The framework reads markup. Price is trending higher with momentum. The crowd has caught on and buyers are in control. Price has moved up 65.2% since our last review. Ethical screening: PASS with passing ethical screen. The risk-adjusted return profile shows modest positive risk-adjusted returns. Our composite framework grades it B. Technically it is holding around 51% above its long-term trend line with momentum reading overbought. Over the past year the shares are up 58%. Our forward projection puts the odds of a 10% gain over the next month near 27%. The street (10 analysts) rates it buy, with a mean price target of $9.
Iovance Biotherapeutics, Inc.
IOVA · Nasdaq · USD · Market cap $3.7B · 975 employees
Iovance Biotherapeutics, Inc., a commercial-stage biopharmaceutical company, develops and commercializes cell therapies using autologous tumor infiltrating lymphocyte for the treatment of metastatic melanoma and other so…
PASS · Titan Ethical · score 70.0At the last full screen
2026-08-27
Screened 2026-08-27 · the tape above runs as of 10:31 UTC · two dates, stated on purpose · verdict and workings shown in full · never trimmed
This name holds its markup label.
Iovance Biotherapeutics, Inc. holds its Markup at $8.26. Consolidating, no directional conviction, held for 17 days.
| Phase | Markup |
| Quantitative state | Consolidating, no directional conviction, held for 17 days |
| Price at the screen | $8.26 |
| Valuation | N/A trailing · -28.75 forward price to earnings |
| Values screen | PASS · score 70.0 |
| Beta | 0.70 |
Five Screens, Shown in Full
Full pass across all five screens. This security clears the Titan Ethical Standard: its business and its balance sheet both stay inside the lines.
| Test | Figure | Limit | What it means | Status |
|---|---|---|---|---|
| Business activity | Permissible | Core business clean | Its core business isn't built on prohibited lines: no gambling, alcohol, tobacco, weapons, or interest-based lending. | Pass |
| Debt load | 5.41% | Below 33% | Interest-bearing debt is just 5.4% of its assets, well under the one-third ceiling: it does not run on borrowed money. | Pass |
| Interest-bearing cash | 14.66% | Below 33% | Cash held in interest-bearing accounts and securities is 14.7% of assets, under the one-third limit. | Pass |
| Receivables | 26.89% | Below 49% | Money owed to the company is 26.9% of assets, under the 49% limit. | Pass |
| Revenue purity | 3.91% | Below 5% | Only 3.9% of revenue comes from non-compliant sources, under the 5% line. | Pass |
Five checks adapted from AAOIFI screening standards: business activity plus four balance-sheet ratios. All five must pass for ethical clearance. Every figure is arithmetic on public accounts, not judgement.
What the Numbers Say It Is WorthThe Fair Value Range
Fair value range in USD, drawn from the 2026-08-27 screen. The gold marker is the market price at the same screen. A 21.1% margin of safety to the base estimate.
Third-party analyst targets: 9 covering, consensus Buy. The average target sits +21% from the screen price.
Reading the gap · Both our model and the analysts see meaningful upside from here.
Price History & ProjectionsWhere it has been, where the models see it going. History from market close data; projection points are our fair-value estimates and third-party analyst targets, dated to the 2026-08-27 screen.
Fair value and rating are our own model estimates; the Street's range reflects third-party analyst estimates. Analysis, not advice.
The Business, in Plain WordsCell therapy hopes hit a wall of losses
When a patient waits for a last-line melanoma treatment, the promise of harvesting their own immune cells feels like genuine progress. Iovance is trying to turn that science into a repeatable commercial product across solid tumours.
Revenue is climbing at 45 percent, analysts see a path to roughly ten dollars, and the ethical screen is clear. Yet forward earnings sit at minus 15.7 times, profit margins are minus 124 percent, and return on equity is minus 48 percent. No identifiable moat and our opportunity rating is none.
The sector is littered with companies that grew fast then burned cash until dilution or failure arrived. Negative profitability at this scale leaves little room for execution slips or delayed approvals. Analysis, not advice.
| Forward P/E | -28.8x |
| EPS, trailing | -0.69 |
| EPS, forward | -0.29 |
| Revenue growth | +65.7%growing very fast |
| Profit margin | -89.1%currently unprofitable |
| Return on equity | -40.4%not currently earning a positive return on equity |
| FCF yield | -5.02% |
| Debt to equity | 0.06minimal debt: a conservative balance sheet |
| Current ratio | 4.35comfortably covers its short-term bills |
| Beta | 0.70steadier than the market |
| Short interest, float | 0.24% |
| 52-week range | 1.76 - 9.36 |
| Market cap | $3.7B |
| Employees | 975 |
The risks · The things to watch: as a biotechnology name, trial and regulatory outcomes can move it sharply either way.
Plain-English interpretation of our own screen data. Analysis, not advice.
Where & How to TradeIOVA trades on Nasdaq. As a listed security it is accessible through almost any international broker offering its home market. New to this, or investing from abroad? Our guide to accessing global markets covers brokers, currencies and the practical steps.
Every Entry, As Written
The framework reads markup. Price is trending higher with momentum. The crowd has caught on and buyers are in control. Price has moved up 22.5% since our last review. Ethical screening: PASS with passing ethical screen. The risk-adjusted return profile shows modest positive risk-adjusted returns. Our composite framework grades it B. Technically it is holding around 51% above its long-term trend line with momentum reading overbought. Over the past year the shares are up 58%. Our forward projection puts the odds of a 10% gain over the next month near 27%. The street (10 analysts) rates it buy, with a mean price target of $9.
The framework reads markup. Price is trending higher with momentum. The crowd has caught on and buyers are in control. Price has moved down 0.0% since our last review. Ethical screening: PASS with passing ethical screen. The risk-adjusted return profile shows modest positive risk-adjusted returns. Our composite framework grades it B. Technically it is holding around 51% above its long-term trend line with momentum reading overbought. Over the past year the shares are up 58%. Our forward projection puts the odds of a 10% gain over the next month near 27%. The street (10 analysts) rates it buy, with a mean price target of $9.
The framework reads markup. Price is trending higher with momentum. The crowd has caught on and buyers are in control. Price has moved down 0.0% since our last review. Ethical screening: PASS with passing ethical screen (70). The risk-adjusted return profile shows modest positive risk-adjusted returns.
The framework reads markup. Price is trending higher with momentum. The crowd has caught on and buyers are in control. Ethical screening: PASS with passing ethical screen (70). The risk-adjusted return profile shows modest positive risk-adjusted returns.
Each entry above was written on its date, before the outcome. A journal you can prune is not a journal.
Screened names in the same industry · explore each on its own page.
| Period | Price then | Price return | Divs per share | $1,000 became | Total return |
|---|---|---|---|---|---|
| 1 month | $3.70 | +1.9% | · | $1,019 | +1.9% |
| 2 months | $3.70 | +1.9% | · | $1,019 | +1.9% |
| 3 months | $4.07 | -7.4% | · | $926 | -7.4% |
| 6 months | $2.25 | +67.6% | · | $1,676 | +67.6% |
| 1 year | $2.38 | +58.4% | · | $1,584 | +58.4% |
| 2 years | $8.06 | -53.2% | · | $468 | -53.2% |
| 3 years | $7.89 | -52.2% | · | $478 | -52.2% |
| 5 years | $23.45 | -83.9% | · | $161 | -83.9% |
Historical returns from market close data. Past performance does not guarantee future results.
This entry now belongs to the ledger. Whatever IOVA does next, these words stay.
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Join the deskScreening is research, not a fatwa and not financial advice. Figures are drawn from public accounts at the screen date shown. Always manage your risk.