The framework has shifted from markup to accumulation since the last review. Smart money appears to be quietly building positions. This typically precedes a markup phase. Price has moved up 23.0% since our last review. Ethical screening: PASS with passing ethical screen. The risk-adjusted return profile shows excellent risk-adjusted returns. Our composite framework grades it C, carrying a low risk profile. Technically it is holding around 19% above its long-term trend line with momentum reading oversold. Over the past year the shares are up 67%. Our forward projection puts the odds of a 10% gain over the next month near 38%. The street (8 analysts) rates it none, with a mean price target of $64.
Kiniksa Pharmaceuticals International, plc
KNSA · Nasdaq · USD · Market cap $3.6B · 366 employees
Kiniksa Pharmaceuticals International, plc, a biopharmaceutical company, develops and commercializes medical therapies in the United States, the United Kingdom, and internationally.
PASS · Titan Ethical · score 70.0Screen close, 2026-09-21 · not a live quote
Screened 2026-09-21 · the tape above runs as of 11:00 UTC · two dates, stated on purpose · verdict and workings shown in full · never trimmed
What this means: price 78.13 against the desk's fair-value range, base estimate 67.04, over the last year.
- Trend Markdown
- Insiders no filings inside 60 days, left as found
- Positioning no disclosures inside 60 days, left as found
- Options no verdict drawn today, left as found
- Ethical passes the values gate
Our analytic regime reads on this name, dated and marked against the screened price. Small sample per name, and separate from the daily-framework accuracy on the Track Record page.
This name holds its markdown label.
Kiniksa Pharmaceuticals International, plc holds its Markdown at $78.13. The statistical read favours the sellers, held for 21 days.
| Phase | Markdown · caution |
| Quantitative state | The statistical read favours the sellers, held for 21 days |
| Price at the screen | $78.13 |
| Valuation | 78.92 trailing · 48.30 forward price to earnings |
| Values screen | PASS · score 70.0 |
| Beta | 0.09 |
Five Screens, Shown in Full
Full pass across all five screens. This security clears the Titan Ethical Standard: its business and its balance sheet both stay inside the lines.
| Test | Figure | Limit | What it means | Status |
|---|---|---|---|---|
| Business activity | Permissible | Core business clean | Its core business isn't built on prohibited lines: no gambling, alcohol, tobacco, weapons, or interest-based lending. | Pass |
| Debt load | 1.24% | Below 33% | Interest-bearing debt is just 1.2% of its assets, well under the one-third ceiling: it does not run on borrowed money. | Pass |
| Interest-bearing cash | 32.54% | Below 33% | Cash held in interest-bearing accounts and securities is 32.5% of assets, under the one-third limit. | Pass |
| Receivables | 23.73% | Below 49% | Money owed to the company is 23.7% of assets, under the 49% limit. | Pass |
| Revenue purity | 0.00% | Below 5% | Only 0.0% of revenue comes from non-compliant sources, under the 5% line. | Pass |
Five checks adapted from AAOIFI screening standards: business activity plus four balance-sheet ratios. All five must pass for ethical clearance. Every figure is arithmetic on public accounts, not judgement.
What the Numbers Say It Is WorthThe Fair Value Range
Fair value range in USD, drawn from the 2026-09-21 screen. The gold marker is the market price at the same screen. The price runs 14.2% above the base estimate.
Third-party analyst targets: 8 covering, consensus None. The average target sits +26% from the screen price.
Reading the gap · Our more conservative model reads it as fully-to-richly valued here, while the Street is more bullish: a quality-at-a-fair-price name rather than a deep-value one.
Price History & ProjectionsWhere it has been, where the models see it going. History from market close data; projection points are our fair-value estimates and third-party analyst targets, dated to the 2026-09-21 screen.
Fair value and rating are our own model estimates; the Street's range reflects third-party analyst estimates. Analysis, not advice.
The Business, in Plain WordsHigh growth drug maker priced above its worth
Every patient who gets relief from a new therapy like ARCALYST shows how specialist drug developers can move fast. Kiniksa has posted 56 percent revenue growth, a 10 percent profit margin and 14 percent return on equity, yet the shares trade at 63.95 dollars against a fair value of 52.98 dollars. That leaves a negative margin of safety and a forward multiple of 37.6 times earnings.
We pass. The strong buy consensus and 68 dollar median target already assume the growth story runs without a hitch, but nothing in the numbers suggests the current price offers any cushion if momentum fades.
Risks sit in typical biotech execution, competition and the chance that peak sales fall short of lofty expectations. Currency and regulatory shifts add further uncertainty in this field. Analysis, not advice.
| Forward P/E | 48.3xfairly priced for its growth rate |
| Trailing P/E | 78.9xexpensive: the price assumes strong growth ahead |
| EPS, trailing | 0.99 |
| EPS, forward | 1.62 |
| Revenue growth | +55.4%growing very fast |
| Profit margin | 9.6%thin but positive margins |
| Return on equity | 14.0%a solid return on shareholder capital |
| FCF yield | 2.15% |
| Debt to equity | 1.36a meaningful debt load worth watching |
| Current ratio | 3.90comfortably covers its short-term bills |
| Beta | 0.09barely tracks the market's swings |
| Short interest, float | 0.09% |
| 52-week range | 35.20 - 82.94 |
| Market cap | $3.6B |
| Employees | 366 |
The risks · The things to watch: its business and earnings are exposed to United Kingdom and to currency swings; as a drug manufacturers - specialty & generic name, trial and regulatory outcomes can move it sharply either way.
Plain-English interpretation of our own screen data. Analysis, not advice.
Where & How to TradeKNSA trades on Nasdaq (the company is based in United Kingdom). As a listed security it is accessible through almost any international broker offering its home market. New to this, or investing from abroad? Our guide to accessing global markets covers brokers, currencies and the practical steps.
Every Entry, As Written
The framework has shifted from distribution to markup since the last review. Price is trending higher with momentum. The crowd has caught on and buyers are in control. Price has moved up 23.2% since our last review. Ethical screening: PASS with passing ethical screen. The risk-adjusted return profile shows excellent risk-adjusted returns. Our composite framework grades it C, carrying a low risk profile. Technically it is holding around 19% above its long-term trend line with momentum reading oversold. Over the past year the shares are up 67%. Our forward projection puts the odds of a 10% gain over the next month near 38%. The street (8 analysts) rates it none, with a mean price target of $64.
The framework reads distribution. Smart money appears to be selling into strength. Institutional holders may be rotating out. Price has moved down 0.0% since our last review. Ethical screening: PASS with passing ethical screen. The risk-adjusted return profile shows excellent risk-adjusted returns. Our composite framework grades it C, carrying a low risk profile. Technically it is holding around 19% above its long-term trend line with momentum reading oversold. Over the past year the shares are up 67%. Our forward projection puts the odds of a 10% gain over the next month near 38%. The street (8 analysts) rates it none, with a mean price target of $64.
The framework reads distribution. Smart money appears to be selling into strength. Institutional holders may be rotating out. Price has moved down 0.0% since our last review. Ethical screening: PASS with passing ethical screen (70). The risk-adjusted return profile shows excellent risk-adjusted returns.
The framework reads distribution. Smart money appears to be selling into strength. Institutional holders may be rotating out. Ethical screening: PASS with passing ethical screen (70). The risk-adjusted return profile shows excellent risk-adjusted returns.
Each entry above was written on its date, before the outcome. A journal you can prune is not a journal.
- Kiniksa Pharmaceuticals Stock Rallies 41% in Three Months: Here's Why Zacks · 5d ago
- Biopharmaceutical Leader Kiniksa Poised To Hit New Buy Point After Big Revenue Beat Investor's Business Daily · 12d ago
- TGTX Stock Outperforms 95% of Stocks. Here's Why. Investor's Business Daily · 29d ago
- Kiniksa's Sales Are Expected To Decline — Why That's All According To Plan Investor's Business Daily · 21 Aug 2026
- Three Biotech Stocks Stick Out With Their Stellar Charts Investor's Business Daily · 21 Aug 2026
Headlines from third-party outlets, linked for reference: not our reporting, not advice.
Screened names in the same industry · explore each on its own page.
| Period | Price then | Price return | Divs per share | $1,000 became | Total return |
|---|---|---|---|---|---|
| 1 month | $58.37 | -14.9% | · | $851 | -14.9% |
| 2 months | $47.08 | +5.5% | · | $1,055 | +5.5% |
| 3 months | $46.07 | +7.8% | · | $1,078 | +7.8% |
| 6 months | $41.01 | +21.1% | · | $1,211 | +21.1% |
| 1 year | $29.77 | +66.9% | · | $1,669 | +66.9% |
| 2 years | $19.22 | +158.4% | · | $2,584 | +158.4% |
| 3 years | $15.05 | +230.0% | · | $3,300 | +230.0% |
| 5 years | $14.86 | +234.3% | · | $3,343 | +234.3% |
Historical returns from market close data. Past performance does not guarantee future results.
This entry now belongs to the ledger. Whatever KNSA does next, these words stay.
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Join the deskScreening is research, not a fatwa and not financial advice. Figures are drawn from public accounts at the screen date shown. Always manage your risk.