MAZE
Maze Therapeutics, Inc.
Healthcare · Biotechnology · NGM
$26.05
Close 2026-05-28
✓ ETHICAL PASS

UNKNOWN MOAT
MODERATE
Data Confidence: 71%
Some financial metrics pending
Market Cap
$1.4B
Trailing P/E
Forward P/E
-7.88
Rev Growth
Profit Margin
0.0%
ROE
-38.7%
Analyst Target
$55.00
Recommendation
STRONG BUY
About Maze Therapeutics, Inc.

Maze Therapeutics, Inc., a clinical stage biopharmaceutical company, develops small molecule precision medicines for the treatment of kidney and metabolic diseases in the United States. Its lead programs include MZE829, an oral small molecule inhibitor of apolipoprotein L1, or APOL1, which is in phase II clinical trial for the treatment of patients with APOL1 kidney disease; and MZE782, an oral small molecule inhibitor that is in phase II ready clinical trial for the treatment of phenylketonuria and chronic kidney disease. The company also develops MZE001, an investigational oral small molecule inhibitor of muscle-specific glycogen synthase clinical program for the treatment of Pompe disease. It has a license agreement with Trace Neuroscience, Inc. to discovery research program targets UNC13A; the Shionogi & Co., Ltd to research, develop, manufacture, and commercialize MZE001; and Neurocrine Biosciences, Inc. to discover research program that targets ATXN2. The company was formerly known as Modulus Therapeutics, Inc. and changed its name to Maze Therapeutics, Inc. in September 2018. The company was incorporated in 2017 and is based in South San Francisco, California.

Ethical Screen
Business ActivityPASS
Debt RatioN/A
Cash RatioN/A
Receivables RatioN/A
Revenue Ratio (0.00%)PASS
OverallPASS
Score Ethical: 64.7
Score Valuation: 33.0
Score Quality: 21.2
Score Combined: 32.8

Full Analysis

Opportunity scores, earnings history, insider transactions, institutional holders, analyst consensus, and more.

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Opportunity Scores
Valuation50.0
Quality12.5
Cash Flow0.0
Moat40.0
Balance Sheet0.0
Debt Purity50.0
Liquid Purity50.0
Rev Purity100.0
Compliance100.0
Tier: WATCH · Score: 36.0 · Rank: #4693
Insider Transactions
No insider transaction data.
Top Institutional Holders
No institutional holder data.
Additional Fundamentals
Enterprise Value
$1.2B
Price/Book
3.81
Analysts
11
Total Revenue (TTM)
$20.0M
Total Debt
$61.2M
Rec. Mean
1.08
Short Ratio
5.90
Short % Float
0.1%
Employees
141

Elite Intelligence

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Trade Consideration
The Opportunity
Score 32.8 (P21 — top 78.6% of scored tickers). Unknown Moat. Ethical PASS. 11 analysts at Strong Buy.
Price: $26.05 | Target: $62.55 (+140%)
Score
33
Moat
Unknown
Conviction
Standard
Upside
+140%
The Fundamentals
Profit Margin0.0%
ROE-38.7%
Forward P/E-7.9
Market Cap$1.4B
Position Sizing Scenarios
Stop: $22.14 (-15%) | Entry: $26.05
SharesCostProfit to TargetR:R
To Consensus ($62.55, 11 analysts)
10$260.50+$365.00 (140%)9.3R
50$1,302.50+$1,825.00 (140%)9.3R
100$2,605.00+$3,650.00 (140%)9.3R
Risk Factors
  • Elevated short interest (5.90 days to cover)
The Verdict
Maze Therapeutics, Inc. passes all ethical screens and holds a unknown competitive moat.
Quantitative Grade

A single score combining all analytical layers below. A is strongest, D is weakest.

C
Quant Score
48.0
Risk Grade
Layers
7
Risk Profile

How much could this ticker lose on a bad day? These metrics measure worst-case scenarios from historical data.

VaR 95%
-7.0%
worst expected daily loss, 19 in 20 days
CVaR 95%
-13.3%
avg loss on the worst 5% of days
Annual Volatility
Sortino Ratio
0.53
above 1.0 is good
Max Drawdown
-52.8%
Worst Day
Forward Outlook

Based on 10,000 simulated price paths, here is the probability of where this ticker could be in 30, 60, and 90 days.

30d Prob Up
90d Prob Up
Median Return 30d
Liquidity Score
50
Liquidity Grade
MODERATE
Trend & Momentum

What direction is this ticker actually moving, filtered through noise? Is it speeding up or slowing down?

Kalman Trend
Trend Strength
Momentum Signal
HMM Regime
RSI Signal
Technical Signals

Classic chart signals that institutional traders monitor. Golden Cross is bullish, Death Cross is bearish.

MA Crossover
DEATH_CROSS
Bollinger Position
UPPER_HALF
Beta
Relative Volume
1.6x
Short Interest
Financial Health

Is this company financially sound? The Z-Score measures bankruptcy risk. The F-Score measures fundamental strength.

Altman Z-Score
below 1.81 = distress zone
Piotroski F-Score
Earnings Beat Rate
Earnings Consistency
Correlations

These tickers tend to move together (positive) or in opposite directions (negative). Useful for portfolio diversification.

Most Correlated
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Inverse Correlated
TickerCorrelation
TALABAT.AE-0.216
4150.SR-0.199
8766.T-0.190
4332.SR-0.158
EWG.L-0.155
Seasonality

Does this ticker have consistent patterns on certain days or months? Historical tendencies, not guarantees.

Best Day
Thursday
Worst Day
Friday
Best Month
Sep
Worst Month
Mar
Fri-Mon Effect
-1.2390727003359991
Momentum Rankings

How does this ticker's recent performance compare to the entire universe? Ranked across 1, 3, 6, and 12-month returns.

1M Return
+1.7%
3M Return
-42.4%
6M Return
-28.0%
12M Return
+135.7%
Momentum Rank
#3284
Momentum Signal
FLAT

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