The analysis reads markdown. Price is trending lower. Sellers are in control and the prior trend has reversed. Price has moved up 12.0% since our last review. Ethical screening: PASS with passing ethical screen. The risk-adjusted return profile shows modest positive risk-adjusted returns. Our composite framework grades it C. Technically it is holding around 32% above its long-term trend line with momentum reading oversold. Over the past year the shares are up 67%. Our forward projection puts the odds of a 10% gain over the next month near 44%. The street (7 analysts) rates it strong buy, with a mean price target of $20. Insiders have been net sellers over the past quarter. It reported earnings in this window, a natural checkpoint for the thesis.
Adaptive Biotechnologies Corporation
ADPT · Nasdaq · USD · Market cap $4.0B · 624 employees
Adaptive Biotechnologies Corporation, a commercial-stage company, develops an immune medicine platform for the diagnosis and treatment of various diseases.
PASS · Titan Ethical · score 70.0Price as of 28 Oct 2026Daily close, not a live quote
Screened 2026-10-28 · the tape above runs as of 18:02 UTC · two dates, stated on purpose · verdict and workings shown in full · never trimmed
Key facts today
- Price28.37 USD at the 28 Oct 2026 close
- Ethical screenPasses, score 70.0 out of 100
- OptionsOpen interest leans heavily to calls (put/call 0.08)
- Last reviewed28 Oct 2026 (1 days ago)
A summary of the dated readings below, not a live quote and not advice.
What this means: price 28.37 against the desk's fair-value range, base estimate 31.00, over the last year.
- Trend Markdown
- Insiders insiders sold, $897,457, latest filing 2026-10-22
- Positioning no disclosures inside 60 days, left as found
- Options put/call open interest 0.08, read 2026-10-28
- Ethical passes the values gate
Our analytic regime reads on this name, dated and marked against the screened price. Small sample per name, and separate from the daily-framework accuracy on the Track Record page.
This name holds its markdown label.
Adaptive Biotechnologies Corporation holds its Markdown at $28.37. Elevated stress, defensive posture warranted, held for 13 days.
| Phase | Markdown · caution |
| Quantitative state | Elevated stress, defensive posture warranted, held for 13 days |
| Price at the screen | $28.37 |
| Valuation | N/A trailing · -140.50 forward price to earnings |
| Values screen | PASS · score 70.0 |
| Beta | 2.10 |
Five Screens, Shown in Full
Full pass across all five screens. This security clears the Titan Ethical Standard: its business and its balance sheet both stay inside the lines.
| Test | Figure | Limit | What it means | Status |
|---|---|---|---|---|
| Business activity | Permissible | Core business clean | Its core business isn't built on prohibited lines: no gambling, alcohol, tobacco, weapons, or interest-based lending. | Pass |
| Debt load | 15.44% | Below 33% | Interest-bearing debt is just 15.4% of its assets, well under the one-third ceiling: it does not run on borrowed money. | Pass |
| Interest-bearing cash | 2.58% | Below 33% | Cash held in interest-bearing accounts and securities is 2.6% of assets, under the one-third limit. | Pass |
| Receivables | 23.57% | Below 49% | Money owed to the company is 23.6% of assets, under the 49% limit. | Pass |
| Revenue purity | 3.41% | Below 5% | Only 3.4% of revenue comes from non-compliant sources, under the 5% line. | Pass |
Five checks adapted from AAOIFI screening standards: business activity plus four balance-sheet ratios. All five must pass for ethical clearance. Every figure is arithmetic on public accounts, not judgement.
The Ethical ReadWhy It Clears, in Plain English
Adaptive Biotechnologies clears all five screens. Its business is in a permissible area, its interest-bearing debt is about 15%, inside the ~33% line, and interest is about 3% of its income, under the ~5% line, so it passes.
Read as at 2026-10-28. It updates when the underlying figures move, and past reads are kept below.
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The Fair Value Range
Fair value range in USD, drawn from the 2026-10-28 screen. The gold marker is the market price at the same screen. A 9.3% margin of safety to the base estimate.
Third-party analyst targets: 8 covering, consensus Strong Buy. The average target sits +9% from the screen price.
Reading the gap · Both our model and the analysts see meaningful upside from here.
Price History & ProjectionsWhere it has been, where the models see it going. History from market close data; projection points are our fair-value estimates and third-party analyst targets, dated to the 2026-10-28 screen.
Fair value and rating are our own model estimates; the Street's range reflects third-party analyst estimates. Analysis, not advice.
The Business, in Plain WordsImmune sequencing bets still lose cash at scale
Every new immune test that gets ordered in a hospital lab adds another line of revenue for Adaptive Biotechnologies, yet the company still burns cash on every sale. Revenue is growing at 35 percent, which sounds promising for a commercial-stage diagnostics platform, but forward earnings sit at minus 96.7 times sales and profit margins remain negative 17 percent.
We pass because the numbers do not support ownership at current prices. The stock trades above our fair value with a negative margin of safety, return on equity is minus 24 percent, and no economic moat is visible. Analyst targets cluster around the present quote, offering no cushion against further dilution or slower test adoption.
Risk sits with execution and cash burn in a market that already prices in strong buy ratings. Losses could widen if clinical uptake stalls, and the ethical screen offers no offset for the weak financial profile. Analysis, not advice.
| Forward P/E | -140.5x |
| EPS, trailing | -0.41 |
| EPS, forward | -0.18 |
| Revenue growth | +21.5%strong top-line growth |
| Profit margin | -20.7%currently unprofitable |
| Return on equity | -38.8%not currently earning a positive return on equity |
| FCF yield | 0.47% |
| Debt to equity | 2.72heavy leverage: higher risk if revenue softens |
| Current ratio | 4.80comfortably covers its short-term bills |
| Beta | 2.10much more volatile than the market |
| Short interest, float | 0.09% |
| 52-week range | 12.00 - 30.74 |
| Market cap | $4.0B |
| Employees | 624 |
The risks · The things to watch: it already moves more than the market on an average day; it carries a real debt load, which raises the stakes if revenue slips.
Plain-English interpretation of our own screen data. Analysis, not advice.
Where & How to TradeADPT trades on Nasdaq. As a listed security it is accessible through almost any international broker offering its home market. New to this, or investing from abroad? Our guide to accessing global markets covers brokers, currencies and the practical steps.
Every Entry, As Written
The analysis reads markdown. Price is trending lower. Sellers are in control and the prior trend has reversed. Price has moved down 0.0% since our last review. Ethical screening: PASS with passing ethical screen. The risk-adjusted return profile shows modest positive risk-adjusted returns. Our composite framework grades it C. Technically it is holding around 32% above its long-term trend line with momentum reading oversold. Over the past year the shares are up 67%. Our forward projection puts the odds of a 10% gain over the next month near 44%. The street (7 analysts) rates it strong buy, with a mean price target of $20. Insiders have been net sellers over the past quarter. It reported earnings in this window, a natural checkpoint for the thesis.
The analysis reads markdown. Price is trending lower. Sellers are in control and the prior trend has reversed. Price has moved down 1.0% since our last review. Ethical screening: PASS with passing ethical screen. The risk-adjusted return profile shows modest positive risk-adjusted returns. Our composite framework grades it D. Technically it is holding around 32% above its long-term trend line with momentum reading oversold. Over the past year the shares are up 67%. Our forward projection puts the odds of a 10% gain over the next month near 44%. The street (7 analysts) rates it strong buy, with a mean price target of $20. Insiders have been net sellers over the past quarter. Since the last review it its composite score rose.
The framework has shifted from accumulation to markdown since the last review. Price is trending lower. Sellers are in control and the prior trend has reversed. Price has moved down 3.4% since our last review. Ethical screening: PASS with passing ethical screen. The risk-adjusted return profile shows modest positive risk-adjusted returns. Our composite framework grades it C. Technically it is holding around 26% above its long-term trend line with momentum reading bearish. Over the past year the shares are up 67%. Our forward projection puts the odds of a 10% gain over the next month near 44%. The street (7 analysts) rates it strong buy, with a mean price target of $20. Insiders have been net sellers over the past quarter.
The analysis reads accumulation. Smart money appears to be quietly building positions. This typically precedes a markup phase. Price has moved down 4.9% since our last review. Ethical screening: PASS with passing ethical screen. The risk-adjusted return profile shows modest positive risk-adjusted returns. Our composite framework grades it B. Technically it is momentum reading neutral. Over the past year the shares are up 67%. Our forward projection puts the odds of a 10% gain over the next month near 44%. The street (7 analysts) rates it strong buy, with a mean price target of $20. Insiders have been net sellers over the past quarter.
Our analysis reads accumulation. Smart money appears to be quietly building positions. This typically precedes a markup phase. Price has moved up 4.4% since our last review. Ethical screening: PASS with passing ethical screen. The risk-adjusted return profile shows excellent risk-adjusted returns. Our composite framework grades it B. Technically it is momentum reading neutral. Over the past year the shares are up 67%. Our forward projection puts the odds of a 10% gain over the next month near 44%. The street (7 analysts) rates it strong buy, with a mean price target of $20. Insiders have been net sellers over the past quarter.
Our analysis reads accumulation. Smart money appears to be quietly building positions. This typically precedes a markup phase. Price has moved up 7.0% since our last review. Ethical screening: PASS with passing ethical screen. The risk-adjusted return profile shows excellent risk-adjusted returns. Our composite framework grades it C. Technically it is momentum reading neutral. Over the past year the shares are up 67%. Our forward projection puts the odds of a 10% gain over the next month near 44%. The street (7 analysts) rates it strong buy, with a mean price target of $20. Insiders have been net sellers over the past quarter.
The framework has shifted from markdown to accumulation since the last review. Smart money appears to be quietly building positions. This typically precedes a markup phase. Price has moved up 8.8% since our last review. Ethical screening: PASS with passing ethical screen. The risk-adjusted return profile shows excellent risk-adjusted returns. Our composite framework grades it C. Technically it is momentum reading neutral. Over the past year the shares are up 67%. Our forward projection puts the odds of a 10% gain over the next month near 44%. The street (7 analysts) rates it strong buy, with a mean price target of $20.
Our analysis reads markdown. Price is trending lower. Sellers are in control and the prior trend has reversed. Price has moved up 30.2% since our last review. Ethical screening: PASS with passing ethical screen. The risk-adjusted return profile shows excellent risk-adjusted returns. Our composite framework grades it B. Technically it is momentum reading neutral. Over the past year the shares are up 67%. Our forward projection puts the odds of a 10% gain over the next month near 44%. The street (7 analysts) rates it strong buy, with a mean price target of $20.
Our analysis reads markdown. Price is trending lower. Sellers are in control and the prior trend has reversed. Price has moved down 0.0% since our last review. Ethical screening: PASS with passing ethical screen. The risk-adjusted return profile shows excellent risk-adjusted returns. Our composite framework grades it B. Technically it is momentum reading neutral. Over the past year the shares are up 67%. Our forward projection puts the odds of a 10% gain over the next month near 44%. The street (7 analysts) rates it strong buy, with a mean price target of $20.
Each entry above was written on its date, before the outcome. A journal you can prune is not a journal.
- Should You Be Worried About Tempus AI Stock? Yahoo Finance · 9d ago
- Adaptive Biotechnologies to Report Third Quarter 2026 Financial Results on November 4, 2026 Yahoo Finance · 15d ago
- Could You Have Seen The Run In Tempus AI Stock Coming? Yahoo Finance · 20d ago
- Adaptive Biotechnologies (ADPT) Stock Sees Modest Fair Value Lift On MRD Optimism Yahoo Finance · 21d ago
- Adaptive Biotechnologies (ADPT) Stock Could Be 26% Above Fair Value Despite Guideline Update Yahoo Finance · 25 Sep 2026
Headlines from third-party outlets, linked for reference: not our reporting, not advice.
Screened names in the same industry · explore each on its own page.
| Date | Insider | Title | Type | Shares | Value |
|---|---|---|---|---|---|
| 2026-10-22 | Rubinstein Julie | Pres, COO | S - Sale+OE | 35,643 | $897,457 |
| 2026-10-14 | Rubinstein Julie | Pres, COO | S - Sale+OE | 35,643 | $897,356 |
| 2026-10-09 | Rubinstein Julie | Pres, COO | S - Sale+OE | 35,643 | $919,870 |
| 2026-10-06 | Rubinstein Julie | Pres, COO | S - Sale+OE | 35,643 | $948,223 |
| 2026-10-06 | Bobulsky Susan | Chief Commercial Officer, MRD | S - Sale | 6,444 | $193,320 |
| 2026-09-16 | Lo Francis | Chief People Officer | S - Sale+OE | 115,406 | $3,238,004 |
| 2026-09-15 | Bobulsky Susan | Chief Commercial Officer, MRD | S - Sale | 1,195 | $32,265 |
Public filings, recorded as found. The full tape lives at Insider Intelligence.
| Period | Price then | Price return | Divs per share | $1,000 became | Total return |
|---|---|---|---|---|---|
| 1 month | $13.54 | +29.0% | · | $1,290 | +29.0% |
| 2 months | $12.79 | +36.6% | · | $1,366 | +36.6% |
| 3 months | $12.45 | +40.3% | · | $1,403 | +40.3% |
| 6 months | $15.42 | +13.3% | · | $1,133 | +13.3% |
| 1 year | $10.46 | +67.0% | · | $1,670 | +67.0% |
| 2 years | $3.49 | +400.4% | · | $5,004 | +400.4% |
| 3 years | $7.31 | +138.9% | · | $2,389 | +138.9% |
| 5 years | $38.76 | -54.9% | · | $451 | -54.9% |
Historical returns from market close data. Past performance does not guarantee future results.
This entry now belongs to the ledger. Whatever ADPT does next, these words stay.
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