The framework reads markdown. Price is trending lower. Sellers are in control and the prior trend has reversed. Price has moved down 0.0% since our last review. Ethical screening: FAIL. This security does not pass our values-based screening criteria. The risk-adjusted return profile shows modest positive risk-adjusted returns. Our composite framework grades it D. Technically it is sitting below its long-term trend line with momentum reading bearish. Over the past year the shares are down 92%. Our forward projection puts the odds of a 10% gain over the next month near 28%. The street (7 analysts) rates it buy, with a mean price target of $3.
aTyr Pharma, Inc.
ATYR · Nasdaq · USD · Market cap $36M · 58 employees
aTyr Pharma, Inc., a clinical stage biotechnology company, engages in the discovery and development of product candidates that translate tRNA synthetase biology into new therapies for fibrosis and inflammation in the Uni…
FAIL · Does not pass the screenScreen close, 2026-09-21 · not a live quote
Last reviewed 14 days ago
Screened 2026-09-21 · the tape above runs as of 03:09 UTC · two dates, stated on purpose · verdict and workings shown in full · never trimmed
What this means: price 0.37 against the desk's fair-value range, over the last year.
- Trend Markdown
- Insiders no filings inside 60 days, left as found
- Positioning no disclosures inside 60 days, left as found
- Options no verdict drawn today, left as found
- Ethical does not pass the values gate
Our analytic regime reads on this name, dated and marked against the screened price. Small sample per name, and separate from the daily-framework accuracy on the Track Record page.
This name holds its markdown label.
aTyr Pharma, Inc. holds its Markdown at $0.37. Consolidating, no directional conviction, held for 32 days.
| Phase | Markdown · caution |
| Quantitative state | Consolidating, no directional conviction, held for 32 days |
| Price at the screen | $0.37 |
| Valuation | 0.00 trailing · -1.08 forward price to earnings |
| Values screen | FAIL · score 10.0 |
| Beta | 0.66 |
Five Screens, Shown in Full
Does not pass. Cash ratio
| Test | Figure | Limit | What it means | Status |
|---|---|---|---|---|
| Business activity | Permissible | Core business clean | Its core business isn't built on prohibited lines: no gambling, alcohol, tobacco, weapons, or interest-based lending. | Pass |
| Debt load | 28.41% | Below 33% | Interest-bearing debt is just 28.4% of its assets, well under the one-third ceiling: it does not run on borrowed money. | Pass |
| Interest-bearing cash | 185.77% | Below 33% | Interest-bearing cash and securities are 185.8% of assets, above the one-third limit. | Fail |
| Receivables | 0.00% | Below 49% | Money owed to the company is 0.0% of assets, under the 49% limit. | Pass |
| Revenue purity | 0.00% | Below 5% | Only 0.0% of revenue comes from non-compliant sources, under the 5% line. | Pass |
Five checks adapted from AAOIFI screening standards: business activity plus four balance-sheet ratios. All five must pass for ethical clearance. Every figure is arithmetic on public accounts, not judgement.
The Ethical ReadWhy It Falls Short, in Plain English
aTyr Pharma,'s business is fine, but its cash and interest-bearing securities are about 186% of its assets, well over the ~33% line, so it does not pass on the financial screens.
Read as at 2026-10-04. It updates when the underlying figures move, and past reads are kept below.
What the Numbers Say It Is WorthThe Fair Value Range
Our framework reads AVOID
The Street's RangeThird-party analyst targets: 6 covering, consensus Hold. The average target sits +1,229% from the screen price.
Reading the gap · Our more conservative model reads it as fully-to-richly valued here, while the Street is more bullish: a quality-at-a-fair-price name rather than a deep-value one.
Price History & ProjectionsWhere it has been, where the models see it going. History from market close data; projection points are our fair-value estimates and third-party analyst targets, dated to the 2026-09-21 screen.
Fair value and rating are our own model estimates; the Street's range reflects third-party analyst estimates. Analysis, not advice.
The Business, in Plain WordsWhy it gives us pause
At -1.1x forward earnings, the price already runs ahead of the business.
| Forward P/E | -1.1x |
| Trailing P/E | 0.0x |
| EPS, trailing | -0.80 |
| EPS, forward | -0.40 |
| Revenue growth | +0.0%revenue is shrinking |
| Profit margin | 0.0%currently unprofitable |
| Return on equity | -108.1%not currently earning a positive return on equity |
| Debt to equity | 0.18minimal debt: a conservative balance sheet |
| Current ratio | 5.30comfortably covers its short-term bills |
| Beta | 0.66steadier than the market |
| Short interest, float | 0.23% |
| 52-week range | 0.40 - 7.29 |
| Market cap | $36M |
| Employees | 58 |
The risks · The things to watch: it's a small-cap, so the share price can swing harder than the market; as a biotechnology name, trial and regulatory outcomes can move it sharply either way.
Plain-English interpretation of our own screen data. Analysis, not advice.
Where & How to TradeATYR trades on Nasdaq. As a listed security it is accessible through almost any international broker offering its home market. New to this, or investing from abroad? Our guide to accessing global markets covers brokers, currencies and the practical steps.
Every Entry, As Written
The framework has shifted from accumulation to markdown since the last review. Price is trending lower. Sellers are in control and the prior trend has reversed. Price has moved down 21.3% since our last review. Ethical screening: FAIL. This security does not pass our values-based screening criteria. The risk-adjusted return profile shows modest positive risk-adjusted returns. Our composite framework grades it D. Technically it is sitting below its long-term trend line with momentum reading bearish. Over the past year the shares are down 92%. Our forward projection puts the odds of a 10% gain over the next month near 28%. The street (7 analysts) rates it buy, with a mean price target of $3.
The framework has shifted from distribution to accumulation since the last review. Smart money appears to be quietly building positions. This typically precedes a markup phase. Price has moved down 0.0% since our last review. Ethical screening: FAIL. This security does not pass our values-based screening criteria. The risk-adjusted return profile shows modest positive risk-adjusted returns. Our composite framework grades it D. Technically it is sitting below its long-term trend line with momentum reading bearish. Over the past year the shares are down 92%. Our forward projection puts the odds of a 10% gain over the next month near 28%. The street (7 analysts) rates it buy, with a mean price target of $3.
The framework reads distribution. Smart money appears to be selling into strength. Institutional holders may be rotating out. Price has moved down 0.0% since our last review. Ethical screening: FAIL. This security does not pass our values-based screening criteria. The risk-adjusted return profile shows modest positive risk-adjusted returns. Our composite framework grades it D. Technically it is sitting below its long-term trend line with momentum reading bearish. Over the past year the shares are down 92%. Our forward projection puts the odds of a 10% gain over the next month near 28%. The street (7 analysts) rates it buy, with a mean price target of $3.
The framework reads distribution. Smart money appears to be selling into strength. Institutional holders may be rotating out. Price has moved down 0.0% since our last review. Ethical screening: FAIL. This security does not pass our values-based screening criteria. The risk-adjusted return profile shows modest positive risk-adjusted returns. Our composite framework grades it D. Technically it is sitting below its long-term trend line with momentum reading bearish. Over the past year the shares are down 92%. Our forward projection puts the odds of a 10% gain over the next month near 28%. The street (7 analysts) rates it buy, with a mean price target of $3.
The framework reads distribution. Smart money appears to be selling into strength. Institutional holders may be rotating out. Price has moved down 0.0% since our last review. Ethical screening: FAIL. This security does not pass our values-based screening criteria. The risk-adjusted return profile shows modest positive risk-adjusted returns.
The framework reads distribution. Smart money appears to be selling into strength. Institutional holders may be rotating out. Ethical screening: FAIL. This security does not pass our values-based screening criteria. The risk-adjusted return profile shows modest positive risk-adjusted returns.
Each entry above was written on its date, before the outcome. A journal you can prune is not a journal.
| Date | Insider | Title | Type | Shares | Value |
|---|---|---|---|---|---|
| 2026-02-04 | BROADFOOT JILL MARIE | Chief Financial Officer | 1,558 | $1,521 | |
| 2026-02-04 | SHUKLA SANJAY S | Chief Executive Officer | 3,745 | $3,655 | |
| 2026-02-04 | DENYES NANCY | General Counsel | 1,118 | $1,091 | |
| 2026-02-03 | BROADFOOT JILL MARIE | Chief Financial Officer | 3,750 | · | |
| 2026-02-03 | SHUKLA SANJAY S | Chief Executive Officer | 10,375 | · | |
| 2026-02-03 | DENYES NANCY | General Counsel | 2,687 | · | |
| 2025-10-09 | SCHIMMEL PAUL R | Director | 1,000,000 | $911,801 | |
| 2025-03-17 | GROSS JANE A | Director | 3,750 | $15,000 | |
| 2025-02-04 | BROADFOOT JILL MARIE | Chief Financial Officer | 1,254 | $4,740 | |
| 2025-02-04 | DENYES NANCY | General Counsel | 899 | $3,398 |
Public filings, recorded as found. The full tape lives at Insider Intelligence.
| Period | Price then | Price return | Divs per share | $1,000 became | Total return |
|---|---|---|---|---|---|
| 1 month | $0.95 | -51.5% | · | $486 | -51.5% |
| 2 months | $0.83 | -44.6% | · | $554 | -44.6% |
| 3 months | $0.87 | -46.9% | · | $531 | -46.9% |
| 6 months | $0.76 | -39.7% | · | $603 | -39.7% |
| 1 year | $5.50 | -91.6% | · | $84 | -91.6% |
| 2 years | $1.93 | -76.1% | · | $239 | -76.1% |
| 3 years | $2.20 | -79.0% | · | $210 | -79.0% |
| 5 years | $4.75 | -90.3% | · | $97 | -90.3% |
Historical returns from market close data. Past performance does not guarantee future results.
This entry now belongs to the ledger. Whatever ATYR does next, these words stay.
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Join the deskScreening is research, not a fatwa and not financial advice. Figures are drawn from public accounts at the screen date shown. Always manage your risk.