The framework has shifted from distribution to markup since the last review. Price is trending higher with momentum. The crowd has caught on and buyers are in control. Price has moved up 86.5% since our last review. Ethical screening: FAIL. This security does not pass our values-based screening criteria. The risk-adjusted return profile shows modest positive risk-adjusted returns. Our composite framework grades it C. Technically it is momentum reading neutral. Over the past year the shares are up 21%. Our forward projection puts the odds of a 10% gain over the next month near 23%. The street (12 analysts) rates it none, with a mean price target of $28.
Xencor, Inc.
XNCR · Nasdaq · USD · Market cap $2.1B · 260 employees
Xencor, Inc., a clinical-stage biopharmaceutical company, focuses on the discovery and development of engineered antibodies for the treatment of cancer and autoimmune diseases.
FAIL · Does not pass the screenAt the last full screen
2026-09-01
Screened 2026-09-01 · the tape above runs as of 22:12 UTC · 11 Sep · two dates, stated on purpose · verdict and workings shown in full · never trimmed
This name holds its markup label.
Xencor, Inc. holds its Markup at $27.91. Consolidating, no directional conviction, held for 5 days.
| Phase | Markup |
| Quantitative state | Consolidating, no directional conviction, held for 5 days |
| Price at the screen | $27.91 |
| Valuation | N/A trailing · -7.97 forward price to earnings |
| Values screen | FAIL · score 70.0 |
| Beta | 0.84 |
Five Screens, Shown in Full
Does not pass. Revenue purity
| Test | Figure | Limit | What it means | Status |
|---|---|---|---|---|
| Business activity | Permissible | Core business clean | Its core business isn't built on prohibited lines: no gambling, alcohol, tobacco, weapons, or interest-based lending. | Pass |
| Debt load | 21.44% | Below 33% | Interest-bearing debt is just 21.4% of its assets, well under the one-third ceiling: it does not run on borrowed money. | Pass |
| Interest-bearing cash | 20.06% | Below 33% | Cash held in interest-bearing accounts and securities is 20.1% of assets, under the one-third limit. | Pass |
| Receivables | 9.52% | Below 49% | Money owed to the company is 9.5% of assets, under the 49% limit. | Pass |
| Revenue purity | 21.92% | Below 5% | 21.9% of revenue comes from non-compliant sources, over the 5% line. | Fail |
Five checks adapted from AAOIFI screening standards: business activity plus four balance-sheet ratios. All five must pass for ethical clearance. Every figure is arithmetic on public accounts, not judgement.
What the Numbers Say It Is WorthThe Fair Value Range
Fair value range in USD, drawn from the 2026-09-01 screen. The gold marker is the market price at the same screen. A 2.1% margin of safety to the base estimate.
Third-party analyst targets: 12 covering, consensus None. The average target sits +2% from the screen price.
Reading the gap · Our model and the Street both land near today's price: fairly valued, with no strong edge either way.
Price History & ProjectionsWhere it has been, where the models see it going. History from market close data; projection points are our fair-value estimates and third-party analyst targets, dated to the 2026-09-01 screen.
Fair value and rating are our own model estimates; the Street's range reflects third-party analyst estimates. Analysis, not advice.
The Business, in Plain WordsClinical Biotech With Shrinking Sales And Heavy Losses
Picture a lab racing to turn antibody ideas into approved drugs while sales keep sliding off a cliff. Xencor is exactly that story, a clinical stage player chasing cancer and autoimmune treatments with revenue already down 86 percent and margins at minus 177 percent. The numbers show a company burning cash fast and posting a negative 30 percent return on equity, so we pass despite the clean ethical screen and analyst enthusiasm.
The forward multiple sits at minus 4.9 times, which simply reflects deepening losses rather than any bargain. A 55 percent gap to the $27 median target looks tempting on paper, yet the underlying business shows no clear path to sustained profits or a durable moat. Strong buy ratings from twelve analysts do not change the weak operating reality.
Risk sits in the usual clinical stage traps of trial failures and dilution, made worse by the sharp revenue drop. Analysis, not advice.
| Forward P/E | -8.0x |
| EPS, trailing | -2.16 |
| EPS, forward | -3.50 |
| Revenue growth | +17.5%steady growth |
| Profit margin | -155.6%currently unprofitable |
| Return on equity | -29.1%not currently earning a positive return on equity |
| FCF yield | -4.56% |
| Debt to equity | 0.34minimal debt: a conservative balance sheet |
| Current ratio | 6.39comfortably covers its short-term bills |
| Beta | 0.84steadier than the market |
| Short interest, float | 0.27% |
| 52-week range | 7.91 - 30.61 |
| Market cap | $2.1B |
| Employees | 260 |
The risks · The things to watch: as a biotechnology name, trial and regulatory outcomes can move it sharply either way.
Plain-English interpretation of our own screen data. Analysis, not advice.
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Every Entry, As Written
The framework reads distribution. Smart money appears to be selling into strength. Institutional holders may be rotating out. Price has moved down 0.0% since our last review. Ethical screening: PASS with passing ethical screen. The risk-adjusted return profile shows negative risk-adjusted returns. Our composite framework grades it C. Technically it is momentum reading neutral. Over the past year the shares are up 21%. Our forward projection puts the odds of a 10% gain over the next month near 23%. The street (12 analysts) rates it none, with a mean price target of $28.
The framework reads distribution. Smart money appears to be selling into strength. Institutional holders may be rotating out. Price has moved down 0.0% since our last review. Ethical screening: PASS with passing ethical screen (70). The risk-adjusted return profile shows negative risk-adjusted returns.
The framework reads distribution. Smart money appears to be selling into strength. Institutional holders may be rotating out. Ethical screening: PASS with passing ethical screen (70). The risk-adjusted return profile shows negative risk-adjusted returns.
Each entry above was written on its date, before the outcome. A journal you can prune is not a journal.
Screened names in the same industry · explore each on its own page.
| Period | Price then | Price return | Divs per share | $1,000 became | Total return |
|---|---|---|---|---|---|
| 1 month | $12.79 | -7.5% | · | $925 | -7.5% |
| 2 months | $12.42 | -4.8% | · | $953 | -4.8% |
| 3 months | $11.61 | +1.9% | · | $1,019 | +1.9% |
| 6 months | $17.06 | -30.7% | · | $693 | -30.7% |
| 1 year | $9.74 | +21.5% | · | $1,215 | +21.5% |
| 2 years | $21.89 | -46.0% | · | $540 | -46.0% |
| 3 years | $26.87 | -56.0% | · | $440 | -56.0% |
| 5 years | $37.29 | -68.3% | · | $317 | -68.3% |
Historical returns from market close data. Past performance does not guarantee future results.
This entry now belongs to the ledger. Whatever XNCR does next, these words stay.
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Join the deskScreening is research, not a fatwa and not financial advice. Figures are drawn from public accounts at the screen date shown. Always manage your risk.