NAS100 29,544 +0.21% S&P 7,719 −0.38% GOLD $4,458 +0.65% BTC $79,147 −1.50% VIX 15.30 +5.30% live tape · as of 22:26 UTC · 7 Sep
Vol. II · No. 251Tuesday, 8 September 2026
TTitan Protect
The Screen · Healthcare · Biotechnology

Apellis Pharmaceuticals, Inc. logoApellis Pharmaceuticals, Inc.

APLS · Nasdaq · USD · Market cap $5.3B · 733 employees

Apellis Pharmaceuticals, Inc., a commercial-stage biopharmaceutical company, focuses on the discovery, development, and commercialization of novel therapeutic compounds to treat diseases with high unmet needs.

PASS · Titan Ethical · score 93.6
41.03 USD

At the last full screen
2026-07-19

Screened 2026-07-19 · the tape above runs as of 22:26 UTC · 7 Sep · two dates, stated on purpose · verdict and workings shown in full · never trimmed

The Label · The Season, Not the Day

This name holds its accumulation label.

Apellis Pharmaceuticals, Inc. holds its Accumulation at $41.03. Elevated stress, defensive posture warranted, held for 12 days.

As held on the ledger · 2026-07-19
PhaseAccumulation
Quantitative stateElevated stress, defensive posture warranted, held for 12 days
Price at the screen$41.03
Valuation38.35 trailing · -130.55 forward price to earnings
Values screenPASS · score 93.6
Beta-0.25
The Workings

Five Screens, Shown in Full

Full pass across all five screens. This security clears the Titan Ethical Standard: its business and its balance sheet both stay inside the lines.

TestFigureLimitWhat it meansStatus
Business activity Permissible Core business clean Its core business isn't built on prohibited lines: no gambling, alcohol, tobacco, weapons, or interest-based lending. Pass
Debt load 9.06% Below 33% Interest-bearing debt is just 9.1% of its assets, well under the one-third ceiling: it does not run on borrowed money. Pass
Interest-bearing cash 7.73% Below 33% Cash held in interest-bearing accounts and securities is 7.7% of assets, under the one-third limit. Pass
Receivables 0.00% Below 49% Money owed to the company is 0.0% of assets, under the 49% limit. Pass
Revenue purity 0.00% Below 5% Only 0.0% of revenue comes from non-compliant sources, under the 5% line. Pass

Five checks adapted from AAOIFI screening standards: business activity plus four balance-sheet ratios. All five must pass for ethical clearance. Every figure is arithmetic on public accounts, not judgement.

What the Numbers Say It Is Worth

The Fair Value Range

Our framework reads FAIR VALUE: it trades above our $41.00 fair value estimate, 60.90% revenue growth.

40.00Conservative41.00Base case41.00Growth case 41.03Price

Fair value range in USD, drawn from the 2026-07-19 screen. The gold marker is the market price at the same screen. The price runs 0.1% above the base estimate.

The Street's Range
40.00Street low 41.00Street average 41.00Street high 41.03Price

Third-party analyst targets: 13 covering, consensus Hold. The average target sits −0% from the screen price.

Reading the gap · Our model and the Street both land near today's price: fairly valued, with no strong edge either way.

Price History & Projections
$93.4$52.0$10.7TODAY5y agoPROJECTIONStreet avg$41.00 -0%Our fair value$41.00 -0%Street high$41.00 -0%Conservative$40.00 -3%

Where it has been, where the models see it going. History from market close data; projection points are our fair-value estimates and third-party analyst targets, dated to the 2026-07-19 screen.

Fair value and rating are our own model estimates; the Street's range reflects third-party analyst estimates. Analysis, not advice.

The Business, in Plain Words

Biotech firm priced exactly at fair value

Picture a commercial-stage drug maker finally turning high unmet needs into real sales. Apellis has delivered 61% revenue growth and a 12% profit margin while posting a striking 46% return on equity. Those numbers explain why the shares sit right at our calculated fair value with zero margin of safety.

The business clears our ethical screen and the analyst consensus lines up with a hold rating and a median target matching the current price. Forward earnings are still negative, however, so the strong recent profitability has yet to translate into sustained positive forecasts.

Risk sits in the usual biotech uncertainties around future trial outcomes and reimbursement, plus the fact that a negative forward multiple leaves little room for disappointment. The market is not offering a bargain or a clear overvaluation at these levels. Analysis, not advice.

The fundamentals · plain-English read
Forward P/E-130.5x
Trailing P/E38.3xexpensive: the price assumes strong growth ahead
EPS, trailing1.07
EPS, forward-0.40
Revenue growth+60.9%growing very fast
Profit margin12.1%thin but positive margins
Return on equity46.0%an exceptional return on shareholder capital
FCF yield-1.21%
Debt to equity1.15a meaningful debt load worth watching
Current ratio3.63comfortably covers its short-term bills
Beta-0.25barely tracks the market's swings
Short interest, float0.13%
52-week range16.61 - 41.14
Market cap$5.3B
Employees733

The risks · The things to watch: as a biotechnology name, trial and regulatory outcomes can move it sharply either way.

Plain-English interpretation of our own screen data. Analysis, not advice.

Titan Case Study

Our full written analysis of APLS: APLS Case Study → 2026-07-02

Where & How to Trade

APLS trades on Nasdaq. As a listed security it is accessible through almost any international broker offering its home market. New to this, or investing from abroad? Our guide to accessing global markets covers brokers, currencies and the practical steps.

The Dated Journal · Newest First, Never Edited

Every Entry, As Written

2026-08-21 Accumulation $41.03 +0.0% Entry 6

The framework reads accumulation. Smart money appears to be quietly building positions. This typically precedes a markup phase. Price has moved down 0.0% since our last review. Ethical screening: PASS with near-perfect ethical score. The risk-adjusted return profile shows modest positive risk-adjusted returns. Our composite framework grades it B, carrying a low risk profile. Technically it is holding around 57% above its long-term trend line with momentum reading neutral. Over the past year the shares are up 151%. Our forward projection puts the odds of a 10% gain over the next month near 32%. The street (13 analysts) rates it hold, with a mean price target of $41.

2026-07-21 Accumulation $41.03 +0.0% Entry 5

The framework reads accumulation. Smart money appears to be quietly building positions. This typically precedes a markup phase. Price has moved down 0.0% since our last review. Ethical screening: PASS with near-perfect ethical score. The risk-adjusted return profile shows modest positive risk-adjusted returns. Our composite framework grades it B, carrying a low risk profile. Technically it is holding around 57% above its long-term trend line with momentum reading neutral. Over the past year the shares are up 151%. Our forward projection puts the odds of a 10% gain over the next month near 32%. The street (13 analysts) rates it hold, with a mean price target of $41.

2026-07-18 Accumulation $41.03 +0.0% Entry 4

The framework reads accumulation. Smart money appears to be quietly building positions. This typically precedes a markup phase. Price has moved down 0.0% since our last review. Ethical screening: PASS with near-perfect ethical score. The risk-adjusted return profile shows modest positive risk-adjusted returns. Our composite framework grades it B, carrying a low risk profile. Technically it is holding around 57% above its long-term trend line with momentum reading neutral. Over the past year the shares are up 151%. Our forward projection puts the odds of a 10% gain over the next month near 32%. The street (13 analysts) rates it hold, with a mean price target of $41.

2026-07-17 Accumulation $41.03 +0.0% Entry 3

The framework reads accumulation. Smart money appears to be quietly building positions. This typically precedes a markup phase. Price has moved down 0.0% since our last review. Ethical screening: PASS with near-perfect ethical score (94). The risk-adjusted return profile shows modest positive risk-adjusted returns. Our composite framework grades it B, carrying a low risk profile. Technically it is holding around 57% above its long-term trend line with momentum reading neutral. Over the past year the shares are up 151%. Our forward projection puts the odds of a 10% gain over the next month near 32%. The street (13 analysts) rates it hold, with a mean price target of $41.

2026-07-03 Accumulation $41.03 +0.0% Entry 2

The framework reads accumulation. Smart money appears to be quietly building positions. This typically precedes a markup phase. Price has moved down 0.0% since our last review. Ethical screening: PASS with near-perfect ethical score (94). The risk-adjusted return profile shows modest positive risk-adjusted returns.

2026-07-02 Accumulation $41.03 Entry 1

The framework reads accumulation. Smart money appears to be quietly building positions. This typically precedes a markup phase. Ethical screening: PASS with near-perfect ethical score (94). The risk-adjusted return profile shows modest positive risk-adjusted returns.

Each entry above was written on its date, before the outcome. A journal you can prune is not a journal.

Related Securities · Others in APLS's Space

Screened names in the same industry · explore each on its own page.

The Insider Ledger · Form 4 Filings, As Filed
Most recent filings · APLS
DateInsiderTitleTypeSharesValue
2026-04-29 BAUMAL CAROLINE Officer 900 ·
2026-04-17 SULLIVAN TIMOTHY EUGENE Chief Financial Officer 11,096 ·
2026-03-11 FRANCOIS CEDRIC Chief Executive Officer 64,869 ·
2026-02-27 DOLSTEN MIKAEL G Director 14,312 ·
2026-02-11 DELONG MARK JEFFREY Officer 368 $8,153
2026-02-03 FRANCOIS CEDRIC Chief Executive Officer 8,840 $33,238
2026-01-28 NICHOLSON NUR Chief Technology Officer 45,220 ·
2026-01-28 CHOPAS JAMES GEORGE Officer 16,150 ·
2026-01-28 DELONG MARK JEFFREY Officer 36,606 ·
2026-01-28 BOUCHER KELLEY Officer 30,146 ·

Public filings, recorded as found. The full tape lives at Insider Intelligence.

What Holding Actually Paid · Price Plus Dividends
If $1,000 had been placed · historical, not a promise
PeriodPrice thenPrice returnDivs per share$1,000 becameTotal return
1 month $40.85 +0.5% · $1,005 +0.5%
2 months $18.87 +117.4% · $2,174 +117.4%
3 months $21.70 +89.1% · $1,891 +89.1%
6 months $20.33 +101.8% · $2,018 +101.8%
1 year $16.36 +150.8% · $2,508 +150.8%
2 years $41.92 -2.1% · $979 -2.1%
3 years $87.68 -53.2% · $468 -53.2%
5 years $44.26 -7.3% · $927 -7.3%

Historical returns from market close data. Past performance does not guarantee future results.

The Ledger's Promise

This entry now belongs to the ledger. Whatever APLS does next, these words stay.

Apellis Pharmaceuticals, Inc. · APLS · Accumulation · $41.03
Recorded 2026-07-19 · before the outcome · scored mechanically

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