B |
| Employees | 154 |
The risks · The things to watch: as a biotechnology name, trial and regulatory outcomes can move it sharply either way.
Plain-English interpretation of our own screen data. Analysis, not advice.
Where & How to TradeEWTX trades on Nasdaq. As a listed security it is accessible through almost any international broker offering its home market. New to this, or investing from abroad? Our guide to accessing global markets covers brokers, currencies and the practical steps.
Every Entry, As Written
The analysis reads markdown. Price is trending lower. Sellers are in control and the prior trend has reversed. Price has moved up 1.3% since our last review. Ethical screening: FAIL. This security does not pass our values-based screening criteria. The risk-adjusted return profile shows good risk-adjusted returns. Our composite framework grades it D. Technically it is holding around 12% above its long-term trend line with momentum reading bearish. Over the past year the shares are up 114%. Our forward projection puts the odds of a 10% gain over the next month near 37%. The street (12 analysts) rates it buy, with a mean price target of $44. Insiders have been net sellers over the past quarter.
The analysis reads markdown. Price is trending lower. Sellers are in control and the prior trend has reversed. Price has moved down 12.1% since our last review. Ethical screening: FAIL. This security does not pass our values-based screening criteria. The risk-adjusted return profile shows good risk-adjusted returns. Our composite framework grades it B. Technically it is holding around 36% above its long-term trend line with momentum reading bearish. Over the past year the shares are up 114%. Our forward projection puts the odds of a 10% gain over the next month near 37%. The street (12 analysts) rates it buy, with a mean price target of $44. Insiders have been net sellers over the past quarter.
The framework has shifted from markup to markdown since the last review. Price is trending lower. Sellers are in control and the prior trend has reversed. Price has moved up 0.6% since our last review. Ethical screening: FAIL. This security does not pass our values-based screening criteria. The risk-adjusted return profile shows good risk-adjusted returns. Our composite framework grades it B. Technically it is holding around 36% above its long-term trend line with momentum reading bearish. Over the past year the shares are up 114%. Our forward projection puts the odds of a 10% gain over the next month near 37%. The street (12 analysts) rates it buy, with a mean price target of $44. Insiders have been net sellers over the past quarter.
Our analysis reads markup. Price is trending higher with momentum. The crowd has caught on and buyers are in control. Price has moved up 11.6% since our last review. Ethical screening: FAIL. This security does not pass our values-based screening criteria. The risk-adjusted return profile shows good risk-adjusted returns. Our composite framework grades it B. Technically it is holding around 36% above its long-term trend line with momentum reading bearish. Over the past year the shares are up 114%. Our forward projection puts the odds of a 10% gain over the next month near 37%. The street (12 analysts) rates it buy, with a mean price target of $44. Insiders have been net sellers over the past quarter.
Our analysis reads markup. Price is trending higher with momentum. The crowd has caught on and buyers are in control. Price has moved up 14.2% since our last review. Ethical screening: FAIL. This security does not pass our values-based screening criteria. The risk-adjusted return profile shows good risk-adjusted returns. Our composite framework grades it B. Technically it is holding around 36% above its long-term trend line with momentum reading bearish. Over the past year the shares are up 114%. Our forward projection puts the odds of a 10% gain over the next month near 37%. The street (12 analysts) rates it buy, with a mean price target of $44.
Our analysis reads markup. Price is trending higher with momentum. The crowd has caught on and buyers are in control. Price has moved down 0.0% since our last review. Ethical screening: FAIL. This security does not pass our values-based screening criteria. The risk-adjusted return profile shows good risk-adjusted returns. Our composite framework grades it B. Technically it is holding around 36% above its long-term trend line with momentum reading bearish. Over the past year the shares are up 114%. Our forward projection puts the odds of a 10% gain over the next month near 37%. The street (12 analysts) rates it buy, with a mean price target of $44.
Our analysis reads markup. Price is trending higher with momentum. The crowd has caught on and buyers are in control. Price has moved down 0.0% since our last review. Ethical screening: FAIL. This security does not pass our values-based screening criteria. The risk-adjusted return profile shows good risk-adjusted returns.
Our analysis reads markup. Price is trending higher with momentum. The crowd has caught on and buyers are in control. Ethical screening: FAIL. This security does not pass our values-based screening criteria. The risk-adjusted return profile shows good risk-adjusted returns.
Each entry above was written on its date, before the outcome. A journal you can prune is not a journal.
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Headlines from third-party outlets, linked for reference: not our reporting, not advice.
Screened names in the same industry · explore each on its own page.
| Date | Insider | Title | Type | Shares | Value |
|---|---|---|---|---|---|
| 2026-08-12 | Donovan Joanne M. | CMO | S - Sale+OE | 9,441 | $412,703 |
| 2026-08-12 | Russell Alan J | Chief Scientific Officer | S - Sale+OE | 5,901 | $258,042 |
| 2026-08-12 | Moore John R | GC | S - Sale+OE | 5,016 | $219,823 |
Public filings, recorded as found. The full tape lives at Insider Intelligence.
| Period | Price then | Price return | Divs per share | $1,000 became | Total return |
|---|---|---|---|---|---|
| 1 month | $34.56 | -4.3% | · | $957 | -4.3% |
| 2 months | $32.82 | +0.8% | · | $1,008 | +0.8% |
| 3 months | $29.94 | +10.5% | · | $1,105 | +10.5% |
| 6 months | $23.43 | +41.1% | · | $1,411 | +41.1% |
| 1 year | $15.45 | +114.1% | · | $2,141 | +114.1% |
| 2 years | $17.13 | +93.1% | · | $1,931 | +93.1% |
| 3 years | $9.63 | +243.4% | · | $3,434 | +243.4% |
| 5 years | $25.91 | +27.6% | · | $1,276 | +27.6% |
Historical returns from market close data. Past performance does not guarantee future results.
This entry now belongs to the ledger. Whatever EWTX does next, these words stay.
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