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The Screen · Healthcare

Centessa Pharmaceuticals plc logoCentessa Pharmaceuticals plc

CNTA · Nasdaq · USD · Market cap $6.3B

PASS · Titan Ethical
40.50 USD

Screen close, 2026-08-24 · not a live quote
Last reviewed 44 days ago

Screened 2026-08-24 · the tape above runs as of 01:04 UTC · two dates, stated on purpose · verdict and workings shown in full · never trimmed

PRICE · FAIR-VALUE RANGE1M3M6MYTD1Y3Y5Y
38.0039.0045.00

What this means: price 40.50 against the desk's fair-value range, base estimate 39.00, over the last year.

Current read
Accumulation ?
AVOID · screened 2026-08-24
  • Trend Accumulation
  • Insiders no filings inside 60 days, left as found
  • Positioning no disclosures inside 60 days, left as found
  • Options no verdict drawn today, left as found
  • Ethical passes the values gate
Price40.50 USD
Fair value39.00
RatingAVOID
Our investment reviews on this name
2026-07-02Read Accumulation39.62+2.2% to today ✓

Our analytic regime reads on this name, dated and marked against the screened price. Small sample per name, and separate from the daily-framework accuracy on the Track Record page.

The full research record, in depth, below
The Label · The Season, Not the Day

This name holds its accumulation label.

Centessa Pharmaceuticals plc holds its Accumulation at $40.50. Elevated stress, defensive posture warranted, held for 38 days.

As held on the ledger · 2026-08-24
PhaseAccumulation
Quantitative stateElevated stress, defensive posture warranted, held for 38 days
Price at the screen$40.50
ValuationN/A trailing · -22.75 forward price to earnings
Values screenPASS
Beta1.12
The Workings

Five Screens, Shown in Full

Full pass across all five screens. This security clears the Titan Ethical Standard: its business and its balance sheet both stay inside the lines.

TestFigureLimitWhat it meansStatus
Business activity Permissible Core business clean Its core business isn't built on prohibited lines: no gambling, alcohol, tobacco, weapons, or interest-based lending. Pass
Debt load 1.93% Below 33% Interest-bearing debt is just 1.9% of its assets, well under the one-third ceiling: it does not run on borrowed money. Pass
Interest-bearing cash 4.51% Below 33% Cash held in interest-bearing accounts and securities is 4.5% of assets, under the one-third limit. Pass
Receivables 0.00% Below 49% Money owed to the company is 0.0% of assets, under the 49% limit. Pass
Revenue purity 0.00% Below 5% Only 0.0% of revenue comes from non-compliant sources, under the 5% line. Pass

Five checks adapted from AAOIFI screening standards: business activity plus four balance-sheet ratios. All five must pass for ethical clearance. Every figure is arithmetic on public accounts, not judgement.

The Ethical Read

Why It Clears, in Plain English

Centessa Pharmaceuticals clears all five screens. Its business is in a permissible area, its debt is near-nil, and almost none of its income is interest, so it passes.

Read as at 2026-10-04. It updates when the underlying figures move, and past reads are kept below.

What the Numbers Say It Is Worth

The Fair Value Range

Our framework reads AVOID: it trades above our $39.00 fair value estimate.

38.00Conservative39.00Base case45.00Growth case 40.50Price

Fair value range in USD, drawn from the 2026-08-24 screen. The gold marker is the market price at the same screen. The price runs 3.7% above the base estimate.

The Street's Range
38.00Street low 39.00Street average 45.00Street high 40.50Price

Third-party analyst targets: 4 covering, consensus Hold. The average target sits −4% from the screen price.

Reading the gap · Both our model and the Street see limited upside at this price.

Price History & Projections
$48.2$24.8$1.4TODAY5y agoPROJECTIONStreet high$45.00 +13%Street avg$39.00 -2%Our fair value$39.00 -2%Conservative$38.00 -4%

Where it has been, where the models see it going. History from market close data; projection points are our fair-value estimates and third-party analyst targets, dated to the 2026-08-24 screen.

Fair value and rating are our own model estimates; the Street's range reflects third-party analyst estimates. Analysis, not advice.

The Business, in Plain Words

Biotech dreams priced above fair value rarely deliver

Picture a lab racing to turn one promising molecule into a medicine that actually reaches patients. The clock ticks, cash burns, and regulators demand proof. Centessa sits in exactly that spot, with its shares changing hands at $40.50 against our fair value of $39.00.

We pass because the numbers give no margin. Forward earnings sit at a negative 22.8 times, profit margins remain at zero, and return on equity runs at minus 57 percent. Four analysts call it a hold with a median target of $39, yet the market already prices the story as if success is assured.

That leaves real downside if trials slip or dilution follows. The ethical screen clears, yet the valuation and cash losses still fail our basic test for owning the business today. Analysis, not advice.

The fundamentals · plain-English read
Forward P/E-22.8x
EPS, trailing-1.78
EPS, forward-1.78
Profit margin0.0%currently unprofitable
Return on equity-57.4%not currently earning a positive return on equity
FCF yield-2.05%
Debt to equity0.24minimal debt: a conservative balance sheet
Current ratio9.53comfortably covers its short-term bills
Beta1.12moves a little more than the market
Short interest, float0.01%
52-week range13.22 - 40.56
Market cap$6.3B

The risks · The main risks here are ordinary market swings and the chance our fair-value read proves too optimistic.

Plain-English interpretation of our own screen data. Analysis, not advice.

Where & How to Trade

CNTA trades on Nasdaq. As a listed security it is accessible through almost any international broker offering its home market. New to this, or investing from abroad? Our guide to accessing global markets covers brokers, currencies and the practical steps.

The Dated Journal · Newest First, Never Edited

Every Entry, As Written

2026-10-02 Accumulation $40.50 +0.0% Entry 6

The framework reads accumulation. Smart money appears to be quietly building positions. This typically precedes a markup phase. Price has moved down 0.0% since our last review. Ethical screening: PASS with ethical screening pending. The risk-adjusted return profile shows excellent risk-adjusted returns. Our composite framework grades it B. Technically it is holding around 47% above its long-term trend line with momentum reading bullish. Over the past year the shares are up 227%. Our forward projection puts the odds of a 10% gain over the next month near 46%. The street (7 analysts) rates it none, with a mean price target of $45.

2026-08-25 Accumulation $40.50 +0.0% Entry 5

The framework reads accumulation. Smart money appears to be quietly building positions. This typically precedes a markup phase. Price has moved down 0.0% since our last review. Ethical screening: PASS with ethical screening pending. The risk-adjusted return profile shows excellent risk-adjusted returns. Our composite framework grades it B. Technically it is holding around 47% above its long-term trend line with momentum reading bullish. Over the past year the shares are up 227%. Our forward projection puts the odds of a 10% gain over the next month near 46%. The street (7 analysts) rates it none, with a mean price target of $45.

2026-07-25 Accumulation $40.50 +2.2% Entry 4

The framework reads accumulation. Smart money appears to be quietly building positions. This typically precedes a markup phase. Price has moved up 2.2% since our last review. Ethical screening: PASS with ethical screening pending. The risk-adjusted return profile shows excellent risk-adjusted returns. Our composite framework grades it B. Technically it is holding around 47% above its long-term trend line with momentum reading bullish. Over the past year the shares are up 227%. Our forward projection puts the odds of a 10% gain over the next month near 46%. The street (7 analysts) rates it none, with a mean price target of $45.

2026-07-18 Accumulation $39.62 +0.0% Entry 3

The framework reads accumulation. Smart money appears to be quietly building positions. This typically precedes a markup phase. Price has moved down 0.0% since our last review. Ethical screening: PASS with ethical screening pending. The risk-adjusted return profile shows excellent risk-adjusted returns. Our composite framework grades it B. Technically it is holding around 47% above its long-term trend line with momentum reading bullish. Over the past year the shares are up 227%. Our forward projection puts the odds of a 10% gain over the next month near 46%. The street (7 analysts) rates it none, with a mean price target of $45.

2026-07-03 Accumulation $39.62 +0.0% Entry 2

The framework reads accumulation. Smart money appears to be quietly building positions. This typically precedes a markup phase. Price has moved down 0.0% since our last review. Ethical screening: PASS with ethical screening pending. The risk-adjusted return profile shows excellent risk-adjusted returns.

2026-07-02 Accumulation $39.62 Entry 1

The framework reads accumulation. Smart money appears to be quietly building positions. This typically precedes a markup phase. Ethical screening: PASS with ethical screening pending. The risk-adjusted return profile shows excellent risk-adjusted returns.

Each entry above was written on its date, before the outcome. A journal you can prune is not a journal.

Latest News · What the Market Is Reading on CNTA

Headlines from third-party outlets, linked for reference: not our reporting, not advice.

Related Securities · Others in CNTA's Space

Screened names in the same industry · explore each on its own page.

The Insider Ledger · Form 4 Filings, As Filed
Most recent filings · CNTA
DateInsiderTitleTypeSharesValue
2026-03-26 ANDERSON KAREN M Officer 41,076 $329,019
2026-03-26 WEINHOFF GREGORY M Officer 23,998 $92,392
2026-03-26 WEINHOFF GREGORY M Officer 23,998 $719,940
2026-03-26 ANDERSON KAREN M Officer 41,076 $1,237,382
2026-03-17 ANDERSON KAREN M Officer 74,811 $299,992
2026-03-17 ANDERSON KAREN M Officer 74,811 $2,109,180
2026-03-13 ANDERSON KAREN M Officer 109,398 $438,686
2026-03-13 ANDERSON KAREN M Officer 109,398 $436,258
2026-03-13 WEINHOFF GREGORY M Officer 73,196 $1,927,131
2026-03-13 ANDERSON KAREN M Officer 120,029 $3,150,673

Public filings, recorded as found. The full tape lives at Insider Intelligence.

The Political Ledger · Congressional Disclosures
Disclosures naming CNTA
DatePoliticianPartyTypeAmount
2026-05-01 Ro Khanna Democrat sell 15K–50K
What Holding Actually Paid · Price Plus Dividends
If $1,000 had been placed · historical, not a promise
PeriodPrice thenPrice returnDivs per share$1,000 becameTotal return
1 month $39.59 +0.2% · $1,002 +0.2%
2 months $39.48 +0.4% · $1,004 +0.4%
3 months $27.22 +45.7% · $1,457 +45.7%
6 months $27.18 +45.9% · $1,459 +45.9%
1 year $12.12 +227.2% · $3,272 +227.2%
2 years $9.08 +336.7% · $4,367 +336.7%
3 years $4.61 +760.1% · $8,601 +760.1%
5 years $21.71 +82.6% · $1,826 +82.6%

Historical returns from market close data. Past performance does not guarantee future results.

The Ledger's Promise

This entry now belongs to the ledger. Whatever CNTA does next, these words stay.

Centessa Pharmaceuticals plc · CNTA · Accumulation · $40.50
Recorded 2026-08-24 · before the outcome · scored mechanically

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