The analysis reads markdown. Price is trending lower. Sellers are in control and the prior trend has reversed. Price has moved down 0.0% since our last review. Ethical screening: FAIL. This security does not pass our values-based screening criteria. The risk-adjusted return profile shows good risk-adjusted returns. Our composite framework grades it D. Technically it is holding around 6% above its long-term trend line with momentum reading bearish. Over the past year the shares are up 169%. Our forward projection puts the odds of a 10% gain over the next month near 34%. The street (5 analysts) rates it none, with a mean price target of $4.
Lexicon Pharmaceuticals, Inc.
LXRX · Nasdaq · USD · Market cap $906M · 81 employees
Lexicon Pharmaceuticals, Inc., a biopharmaceutical company, focuses on the discovery, development, and commercialization of pharmaceutical products for the treatment of human disease.
FAIL · Does not pass the screenPrice as of 23 Oct 2026Daily close, not a live quoteLast reviewed 6 days ago
Screened 2026-10-23 · the tape above runs as of 10:09 UTC · two dates, stated on purpose · verdict and workings shown in full · never trimmed
Key facts today
- Price1.42 USD at the 23 Oct 2026 close
- Ethical screenDoes not pass
- OptionsOpen interest leans slightly to calls (put/call 0.89)
- Last reviewed23 Oct 2026 (6 days ago)
A summary of the dated readings below, not a live quote and not advice.
What this means: price 1.42 against the desk's fair-value range, base estimate 2.84, over the last year.
- Trend Markdown
- Insiders no filings inside 60 days, left as found
- Positioning no disclosures inside 60 days, left as found
- Options put/call open interest 0.89, read 2026-10-27
- Ethical does not pass the values gate
Our analytic regime reads on this name, dated and marked against the screened price. Small sample per name, and separate from the daily-framework accuracy on the Track Record page.
This name holds its markdown label.
Lexicon Pharmaceuticals, Inc. holds its Markdown at $1.42. Consolidating, no directional conviction, held for 64 days.
| Phase | Markdown · caution |
| Quantitative state | Consolidating, no directional conviction, held for 64 days |
| Price at the screen | $1.42 |
| Valuation | N/A trailing · -11.49 forward price to earnings |
| Values screen | FAIL · score 70.0 |
| Beta | 1.04 |
Five Screens, Shown in Full
Does not pass. Debt ratio
| Test | Figure | Limit | What it means | Status |
|---|---|---|---|---|
| Business activity | Permissible | Core business clean | Its core business isn't built on prohibited lines: no gambling, alcohol, tobacco, weapons, or interest-based lending. | Pass |
| Debt load | 33.96% | Below 33% | Interest-bearing debt is 34.0% of its assets, above the one-third ceiling the screen allows. | Fail |
| Interest-bearing cash | 33.46% | Below 33% | Interest-bearing cash and securities are 33.5% of assets, above the one-third limit. | Fail |
| Receivables | 19.84% | Below 49% | Money owed to the company is 19.8% of assets, under the 49% limit. | Pass |
| Revenue purity | 13.87% | Below 5% | 13.9% of revenue comes from non-compliant sources, over the 5% line. | Fail |
Five checks adapted from AAOIFI screening standards: business activity plus four balance-sheet ratios. All five must pass for ethical clearance. Every figure is arithmetic on public accounts, not judgement.
The Ethical ReadWhy It Falls Short, in Plain English
Lexicon Pharmaceuticals,'s business is in a permissible area, but its interest-bearing debt is about 34% of the company, just over the ~33% line, so it does not pass on the financial screens.
Read as at 2026-10-28. It updates when the underlying figures move, and past reads are kept below.
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The Fair Value Range
Fair value range in USD, drawn from the 2026-10-23 screen. The gold marker is the market price at the same screen. A 100.0% margin of safety to the base estimate.
Third-party analyst targets: 5 covering, consensus Buy. The average target sits +118% from the screen price.
Reading the gap · Both our model and the analysts see meaningful upside from here.
Price History & ProjectionsWhere it has been, where the models see it going. History from market close data; projection points are our fair-value estimates and third-party analyst targets, dated to the 2026-10-23 screen.
Fair value and rating are our own model estimates; the Street's range reflects third-party analyst estimates. Analysis, not advice.
The Business, in Plain WordsBiotech Revenue Rocket Still Burns Cash
Picture a small lab finally shipping product after years of trials. Lexicon shows revenue exploding more than fifteen times over, yet every pound of sales still leaks away at a 37 percent loss rate and negative return on equity. With no economic moat identified and an opportunity rating of none, the business simply fails to clear our bar despite clearing the ethical screen.
The forward multiple sits at negative 11.6 times while five analysts see a median target only modestly above the current 2.39 price. Margin of safety looks attractive on paper at fair value 3.10, but negative earnings and unknown durability of that sudden top-line jump make the discount unreliable.
Risk sits with execution on sotagliflozin and the usual biotech cash burn that can erase any apparent value quickly. Analysis, not advice.
| Forward P/E | -11.5x |
| EPS, trailing | -0.16 |
| EPS, forward | -0.19 |
| Revenue growth | -97.6%revenue is shrinking |
| Profit margin | -147.4%currently unprofitable |
| Return on equity | -40.2%not currently earning a positive return on equity |
| FCF yield | -4.59% |
| Debt to equity | 0.34minimal debt: a conservative balance sheet |
| Current ratio | 13.37comfortably covers its short-term bills |
| Beta | 1.04moves a little more than the market |
| Short interest, float | 0.14% |
| 52-week range | 1.03 - 2.68 |
| Market cap | $906M |
| Employees | 81 |
The risks · The things to watch: it's a small-cap, so the share price can swing harder than the market; as a biotechnology name, trial and regulatory outcomes can move it sharply either way.
Plain-English interpretation of our own screen data. Analysis, not advice.
Where & How to TradeLXRX trades on Nasdaq. As a listed security it is accessible through almost any international broker offering its home market. New to this, or investing from abroad? Our guide to accessing global markets covers brokers, currencies and the practical steps.
Every Entry, As Written
The analysis reads markdown. Price is trending lower. Sellers are in control and the prior trend has reversed. Price has moved down 21.1% since our last review. Ethical screening: FAIL. This security does not pass our values-based screening criteria. The risk-adjusted return profile shows good risk-adjusted returns. Our composite framework grades it C. Technically it is holding around 51% above its long-term trend line with momentum reading bullish. Over the past year the shares are up 169%. Our forward projection puts the odds of a 10% gain over the next month near 34%. The street (5 analysts) rates it none, with a mean price target of $4.
Our analysis reads markdown. Price is trending lower. Sellers are in control and the prior trend has reversed. Price has moved down 6.8% since our last review. Ethical screening: FAIL. This security does not pass our values-based screening criteria. The risk-adjusted return profile shows good risk-adjusted returns. Our composite framework grades it B. Technically it is holding around 51% above its long-term trend line with momentum reading bullish. Over the past year the shares are up 169%. Our forward projection puts the odds of a 10% gain over the next month near 34%. The street (5 analysts) rates it none, with a mean price target of $4.
The framework has shifted from accumulation to markdown since the last review. Price is trending lower. Sellers are in control and the prior trend has reversed. Price has moved down 8.4% since our last review. Ethical screening: FAIL. This security does not pass our values-based screening criteria. The risk-adjusted return profile shows good risk-adjusted returns. Our composite framework grades it B. Technically it is holding around 51% above its long-term trend line with momentum reading bullish. Over the past year the shares are up 169%. Our forward projection puts the odds of a 10% gain over the next month near 34%. The street (5 analysts) rates it none, with a mean price target of $4.
The framework has shifted from markup to accumulation since the last review. Smart money appears to be quietly building positions. This typically precedes a markup phase. Price has moved up 24.5% since our last review. Ethical screening: FAIL. This security does not pass our values-based screening criteria. The risk-adjusted return profile shows good risk-adjusted returns. Our composite framework grades it B. Technically it is holding around 51% above its long-term trend line with momentum reading bullish. Over the past year the shares are up 169%. Our forward projection puts the odds of a 10% gain over the next month near 34%. The street (5 analysts) rates it none, with a mean price target of $4.
Our analysis reads markup. Price is trending higher with momentum. The crowd has caught on and buyers are in control. Price has moved down 0.0% since our last review. Ethical screening: PASS with passing ethical screen. The risk-adjusted return profile shows good risk-adjusted returns. Our composite framework grades it B. Technically it is holding around 51% above its long-term trend line with momentum reading bullish. Over the past year the shares are up 169%. Our forward projection puts the odds of a 10% gain over the next month near 34%. The street (5 analysts) rates it none, with a mean price target of $4.
Our analysis reads markup. Price is trending higher with momentum. The crowd has caught on and buyers are in control. Price has moved down 0.0% since our last review. Ethical screening: PASS with passing ethical screen (70). The risk-adjusted return profile shows good risk-adjusted returns.
Our analysis reads markup. Price is trending higher with momentum. The crowd has caught on and buyers are in control. Ethical screening: PASS with passing ethical screen (70). The risk-adjusted return profile shows good risk-adjusted returns.
Each entry above was written on its date, before the outcome. A journal you can prune is not a journal.
Screened names in the same industry · explore each on its own page.
| Period | Price then | Price return | Divs per share | $1,000 became | Total return |
|---|---|---|---|---|---|
| 1 month | $2.31 | -18.4% | · | $816 | -18.4% |
| 2 months | $1.72 | +9.6% | · | $1,096 | +9.6% |
| 3 months | $1.72 | +9.6% | · | $1,096 | +9.6% |
| 6 months | $1.32 | +42.8% | · | $1,428 | +42.8% |
| 1 year | $0.70 | +169.3% | · | $2,693 | +169.3% |
| 2 years | $1.90 | -0.8% | · | $992 | -0.8% |
| 3 years | $2.83 | -33.4% | · | $666 | -33.4% |
| 5 years | $4.87 | -61.3% | · | $387 | -61.3% |
Historical returns from market close data. Past performance does not guarantee future results.
This entry now belongs to the ledger. Whatever LXRX does next, these words stay.
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