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The Screen · Healthcare · Biotechnology

aTyr Pharma, Inc.

ATYR · Nasdaq · USD · Market cap $36M · 58 employees

aTyr Pharma, Inc., a clinical stage biotechnology company, engages in the discovery and development of product candidates that translate tRNA synthetase biology into new therapies for fibrosis and inflammation in the Uni…

FAIL · Does not pass the screen
0.37 USD

Screen close, 2026-09-21 · not a live quote
Last reviewed 14 days ago

Screened 2026-09-21 · the tape above runs as of 03:09 UTC · two dates, stated on purpose · verdict and workings shown in full · never trimmed

PRICE · FAIR-VALUE RANGE1M3M6MYTD1Y3Y5Y

What this means: price 0.37 against the desk's fair-value range, over the last year.

Current read
Markdown ?
AVOID · screened 2026-09-21
  • Trend Markdown
  • Insiders no filings inside 60 days, left as found
  • Positioning no disclosures inside 60 days, left as found
  • Options no verdict drawn today, left as found
  • Ethical does not pass the values gate
Price0.37 USD
Ethical score10.0/100
RatingAVOID
Our investment reviews on this name
2026-09-24Read Markdown0.37+0.0% to today
2026-08-22Read Accumulation0.47-21.3% to today
2026-07-02Read Distribution0.47-21.3% to today ✓

Our analytic regime reads on this name, dated and marked against the screened price. Small sample per name, and separate from the daily-framework accuracy on the Track Record page.

The full research record, in depth, below
The Label · The Season, Not the Day

This name holds its markdown label.

aTyr Pharma, Inc. holds its Markdown at $0.37. Consolidating, no directional conviction, held for 32 days.

As held on the ledger · 2026-09-21
PhaseMarkdown · caution
Quantitative stateConsolidating, no directional conviction, held for 32 days
Price at the screen$0.37
Valuation0.00 trailing · -1.08 forward price to earnings
Values screenFAIL · score 10.0
Beta0.66
The Workings

Five Screens, Shown in Full

Does not pass. Cash ratio

TestFigureLimitWhat it meansStatus
Business activity Permissible Core business clean Its core business isn't built on prohibited lines: no gambling, alcohol, tobacco, weapons, or interest-based lending. Pass
Debt load 28.41% Below 33% Interest-bearing debt is just 28.4% of its assets, well under the one-third ceiling: it does not run on borrowed money. Pass
Interest-bearing cash 185.77% Below 33% Interest-bearing cash and securities are 185.8% of assets, above the one-third limit. Fail
Receivables 0.00% Below 49% Money owed to the company is 0.0% of assets, under the 49% limit. Pass
Revenue purity 0.00% Below 5% Only 0.0% of revenue comes from non-compliant sources, under the 5% line. Pass

Five checks adapted from AAOIFI screening standards: business activity plus four balance-sheet ratios. All five must pass for ethical clearance. Every figure is arithmetic on public accounts, not judgement.

The Ethical Read

Why It Falls Short, in Plain English

aTyr Pharma,'s business is fine, but its cash and interest-bearing securities are about 186% of its assets, well over the ~33% line, so it does not pass on the financial screens.

Read as at 2026-10-04. It updates when the underlying figures move, and past reads are kept below.

What the Numbers Say It Is Worth

The Fair Value Range

Our framework reads AVOID

The Street's Range
1.00Street low 4.92Street average 20.00Street high 0.37Price

Third-party analyst targets: 6 covering, consensus Hold. The average target sits +1,229% from the screen price.

Reading the gap · Our more conservative model reads it as fully-to-richly valued here, while the Street is more bullish: a quality-at-a-fair-price name rather than a deep-value one.

Price History & Projections
$21.6$10.2$-1.1TODAY5y agoPROJECTIONStreet high$20.00 +4237%Street avg$4.92 +966%

Where it has been, where the models see it going. History from market close data; projection points are our fair-value estimates and third-party analyst targets, dated to the 2026-09-21 screen.

Fair value and rating are our own model estimates; the Street's range reflects third-party analyst estimates. Analysis, not advice.

The Business, in Plain Words

Why it gives us pause

At -1.1x forward earnings, the price already runs ahead of the business.

The fundamentals · plain-English read
Forward P/E-1.1x
Trailing P/E0.0x
EPS, trailing-0.80
EPS, forward-0.40
Revenue growth+0.0%revenue is shrinking
Profit margin0.0%currently unprofitable
Return on equity-108.1%not currently earning a positive return on equity
Debt to equity0.18minimal debt: a conservative balance sheet
Current ratio5.30comfortably covers its short-term bills
Beta0.66steadier than the market
Short interest, float0.23%
52-week range0.40 - 7.29
Market cap$36M
Employees58

The risks · The things to watch: it's a small-cap, so the share price can swing harder than the market; as a biotechnology name, trial and regulatory outcomes can move it sharply either way.

Plain-English interpretation of our own screen data. Analysis, not advice.

Where & How to Trade

ATYR trades on Nasdaq. As a listed security it is accessible through almost any international broker offering its home market. New to this, or investing from abroad? Our guide to accessing global markets covers brokers, currencies and the practical steps.

The Dated Journal · Newest First, Never Edited

Every Entry, As Written

2026-10-02 Markdown $0.37 +0.0% Entry 7

The framework reads markdown. Price is trending lower. Sellers are in control and the prior trend has reversed. Price has moved down 0.0% since our last review. Ethical screening: FAIL. This security does not pass our values-based screening criteria. The risk-adjusted return profile shows modest positive risk-adjusted returns. Our composite framework grades it D. Technically it is sitting below its long-term trend line with momentum reading bearish. Over the past year the shares are down 92%. Our forward projection puts the odds of a 10% gain over the next month near 28%. The street (7 analysts) rates it buy, with a mean price target of $3.

2026-09-24 Markdown · changed $0.37 -21.3% Entry 6

The framework has shifted from accumulation to markdown since the last review. Price is trending lower. Sellers are in control and the prior trend has reversed. Price has moved down 21.3% since our last review. Ethical screening: FAIL. This security does not pass our values-based screening criteria. The risk-adjusted return profile shows modest positive risk-adjusted returns. Our composite framework grades it D. Technically it is sitting below its long-term trend line with momentum reading bearish. Over the past year the shares are down 92%. Our forward projection puts the odds of a 10% gain over the next month near 28%. The street (7 analysts) rates it buy, with a mean price target of $3.

2026-08-22 Accumulation · changed $0.47 +0.0% Entry 5

The framework has shifted from distribution to accumulation since the last review. Smart money appears to be quietly building positions. This typically precedes a markup phase. Price has moved down 0.0% since our last review. Ethical screening: FAIL. This security does not pass our values-based screening criteria. The risk-adjusted return profile shows modest positive risk-adjusted returns. Our composite framework grades it D. Technically it is sitting below its long-term trend line with momentum reading bearish. Over the past year the shares are down 92%. Our forward projection puts the odds of a 10% gain over the next month near 28%. The street (7 analysts) rates it buy, with a mean price target of $3.

2026-07-22 Distribution $0.47 +0.0% Entry 4

The framework reads distribution. Smart money appears to be selling into strength. Institutional holders may be rotating out. Price has moved down 0.0% since our last review. Ethical screening: FAIL. This security does not pass our values-based screening criteria. The risk-adjusted return profile shows modest positive risk-adjusted returns. Our composite framework grades it D. Technically it is sitting below its long-term trend line with momentum reading bearish. Over the past year the shares are down 92%. Our forward projection puts the odds of a 10% gain over the next month near 28%. The street (7 analysts) rates it buy, with a mean price target of $3.

2026-07-18 Distribution $0.47 +0.0% Entry 3

The framework reads distribution. Smart money appears to be selling into strength. Institutional holders may be rotating out. Price has moved down 0.0% since our last review. Ethical screening: FAIL. This security does not pass our values-based screening criteria. The risk-adjusted return profile shows modest positive risk-adjusted returns. Our composite framework grades it D. Technically it is sitting below its long-term trend line with momentum reading bearish. Over the past year the shares are down 92%. Our forward projection puts the odds of a 10% gain over the next month near 28%. The street (7 analysts) rates it buy, with a mean price target of $3.

2026-07-03 Distribution $0.47 +0.0% Entry 2

The framework reads distribution. Smart money appears to be selling into strength. Institutional holders may be rotating out. Price has moved down 0.0% since our last review. Ethical screening: FAIL. This security does not pass our values-based screening criteria. The risk-adjusted return profile shows modest positive risk-adjusted returns.

2026-07-02 Distribution $0.47 Entry 1

The framework reads distribution. Smart money appears to be selling into strength. Institutional holders may be rotating out. Ethical screening: FAIL. This security does not pass our values-based screening criteria. The risk-adjusted return profile shows modest positive risk-adjusted returns.

Each entry above was written on its date, before the outcome. A journal you can prune is not a journal.

The Insider Ledger · Form 4 Filings, As Filed
Most recent filings · ATYR
DateInsiderTitleTypeSharesValue
2026-02-04 BROADFOOT JILL MARIE Chief Financial Officer 1,558 $1,521
2026-02-04 SHUKLA SANJAY S Chief Executive Officer 3,745 $3,655
2026-02-04 DENYES NANCY General Counsel 1,118 $1,091
2026-02-03 BROADFOOT JILL MARIE Chief Financial Officer 3,750 ·
2026-02-03 SHUKLA SANJAY S Chief Executive Officer 10,375 ·
2026-02-03 DENYES NANCY General Counsel 2,687 ·
2025-10-09 SCHIMMEL PAUL R Director 1,000,000 $911,801
2025-03-17 GROSS JANE A Director 3,750 $15,000
2025-02-04 BROADFOOT JILL MARIE Chief Financial Officer 1,254 $4,740
2025-02-04 DENYES NANCY General Counsel 899 $3,398

Public filings, recorded as found. The full tape lives at Insider Intelligence.

What Holding Actually Paid · Price Plus Dividends
If $1,000 had been placed · historical, not a promise
PeriodPrice thenPrice returnDivs per share$1,000 becameTotal return
1 month $0.95 -51.5% · $486 -51.5%
2 months $0.83 -44.6% · $554 -44.6%
3 months $0.87 -46.9% · $531 -46.9%
6 months $0.76 -39.7% · $603 -39.7%
1 year $5.50 -91.6% · $84 -91.6%
2 years $1.93 -76.1% · $239 -76.1%
3 years $2.20 -79.0% · $210 -79.0%
5 years $4.75 -90.3% · $97 -90.3%

Historical returns from market close data. Past performance does not guarantee future results.

The Ledger's Promise

This entry now belongs to the ledger. Whatever ATYR does next, these words stay.

aTyr Pharma, Inc. · ATYR · Markdown · $0.37
Recorded 2026-09-21 · before the outcome · scored mechanically

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