Updated 14:02 GMT, 29 Oct 2026 SPX 7,717.63 -0.34% NDX 29,430.34 -1.28% VIX 16.92 +0.06% GOLD 4,037.70 -0.34% CL 100.06 -2.65% BTC 80,234.72 -1.27%
NAS100 29,430 −1.28% S&P 7,718 −0.34% GOLD $4,038 −0.34% BTC $80,235 −1.27% VIX 16.92 +0.06% latest tape · as of 14:02 UTC
The Screen · Healthcare

Syros Pharmaceuticals, Inc.

SYRS · PNK · USD · Market cap $5,366

FAIL · Does not pass the screen
0.00 USD

Price as of 23 Oct 2026Daily close, not a live quoteLast reviewed 6 days ago

Screened 2026-10-23 · the tape above runs as of 14:02 UTC · two dates, stated on purpose · verdict and workings shown in full · never trimmed

Key facts today

  • Price0.00 USD at the 23 Oct 2026 close
  • Ethical screenDoes not pass
  • Last reviewed23 Oct 2026 (6 days ago)

A summary of the dated readings below, not a live quote and not advice.

PRICE · FAIR-VALUE RANGE1M3M6MYTD1Y3Y5Y

What this means: price 0.00 against the desk's fair-value range, over the last year.

Current read
Markdown ?
Screened · screened 2026-10-23
  • Trend Markdown
  • Insiders no filings inside 60 days, left as found
  • Positioning no disclosures inside 60 days, left as found
  • Options no verdict drawn today, left as found
  • Ethical does not pass the values gate
Price0.00 USD
Our investment reviews on this name
2026-10-18Read Markdown0.00+0.0% to today Markup gives way to Markdown
2026-07-02Read Markup0.00+0.0% to today ✓First review on file: Markup

Our analytic regime reads on this name, dated and marked against the screened price. Small sample per name, and separate from the daily-framework accuracy on the Track Record page.

The full research record, in depth, below
The Label · The Season, Not the Day

This name holds its markdown label.

Syros Pharmaceuticals, Inc. holds its Markdown at $0.00. Consolidating, no directional conviction, held for 23 days.

As held on the ledger · 2026-10-23
PhaseMarkdown · caution
Quantitative stateConsolidating, no directional conviction, held for 23 days
Price at the screen$0.00
Valuation0.00 trailing · 0.00 forward price to earnings
Values screenFAIL
The Workings

Five Screens, Shown in Full

Does not pass. Debt ratio

TestFigureLimitWhat it meansStatus
Business activity Permissible Core business clean Its core business isn't built on prohibited lines: no gambling, alcohol, tobacco, weapons, or interest-based lending. Pass
Debt load 1,122,363.03% Below 33% Interest-bearing debt is 1,122,363.0% of its assets, above the one-third ceiling the screen allows. Fail
Interest-bearing cash 1,086,004.47% Below 33% Interest-bearing cash and securities are 1,086,004.5% of assets, above the one-third limit. Fail
Receivables 0.00% Below 49% Money owed to the company is 0.0% of assets, under the 49% limit. Pass
Revenue purity 68.60% Below 5% 68.6% of revenue comes from non-compliant sources, over the 5% line. Fail

Five checks adapted from AAOIFI screening standards: business activity plus four balance-sheet ratios. All five must pass for ethical clearance. Every figure is arithmetic on public accounts, not judgement.

The Ethical Read

Why It Falls Short, in Plain English

Syros Pharmaceuticals,'s business is in a permissible area, but its interest-bearing debt is about 1122363% of the company, well over the ~33% line, so it does not pass on the financial screens.

Read as at 2026-10-28. It updates when the underlying figures move, and past reads are kept below.

Follow this verdict

Get an email when SYRS's ethical verdict changes

Today SYRS does not pass the screen. If new figures move it to a pass, we send you one short email with the before and after. Verdicts change rarely, so you may not hear from us for a long time.

Free, no account needed. Every email has a link to stop.

The Business, in Plain Words
The fundamentals · plain-English read
Forward P/E0.0x
Trailing P/E0.0x
EPS, trailing-3.07
EPS, forward-2.61
Revenue growth+0.0%revenue is shrinking
Profit margin0.0%currently unprofitable
Return on equity-777.0%not currently earning a positive return on equity
Debt to equity0.00minimal debt: a conservative balance sheet
Market cap$5,366

The risks · The things to watch: it's a small-cap, so the share price can swing harder than the market.

Plain-English interpretation of our own screen data. Analysis, not advice.

Where & How to Trade

SYRS trades on PNK. As a listed security it is accessible through almost any international broker offering its home market. New to this, or investing from abroad? Our guide to accessing global markets covers brokers, currencies and the practical steps.

The Dated Journal · Newest First, Never Edited

Every Entry, As Written

2026-10-18 Markdown · changed $0.00 +0.0% Entry 7

The framework has shifted from markup to markdown since the last review. Price is trending lower. Sellers are in control and the prior trend has reversed. Price has moved down 0.0% since our last review. Ethical screening: FAIL. This security does not pass our values-based screening criteria. The risk-adjusted return profile shows excellent risk-adjusted returns. Our composite framework grades it C. Technically it is sitting below its long-term trend line with momentum reading bearish. Over the past year the shares are down 99%. Our forward projection puts the odds of a 10% gain over the next month near 3%. The street (4 analysts) rates it none, with a mean price target of $9.

2026-10-11 Markup $0.00 +0.0% Entry 6

The analysis reads markup. Price is trending higher with momentum. The crowd has caught on and buyers are in control. Price has moved down 0.0% since our last review. Ethical screening: FAIL. This security does not pass our values-based screening criteria. The risk-adjusted return profile shows excellent risk-adjusted returns. Our composite framework grades it D. Technically it is sitting below its long-term trend line with momentum reading bearish. Over the past year the shares are down 99%. Our forward projection puts the odds of a 10% gain over the next month near 3%. The street (4 analysts) rates it none, with a mean price target of $9.

2026-09-14 Markup $0.00 +0.0% Entry 5

Our analysis reads markup. Price is trending higher with momentum. The crowd has caught on and buyers are in control. Price has moved down 0.0% since our last review. Ethical screening: FAIL. This security does not pass our values-based screening criteria. The risk-adjusted return profile shows excellent risk-adjusted returns. Our composite framework grades it D. Technically it is sitting below its long-term trend line with momentum reading bearish. Over the past year the shares are down 99%. Our forward projection puts the odds of a 10% gain over the next month near 3%. The street (4 analysts) rates it none, with a mean price target of $9.

2026-08-14 Markup $0.00 +0.0% Entry 4

Our analysis reads markup. Price is trending higher with momentum. The crowd has caught on and buyers are in control. Price has moved down 0.0% since our last review. Ethical screening: FAIL. This security does not pass our values-based screening criteria. The risk-adjusted return profile shows excellent risk-adjusted returns. Our composite framework grades it D. Technically it is sitting below its long-term trend line with momentum reading bearish. Over the past year the shares are down 99%. Our forward projection puts the odds of a 10% gain over the next month near 3%. The street (4 analysts) rates it none, with a mean price target of $9.

2026-07-18 Markup $0.00 +0.0% Entry 3

Our analysis reads markup. Price is trending higher with momentum. The crowd has caught on and buyers are in control. Price has moved down 0.0% since our last review. Ethical screening: FAIL. This security does not pass our values-based screening criteria. The risk-adjusted return profile shows excellent risk-adjusted returns. Our composite framework grades it D. Technically it is sitting below its long-term trend line with momentum reading bearish. Over the past year the shares are down 99%. Our forward projection puts the odds of a 10% gain over the next month near 3%. The street (4 analysts) rates it none, with a mean price target of $9.

2026-07-03 Markup $0.00 +0.0% Entry 2

Our analysis reads markup. Price is trending higher with momentum. The crowd has caught on and buyers are in control. Price has moved down 0.0% since our last review. Ethical screening: FAIL. This security does not pass our values-based screening criteria. The risk-adjusted return profile shows excellent risk-adjusted returns.

2026-07-02 Markup $0.00 Entry 1

Our analysis reads markup. Price is trending higher with momentum. The crowd has caught on and buyers are in control. Ethical screening: FAIL. This security does not pass our values-based screening criteria. The risk-adjusted return profile shows excellent risk-adjusted returns.

Each entry above was written on its date, before the outcome. A journal you can prune is not a journal.

The Insider Ledger · Form 4 Filings, As Filed
Most recent filings · SYRS
DateInsiderTitleTypeSharesValue
2024-12-02 SIMONIAN NANCY A Director 37,070 $10,016
2024-11-25 SIMONIAN NANCY A Director 134,713 $35,739
2024-11-19 QUIRK GERALD E. Officer 46,657 $12,915
2024-11-18 ROTH DAVID A M.D. Officer 12,099 $2,382
2024-11-18 STEPHENS KRISTIN Officer 36,133 $7,949
2024-11-18 CHEE CONLEY Chief Executive Officer 134,797 $26,932
2024-11-18 HAAS JASON Chief Financial Officer 137,803 $28,980
2024-10-31 SIMONIAN NANCY A Director 40,125 ·
2024-10-31 ROTH DAVID A M.D. Officer 18,875 ·
2024-10-31 STEPHENS KRISTIN Officer 17,000 ·

Public filings, recorded as found. The full tape lives at Insider Intelligence.

What Holding Actually Paid · Price Plus Dividends
If $1,000 had been placed · historical, not a promise
PeriodPrice thenPrice returnDivs per share$1,000 becameTotal return
1 month $0.00 +0.0% · $1,000 +0.0%
2 months $0.00 -50.0% · $500 -50.0%
3 months $0.00 +0.0% · $1,000 +0.0%
6 months $0.00 -60.0% · $400 -60.0%
1 year $0.03 -99.2% · $8 -99.2%
2 years $5.15 -100.0% · $0 -100.0%
3 years $3.55 -100.0% · $0 -100.0%
5 years $58.80 -100.0% · $0 -100.0%

Historical returns from market close data. Past performance does not guarantee future results.

The Ledger's Promise

This entry now belongs to the ledger. Whatever SYRS does next, these words stay.

Syros Pharmaceuticals, Inc. · SYRS · Markdown · $0.00
Recorded 2026-10-23 · before the outcome · scored mechanically

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Screening is research, not a fatwa and not financial advice. Figures are drawn from public accounts at the screen date shown. Always manage your risk.

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