The analysis reads markdown. Price is trending lower. Sellers are in control and the prior trend has reversed. Price has moved up 3.0% since our last review. Ethical screening: FAIL. This security does not pass our values-based screening criteria. The risk-adjusted return profile shows good risk-adjusted returns. Our composite framework grades it C. Technically it is holding around 18% above its long-term trend line with momentum reading oversold. Over the past year the shares are up 165%. Our forward projection puts the odds of a 10% gain over the next month near 35%. The street (11 analysts) rates it none, with a mean price target of $69.
MBX Biosciences, Inc.
MBX · Nasdaq · USD · Market cap $2.4B · 63 employees
MBX Biosciences, Inc., a clinical-stage biopharmaceutical company, focuses on the discovery and development of precision peptide therapies for the treatment of endocrine and metabolic disorders.
FAIL · Does not pass the screenPrice as of 23 Oct 2026Daily close, not a live quoteLast reviewed 6 days ago
Screened 2026-10-23 · the tape above runs as of 02:01 UTC · two dates, stated on purpose · verdict and workings shown in full · never trimmed
Key facts today
- Price48.50 USD at the 23 Oct 2026 close
- Ethical screenDoes not pass
- OptionsOpen interest leans to puts (put/call 1.07)
- Last reviewed23 Oct 2026 (6 days ago)
A summary of the dated readings below, not a live quote and not advice.
What this means: price 48.50 against the desk's fair-value range, base estimate 88.00, over the last year.
- Trend Markdown
- Insiders no filings inside 60 days, left as found
- Positioning no disclosures inside 60 days, left as found
- Options put/call open interest 1.07, read 2026-10-24
- Ethical does not pass the values gate
Our analytic regime reads on this name, dated and marked against the screened price. Small sample per name, and separate from the daily-framework accuracy on the Track Record page.
This name holds its markdown label.
MBX Biosciences, Inc. holds its Markdown at $48.50. Consolidating, no directional conviction, held for 48 days.
| Phase | Markdown · caution |
| Quantitative state | Consolidating, no directional conviction, held for 48 days |
| Price at the screen | $48.50 |
| Valuation | N/A trailing · -12.69 forward price to earnings |
| Values screen | FAIL · score 70.0 |
| Beta | 0.10 |
Five Screens, Shown in Full
Does not pass. Interest-bearing securities
| Test | Figure | Limit | What it means | Status |
|---|---|---|---|---|
| Business activity | Permissible | Core business clean | Its core business isn't built on prohibited lines: no gambling, alcohol, tobacco, weapons, or interest-based lending. | Pass |
| Debt load | 0.15% | Below 33% | Interest-bearing debt is just 0.2% of its assets, well under the one-third ceiling: it does not run on borrowed money. | Pass |
| Interest-bearing cash | 77.48% | Below 33% | Interest-bearing cash and securities are 77.5% of assets, above the one-third limit. | Fail |
| Receivables | 20.10% | Below 49% | Money owed to the company is 20.1% of assets, under the 49% limit. | Pass |
Five checks adapted from AAOIFI screening standards: business activity plus four balance-sheet ratios. All five must pass for ethical clearance. Every figure is arithmetic on public accounts, not judgement.
The Ethical ReadWhy It Falls Short, in Plain English
MBX Biosciences,'s business is fine, but its cash and interest-bearing securities are about 77% of its assets, well over the ~33% line, so it does not pass on the financial screens.
Read as at 2026-10-28. It updates when the underlying figures move, and past reads are kept below.
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The Fair Value Range
Fair value range in USD, drawn from the 2026-10-23 screen. The gold marker is the market price at the same screen. A 81.4% margin of safety to the base estimate.
Third-party analyst targets: 10 covering, consensus Strong Buy. The average target sits +81% from the screen price.
Reading the gap · Both our model and the analysts see meaningful upside from here.
Price History & ProjectionsWhere it has been, where the models see it going. History from market close data; projection points are our fair-value estimates and third-party analyst targets, dated to the 2026-10-23 screen.
Fair value and rating are our own model estimates; the Street's range reflects third-party analyst estimates. Analysis, not advice.
The Business, in Plain WordsClinical stage biotech with zero profits
A clinical stage biotech is a bit like backing an untested athlete to win the Olympics, you pay upfront for potential that may never arrive. MBX Biosciences focuses on peptide therapies for endocrine disorders, with its lead candidate still in trials and no approved products. The numbers show a forward P/E of negative 16 times, zero profit margin and return on equity at negative 26 percent, which is why the opportunity rating stays at none.
Analysts give a strong buy call with a 70 dollar median target against the current 62.92 price, yet the ethical screen returns insufficient data because basic financial ratios are missing. That gap alone blocks any positive view here.
High clinical failure rates remain the core risk for any early stage drug maker, and the lack of moat or ethical clarity adds further uncertainty around long term viability. Analysis, not advice.
| Forward P/E | -12.7x |
| EPS, trailing | -2.37 |
| EPS, forward | -3.98 |
| Profit margin | 0.0%currently unprofitable |
| Return on equity | -33.2%not currently earning a positive return on equity |
| FCF yield | -2.18% |
| Debt to equity | 0.82moderate, manageable leverage |
| Current ratio | 18.08comfortably covers its short-term bills |
| Beta | 0.10barely tracks the market's swings |
| Short interest, float | 0.13% |
| 52-week range | 14.61 - 72.64 |
| Market cap | $2.4B |
| Employees | 63 |
The risks · The things to watch: as a biotechnology name, trial and regulatory outcomes can move it sharply either way.
Plain-English interpretation of our own screen data. Analysis, not advice.
Where & How to TradeMBX trades on Nasdaq. As a listed security it is accessible through almost any international broker offering its home market. New to this, or investing from abroad? Our guide to accessing global markets covers brokers, currencies and the practical steps.
Every Entry, As Written
The analysis reads markdown. Price is trending lower. Sellers are in control and the prior trend has reversed. Price has moved down 19.6% since our last review. Ethical screening: FAIL. This security does not pass our values-based screening criteria. The risk-adjusted return profile shows good risk-adjusted returns. Our composite framework grades it C. Technically it is holding around 18% above its long-term trend line with momentum reading neutral. Over the past year the shares are up 165%. Our forward projection puts the odds of a 10% gain over the next month near 35%. The street (11 analysts) rates it none, with a mean price target of $69.
Our analysis reads markdown. Price is trending lower. Sellers are in control and the prior trend has reversed. Price has moved down 8.2% since our last review. Ethical screening: FAIL. This security does not pass our values-based screening criteria. The risk-adjusted return profile shows good risk-adjusted returns. Our composite framework grades it C. Technically it is holding around 18% above its long-term trend line with momentum reading neutral. Over the past year the shares are up 165%. Our forward projection puts the odds of a 10% gain over the next month near 35%. The street (11 analysts) rates it none, with a mean price target of $69.
The framework has shifted from markup to markdown since the last review. Price is trending lower. Sellers are in control and the prior trend has reversed. Price has moved up 5.5% since our last review. Ethical screening: FAIL. This security does not pass our values-based screening criteria. The risk-adjusted return profile shows good risk-adjusted returns. Our composite framework grades it C. Technically it is holding around 18% above its long-term trend line with momentum reading neutral. Over the past year the shares are up 165%. Our forward projection puts the odds of a 10% gain over the next month near 35%. The street (11 analysts) rates it none, with a mean price target of $69.
Our analysis reads markup. Price is trending higher with momentum. The crowd has caught on and buyers are in control. Price has moved up 77.2% since our last review. Ethical screening: FAIL. This security does not pass our values-based screening criteria. The risk-adjusted return profile shows excellent risk-adjusted returns. Our composite framework grades it C. Technically it is holding around 18% above its long-term trend line with momentum reading neutral. Over the past year the shares are up 165%. Our forward projection puts the odds of a 10% gain over the next month near 35%. The street (11 analysts) rates it none, with a mean price target of $69.
Our analysis reads markup. Price is trending higher with momentum. The crowd has caught on and buyers are in control. Price has moved down 0.0% since our last review. Ethical screening: FAIL. This security does not pass our values-based screening criteria. The risk-adjusted return profile shows good risk-adjusted returns. Our composite framework grades it C. Technically it is holding around 18% above its long-term trend line with momentum reading neutral. Over the past year the shares are up 165%. Our forward projection puts the odds of a 10% gain over the next month near 35%. The street (11 analysts) rates it none, with a mean price target of $69.
Our analysis reads markup. Price is trending higher with momentum. The crowd has caught on and buyers are in control. Price has moved down 0.0% since our last review. Ethical screening: FAIL. This security does not pass our values-based screening criteria. The risk-adjusted return profile shows good risk-adjusted returns.
Our analysis reads markup. Price is trending higher with momentum. The crowd has caught on and buyers are in control. Ethical screening: FAIL. This security does not pass our values-based screening criteria. The risk-adjusted return profile shows good risk-adjusted returns.
Each entry above was written on its date, before the outcome. A journal you can prune is not a journal.
- MBX Biosciences to Participate in Upcoming November Investor Conferences Yahoo Finance · 16d ago
- Is MBX Biosciences (MBX) Still Undervalued After Its Pullback From A Strong 1 Year Run? Yahoo Finance · 19d ago
- MBX Biosciences (MBX) Stock Could Be Above Fair Value As Shares Jumped 257% Yahoo Finance · 19d ago
- MBX Biosciences to Participate in Upcoming Investor Conferences Yahoo Finance · 9 Sep 2026
- MBX Biosciences Announces Appointment of Jeff Held as Chief Legal Officer Yahoo Finance · 8 Sep 2026
Headlines from third-party outlets, linked for reference: not our reporting, not advice.
Screened names in the same industry · explore each on its own page.
| Period | Price then | Price return | Divs per share | $1,000 became | Total return |
|---|---|---|---|---|---|
| 1 month | $40.08 | -24.2% | · | $758 | -24.2% |
| 2 months | $31.00 | -2.1% | · | $980 | -2.1% |
| 3 months | $27.95 | +8.6% | · | $1,086 | +8.6% |
| 6 months | $28.43 | +6.8% | · | $1,068 | +6.8% |
| 1 year | $11.45 | +165.1% | · | $2,651 | +165.1% |
Historical returns from market close data. Past performance does not guarantee future results.
This entry now belongs to the ledger. Whatever MBX does next, these words stay.
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