The framework reads accumulation. Smart money appears to be quietly building positions. This typically precedes a markup phase. Price has moved down 5.4% since our last review. Ethical screening: PASS with passing ethical screen. The risk-adjusted return profile shows good risk-adjusted returns. Our composite framework grades it C, carrying a low risk profile. Technically it is sitting below its long-term trend line with momentum reading bullish. Over the past year the shares are down 3%. Our forward projection puts the odds of a 10% gain over the next month near 33%. The street (25 analysts) rates it buy, with a mean price target of $439.
Alnylam Pharmaceuticals Inc ALNY
Clears both ethical standards
An entry written while the outcome is still unknown. It will be scored by what the market does next, and it will never be edited to look cleverer than it was.
In plain words · Alnylam Pharmaceuticals, Inc.
read at $278.40
Alnylam Pharmaceuticals Inc holds its Distribution at $278.40.
- PHPhase · the trend structure carries the Distribution label
- INInsiders · no filings inside 60 days, left as found
- POPositioning · no disclosures inside 60 days, left as found
- OPOptions · no verdict drawn today, left as found
- SCScreen · passes the values gate
- edge confirmed
- edge broken
- edge forming
Each arm is one independent read. Conviction is not a single call, it is how many edges converge.
The investor read · the season, not the day
| Phase | Distribution · caution |
| Quantitative state | The statistical read favours the sellers, held for 213 days |
| Price | $278.40 |
| Valuation | 70.13 trailing · 20.71 forward price to earnings |
| Values screen | PASS · score 70.0 |
| Beta | 0.27 |
The opportunity · what the numbers say it is worth
Price history & projections · where it has been, where the models see it going
The valuation journey · where the price sits against fair value and the Street
Green marks levels above today's price, red below; the shaded band is the gap between the price and our fair value.
Reading the gap · Both our model and the analysts see meaningful upside from here.
| Revenue growth | 96.40% |
| Profit margin | 12.55% |
| Debt to equity | 276.20 |
| Analyst consensus | Buy · 23 covering |
Fair value and rating are our own model estimates; target range reflects third-party analyst estimates. Analysis, not advice.
The values screen, explained · five checks, plain English
This company clears both standards. There are two widely recognised ways to check whether a company is suitable for a Muslim investor. Here is how it did on each:
Used by most halal investing apps ✓ PASSES
The one Titan applies ✓ PASSES
What these two standards are, and how they differ →
- Business activity Its core business isn't built on prohibited lines — no gambling, alcohol, tobacco, weapons, or interest-based lending. Pass
- Debt load Interest-bearing debt is of its assets, above the one-third ceiling the screen allows. Fail
- Interest-bearing cash Interest-bearing cash and securities are of assets, above the one-third limit. Fail
- Receivables Money owed to the company is of assets, above the 49% limit. Fail
- Revenue purity of revenue comes from non-compliant sources, over the 5% line. Fail
Every security is read against two recognised standards: our stricter asset-based screen (ratios measured against total assets) and the more widely used market-value standard (measured against market capitalisation). Where they agree we say so plainly; where they part ways — almost always on the debt check — we show both readings and mark it, because that disagreement is the finding, not a fault. We report the score; you and your scholar make the call.
The business, in plain words · what the numbers mean
Gene Silencing Drugs Face Narrow Moat Limits
Picture a treatment that turns off faulty genes before they trigger rare diseases. Alnylam has turned that idea into products such as ONPATTRO and AMVUTTRA, driving 96% revenue growth and a 90% return on equity. Yet the opportunity rating sits at none, so we pass despite a 35% gap between the $267 share price and our $360 fair value.
Forward earnings sit at 20 times, margins have reached 13%, and the narrow moat reflects real but limited protection in a crowded rare-disease field. Analyst targets cluster around $425 on a buy consensus, yet those forecasts rest on execution that remains unproven at scale.
The main risks are clinical setbacks, pricing pressure, and competition that could erode the current returns quickly. Currency and regulatory shifts add further volatility for a company still scaling commercial reach. Analysis, not advice.
| Forward P/E | 20.7x cheap for a company growing this fast |
| Trailing P/E | 70.1x expensive — the price assumes strong growth ahead |
| Revenue growth | 96.4% growing very fast |
| Profit margin | 12.6% thin but positive margins |
| Return on equity | 90.4% an exceptional return on shareholder capital |
| Debt to equity | 2.76 heavy leverage — higher risk if revenue softens |
| Current ratio | 3.13 comfortably covers its short-term bills |
| Beta | 0.27 barely tracks the market's swings |
| Market cap | $37.2B |
| Employees | 2,500 |
The risks · The things to watch: as a biotechnology name, trial and regulatory outcomes can move it sharply either way; it carries a real debt load, which raises the stakes if revenue slips.
Plain-English interpretation of our own screen data. Analysis, not advice.
Latest news · what the market is reading on ALNY
- › Collect 9.8% On VRTX Stock Now, And Still Keep 15% Of Upside Trefis · 17d ago
- › Morgan Stanley Raises its Price Target on Alnylam (ALNY) Insider Monkey · 19d ago
- › Alnylam Pharmaceuticals' Q2 Results to Determine 2026 Revenue Outlook, BofA Securities Says MT Newswires · 19d ago
- › The Phase 3 Failure That Sent Biotech Winners and Losers in Opposite Directions MarketBeat · 20d ago
- › What It Means To Hold Moderna Stock In A Crash Trefis · 20d ago
Headlines from third-party outlets, linked for reference — not our reporting, not advice.
Related securities · others in ALNY's space worth a look
Screened names in the same industry · explore each on its own page.
The trader read · the latest dated commentary
The dated journal · newest first, never edited
The framework reads accumulation. Smart money appears to be quietly building positions. This typically precedes a markup phase. Price has moved down 0.0% since our last review. Ethical screening: PASS with passing ethical screen. The risk-adjusted return profile shows good risk-adjusted returns. Our composite framework grades it C, carrying a low risk profile. Technically it is sitting below its long-term trend line with momentum reading bullish. Over the past year the shares are down 3%. Our forward projection puts the odds of a 10% gain over the next month near 33%. The street (25 analysts) rates it buy, with a mean price target of $439.
The framework reads accumulation. Smart money appears to be quietly building positions. This typically precedes a markup phase. Price has moved down 0.0% since our last review. Ethical screening: PASS with passing ethical screen (70). The risk-adjusted return profile shows good risk-adjusted returns. Our composite framework grades it C, carrying a low risk profile. Technically it is sitting below its long-term trend line with momentum reading bullish. Over the past year the shares are down 3%. Our forward projection puts the odds of a 10% gain over the next month near 33%. The street (25 analysts) rates it buy, with a mean price target of $439.
The framework reads accumulation. Smart money appears to be quietly building positions. This typically precedes a markup phase. Price has moved down 0.0% since our last review. Ethical screening: PASS with passing ethical screen (70). The risk-adjusted return profile shows good risk-adjusted returns.
The framework reads accumulation. Smart money appears to be quietly building positions. This typically precedes a markup phase. Ethical screening: PASS with passing ethical screen (70). The risk-adjusted return profile shows good risk-adjusted returns.
Each entry above was written on its date, before the outcome. A journal you can prune is not a journal.
What holding actually paid · price plus dividends
| Period | Price then | Price return | Divs per share | $1,000 became | Total return |
|---|---|---|---|---|---|
| 1 month | $284.84 | +2.9% | · | $1,029 | +2.9% |
| 2 months | $322.11 | -9.0% | · | $910 | -9.0% |
| 3 months | $317.23 | -7.6% | · | $924 | -7.6% |
| 6 months | $412.63 | -29.0% | · | $710 | -29.0% |
| 1 year | $302.46 | -3.1% | · | $969 | -3.1% |
| 2 years | $153.47 | +90.9% | · | $1,909 | +90.9% |
| 3 years | $190.83 | +53.6% | · | $1,536 | +53.6% |
| 5 years | $165.02 | +77.6% | · | $1,776 | +77.6% |
Historical returns from market close data. Past performance does not guarantee future results.