APLS
Apellis Pharmaceuticals, Inc.
Healthcare · Biotechnology · NMS
$41.03
Close 2026-05-15
✓ ETHICAL PASS
HIGH
Data Confidence: 100%
Full financial profile available
Market Cap
$5.3B
Trailing P/E
38.35
Forward P/E
-120.68
Rev Growth
+60.9%
Profit Margin
12.1%
ROE
46.0%
Analyst Target
$40.92
Recommendation
HOLD
About Apellis Pharmaceuticals, Inc.

Apellis Pharmaceuticals, Inc., a commercial-stage biopharmaceutical company, focuses on the discovery, development, and commercialization of novel therapeutic compounds to treat diseases with high unmet needs. It offers EMPAVELI for the treatment of paroxysmal nocturnal hemoglobinuria; and SYFOVRE for treating geographic atrophy secondary to age-related macular degeneration and geographic atrophy (GA). The company also develops EMPAVELI to treat C3 glomerulopathy and immune complex membranoproliferative glomerulonephritis, focal segmental glomerulosclerosis, and delayed graft function; and APL-3007, a small interfering RNA, or siRNA for the treatment of GA. In addition, it conducts preclinical studies for APL-9099, a treatment targeting the neonatal Fc receptor, or FcRn, which has the potential to be a first-in-class gene editing treatment for future target indications with one-time dosing; and developing other programs with its proprietary in-house capabilities and under its Beam collaboration. It has a collaboration and license agreement with Swedish Orphan Biovitrum AB (publ) for development and commercialization of pegcetacoplan; and a collaboration with Beam Therapeutics, Inc. focused on the use of Beam's base editing technology to discover new treatments for complement-driven diseases. Apellis Pharmaceuticals, Inc. was incorporated in 2009 and is headquartered in Waltham, Massachusetts. As of May 14, 2026, Apellis Pharmaceuticals, Inc. operates as a subsidiary of Biogen Inc.

Opportunity Summary
Passes all ethical screens. Ranks better than 86% of screened stocks.
Ethical Screen
Business ActivityPASS
Debt Ratio (0.09%)PASS
Cash Ratio (0.08%)PASS
Receivables Ratio (0.00%)PASS
Revenue Ratio (0.00%)PASS
OverallPASS
Score Ethical: 93.6
Score Valuation: 33.0
Score Quality: 85.0
Score Combined: 58.7
· Tier: FAIR VALUE

Full Analysis

Opportunity scores, earnings history, insider transactions, institutional holders, analyst consensus, and more.

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Opportunity Scores
Valuation43.0
Quality86.2
Cash Flow50.0
Moat50.0
Balance Sheet58.8
Debt Purity72.6
Liquid Purity76.6
Rev Purity100.0
Compliance81.8
Tier: BRONZE · Score: 55.0 · Rank: #869
Earnings History (Last 8 Quarters)
DateEPS Est.Reported EPSSurprise %
2026-07-30-0.33Pending--
2026-05-07-0.360.15+141.3%
2026-02-24-0.39-0.47-19.4%
2025-10-300.941.67+77.3%
2025-07-31-0.47-0.33+29.8%
2025-05-07-0.35-0.74-114.4%
2025-02-28-0.41-0.29+29.3%
2024-11-05-0.27-0.46-71.4%
Quarterly Financials
PeriodRevenueNet IncomeEBITDAGross ProfitOp. IncomeEPS
2026-03-31$268.3M$18.7M$29.8M$227.7M$26.5M0.15
2025-12-31$199.9M-$59.0M-$47.5M$170.2M-$51.1M
2025-09-30$458.6M$215.7M$227.9M$434.0M$223.2M1.71
2025-06-30$178.5M-$42.2M-$30.1M$164.9M-$33.3M-0.33
2025-03-31$166.8M-$92.2M-$80.4M$132.4M-$83.3M-0.74
2024-12-31
Insider Transactions
DateNameRoleSharesValue
2026-04-29BAUMAL CAROLINEOfficer900--
2026-04-17SULLIVAN TIMOTHY EUGENEChief Financial Officer11,096--
2026-03-11FRANCOIS CEDRICChief Executive Officer64,869--
2026-02-27DOLSTEN MIKAEL GDirector14,312--
2026-02-11DELONG MARK JEFFREYOfficer368$8.2K
2026-02-03FRANCOIS CEDRICChief Executive Officer8,840$33.2K
2026-01-28NICHOLSON NURChief Technology Officer45,220--
2026-01-28CHOPAS JAMES GEORGEOfficer16,150--
2026-01-28DELONG MARK JEFFREYOfficer36,606--
2026-01-28BOUCHER KELLEYOfficer30,146--
Top Institutional Holders
HolderSharesValue% Held
Blackrock Inc.13.5M$555.4M0.1%
Wellington Management Group, LLP12.7M$522.0M0.1%
Avoro Capital Advisors LLC12.2M$501.5M0.1%
Morgan Stanley9.2M$376.4M0.1%
Deep Track Capital, Lp7.8M$318.0M0.1%
RTW Investments LP7.7M$314.6M0.1%
UBS Group AG6.2M$254.7M0.0%
Vanguard Portfolio Management LLC5.4M$221.7M0.0%
Vanguard Capital Management LLC4.8M$195.7M0.0%
State Street Corporation4.6M$189.3M0.0%
Analyst Recommendations
3 Months Ago
1
19
20 analysts
2 Months Ago
2
5
13
20 analysts
Last Month
3
11
7
22 analysts
Current
1
15
16 analysts
Strong Buy Buy Hold Sell Strong Sell
Additional Fundamentals
Enterprise Value
$5.3B
Price/Book
12.65
Beta
-0.246
Analysts
13
Total Revenue (TTM)
$1.1B
Total Debt
$475.8M
Rec. Mean
2.88
Short Ratio
1.15
Short % Float
0.1%
Employees
733

Elite Intelligence

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Trade Consideration
The Opportunity
Score 58.7 (P93 — top 6.7% of scored tickers). Ethical PASS. 13 analysts at Hold.
Price: $41.03 | Target: $40.92 (+-0%)
Score
59
Moat
Conviction
Standard
Upside
+-0%
The Fundamentals
Revenue Growth+60.9%
Profit Margin12.1%
ROE46.0%
Forward P/E-120.7
Market Cap$5.3B
Earnings Track Record
DateEstimateReportedSurprise
2026-07-30$-0.33Pending
2026-05-07$-0.36$0.15+141.3%
2026-02-24$-0.39$-0.47-19.4%
2025-10-30$0.94$1.67+77.3%
2025-07-31$-0.47$-0.33+29.8%
2025-05-07$-0.35$-0.74-114.4%
Position Sizing Scenarios
Stop: $34.88 (-15%) | Entry: $41.03
SharesCostProfit to TargetR:R
To Consensus ($40.92, 13 analysts)
10$410.30+$-1.10 (-0%)-0.0R
50$2,051.50+$-5.50 (-0%)-0.0R
100$4,103.00+$-11.00 (-0%)-0.0R
Risk Factors
  • No elevated risk flags in current data
The Verdict
Apellis Pharmaceuticals, Inc. passes all ethical screens and is growing revenue at +60.9%.
Quantitative Grade

A single score combining all analytical layers below. A is strongest, D is weakest.

B
Quant Score
56.4
Risk Grade
LOW_RISK
Layers
8
Quality: HMM_CRISIS,STRONG_EARNINGS_DRIFT
Risk Profile

How much could this ticker lose on a bad day? These metrics measure worst-case scenarios from historical data.

VaR 95%
-4.4%
worst expected daily loss, 19 in 20 days
CVaR 95%
-8.8%
avg loss on the worst 5% of days
Annual Volatility
Sortino Ratio
0.01
above 1.0 is good
Max Drawdown
-61.7%
Worst Day
Forward Outlook

Based on 10,000 simulated price paths, here is the probability of where this ticker could be in 30, 60, and 90 days.

30d Prob Up
90d Prob Up
Median Return 30d
Liquidity Score
80
Liquidity Grade
HIGHLY LIQUID
Trend & Momentum

What direction is this ticker actually moving, filtered through noise? Is it speeding up or slowing down?

Kalman Trend
Trend Strength
Momentum Signal
HMM Regime
RSI Signal
Technical Signals

Classic chart signals that institutional traders monitor. Golden Cross is bullish, Death Cross is bearish.

MA Crossover
ABOVE_200
Bollinger Position
UPPER_HALF
Beta
Relative Volume
0.4x
Short Interest
Financial Health

Is this company financially sound? The Z-Score measures bankruptcy risk. The F-Score measures fundamental strength.

Altman Z-Score
below 1.81 = distress zone
Piotroski F-Score
Earnings Beat Rate
62.5%
Earnings Consistency
Correlations

These tickers tend to move together (positive) or in opposite directions (negative). Useful for portfolio diversification.

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Inverse Correlated
TickerCorrelation
CBNT-0.236
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BCFC.BH-0.217
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Seasonality

Does this ticker have consistent patterns on certain days or months? Historical tendencies, not guarantees.

Best Day
Tuesday
Worst Day
Friday
Best Month
Mar
Worst Month
Sep
Fri-Mon Effect
-0.3741042974292918
Earnings Drift

After this company beats earnings, does the price keep going up? Drift tracks post-earnings momentum.

Avg Drift After Beat
+8.1%
Beat Drift Positive %
75.0%
Consistency
Momentum Rankings

How does this ticker's recent performance compare to the entire universe? Ranked across 1, 3, 6, and 12-month returns.

1M Return
+0.4%
3M Return
+89.1%
6M Return
+105.0%
12M Return
+145.7%
Momentum Rank
#212
Momentum Signal
STRONG_UP

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