IOVA
Iovance Biotherapeutics, Inc.
Healthcare · Biotechnology · NGM
$4.37
Close 2026-05-28
✓ ETHICAL PASS

UNKNOWN MOAT
HIGH
Data Confidence: 86%
Full financial profile available
Market Cap
$2.0B
Trailing P/E
Forward P/E
-13.69
Rev Growth
+44.8%
Profit Margin
-123.9%
ROE
-47.5%
Analyst Target
$9.50
Recommendation
BUY
About Iovance Biotherapeutics, Inc.

Iovance Biotherapeutics, Inc., a commercial-stage biopharmaceutical company, develops and commercializes cell therapies using autologous tumor infiltrating lymphocyte for the treatment of metastatic melanoma and other solid tumor cancers in the United States and internationally. The company offers Amtagvi, an individualized T cell therapy for solid tumor cancer and for the treatment of adult patients with previously treated advanced, or unresectable or metastatic melanomal; and Proleukin, an interleukin-2 product for the treatment of patients with metastatic melanoma and metastatic renal cell carcinoma. It also develops lifileucel for the treatment of melanoma, cervical cancer, non-small cell lung cancer (NSCLC), endometrial cancer, and head and neck squamous cell carcinoma (HNSCC); LN-145-S1 to treat melanoma and HNSCC; LN-145 Gen 3 and core biopsy for the treatment of NSCLC; LN-145 Gen 3 to treat melanoma and HNSCC; IOV-2001 to treat chronic lymphocytic leukemia and small lymphocytic lymphoma; IOV-4001 for the treatment of melanoma and NSCLC; and IOV-3001 for use in the TIL therapy treatment regimen. The company has collaborations and licensing agreements with National Institutes of Health; the National Cancer Institute; Cellectis S.A.; Novartis Pharma AG; and Boehringer Ingelheim Biopharmaceuticals GmbH. The company was formerly known as Lion Biotechnologies, Inc. and changed its name to Iovance Biotherapeutics, Inc. in June 2017. Iovance Biotherapeutics, Inc. was incorporated in 2007 and is headquartered in San Carlos, California.

Ethical Screen
Business ActivityPASS
Debt RatioN/A
Cash RatioN/A
Receivables RatioN/A
Revenue Ratio (0.00%)PASS
OverallPASS
Score Ethical: 64.7
Score Valuation: 33.0
Score Quality: 33.8
Score Combined: 37.8

Full Analysis

Opportunity scores, earnings history, insider transactions, institutional holders, analyst consensus, and more.

Unlock with Membership
Opportunity Scores
Valuation50.0
Quality25.0
Cash Flow0.0
Moat40.0
Balance Sheet0.0
Debt Purity50.0
Liquid Purity50.0
Rev Purity100.0
Compliance100.0
Tier: WATCH · Score: 37.4 · Rank: #4535
Insider Transactions
No insider transaction data.
Top Institutional Holders
No institutional holder data.
Additional Fundamentals
Enterprise Value
$1.7B
Price/Book
2.61
Beta
0.688
Analysts
10
Total Revenue (TTM)
$285.6M
Total Debt
$47.8M
Rec. Mean
1.60
Short Ratio
7.03
Short % Float
0.3%
Employees
975

Elite Intelligence

Trade Consideration with position sizing, convergence signals, and risk analysis. Available to Elite members.

Upgrade to Elite
Trade Consideration
The Opportunity
Score 37.8 (P39 — top 60.9% of scored tickers). Unknown Moat. Ethical PASS. 10 analysts at Buy.
Price: $4.37 | Target: $8.80 (+101%)
Score
38
Moat
Unknown
Conviction
Standard
Upside
+101%
The Fundamentals
Revenue Growth+44.8%
Profit Margin-123.9%
ROE-47.5%
Forward P/E-13.7
Market Cap$2.0B
Position Sizing Scenarios
Stop: $3.71 (-15%) | Entry: $4.37
SharesCostProfit to TargetR:R
To Consensus ($8.80, 10 analysts)
10$43.70+$44.30 (101%)6.7R
50$218.50+$221.50 (101%)6.7R
100$437.00+$443.00 (101%)6.7R
Risk Factors
  • Elevated short interest (7.03 days to cover)
The Verdict
Iovance Biotherapeutics, Inc. passes all ethical screens, holds a unknown competitive moat, and is growing revenue at +44.8%.
Quantitative Grade

A single score combining all analytical layers below. A is strongest, D is weakest.

B
Quant Score
67.2
Risk Grade
Layers
7
Risk Profile

How much could this ticker lose on a bad day? These metrics measure worst-case scenarios from historical data.

VaR 95%
-7.5%
worst expected daily loss, 19 in 20 days
CVaR 95%
-12.9%
avg loss on the worst 5% of days
Annual Volatility
Sortino Ratio
-0.51
above 1.0 is good
Max Drawdown
-86.5%
Worst Day
Forward Outlook

Based on 10,000 simulated price paths, here is the probability of where this ticker could be in 30, 60, and 90 days.

30d Prob Up
90d Prob Up
Median Return 30d
Liquidity Score
70
Liquidity Grade
LIQUID
Trend & Momentum

What direction is this ticker actually moving, filtered through noise? Is it speeding up or slowing down?

Kalman Trend
Trend Strength
Momentum Signal
HMM Regime
RSI Signal
Technical Signals

Classic chart signals that institutional traders monitor. Golden Cross is bullish, Death Cross is bearish.

MA Crossover
ABOVE_200
Bollinger Position
NEAR_UPPER
Beta
Relative Volume
0.9x
Short Interest
Financial Health

Is this company financially sound? The Z-Score measures bankruptcy risk. The F-Score measures fundamental strength.

Altman Z-Score
below 1.81 = distress zone
Piotroski F-Score
Earnings Beat Rate
Earnings Consistency
Correlations

These tickers tend to move together (positive) or in opposite directions (negative). Useful for portfolio diversification.

Most Correlated
TickerCorrelation
ARKG0.432
CLDX0.409
DNLI0.388
CRSP0.378
XNCR0.378
Inverse Correlated
TickerCorrelation
KYIVW-0.130
FAREAST.KL-0.125
4337.SR-0.123
NAHO.AE-0.119
BAES.L-0.117
Seasonality

Does this ticker have consistent patterns on certain days or months? Historical tendencies, not guarantees.

Best Day
Wednesday
Worst Day
Friday
Best Month
Jul
Worst Month
May
Fri-Mon Effect
-0.9712245236536649
Momentum Rankings

How does this ticker's recent performance compare to the entire universe? Ranked across 1, 3, 6, and 12-month returns.

1M Return
+27.2%
3M Return
+13.5%
6M Return
+72.0%
12M Return
+148.6%
Momentum Rank
#341
Momentum Signal
STRONG_UP

Get our daily market read free. Join thousands of traders.

Free Explorer Access