The framework has shifted from markup to markdown since the last review. Price is trending lower. Sellers are in control and the prior trend has reversed. Price has moved down 2.0% since our last review. Ethical screening: FAIL. This security does not pass our values-based screening criteria. The risk-adjusted return profile shows excellent risk-adjusted returns. Our composite framework grades it B, carrying a low risk profile. Technically it is holding around 20% above its long-term trend line with momentum reading overbought. Over the past year the shares are up 120%. Our forward projection puts the odds of a 10% gain over the next month near 38%. The street (10 analysts) rates it strong buy, with a mean price target of $272. Insiders have been net sellers over the past quarter.
Ligand Pharmaceuticals Incorporated
LGND · Nasdaq · USD · Market cap $5.7B · 47 employees
Ligand Pharmaceuticals Incorporated, a biopharmaceutical company, develops and licenses biopharmaceutical assets worldwide.
FAIL · Does not pass the screenAt the last full screen
2026-09-11
Screened 2026-09-11 · the tape above runs as of 09:00 UTC · two dates, stated on purpose · verdict and workings shown in full · never trimmed
This name holds its markdown label.
Ligand Pharmaceuticals Incorporated holds its Markdown at $284.47. Consolidating, no directional conviction, held for 1 days.
| Phase | Markdown · caution |
| Quantitative state | Consolidating, no directional conviction, held for 1 days |
| Price at the screen | $284.47 |
| Valuation | 29.30 trailing · 23.84 forward price to earnings |
| Values screen | FAIL · score 70.0 |
| Beta | 0.98 |
Five Screens, Shown in Full
Does not pass. Revenue purity
| Test | Figure | Limit | What it means | Status |
|---|---|---|---|---|
| Business activity | Permissible | Core business clean | Its core business isn't built on prohibited lines: no gambling, alcohol, tobacco, weapons, or interest-based lending. | Pass |
| Debt load | 28.93% | Below 33% | Interest-bearing debt is just 28.9% of its assets, well under the one-third ceiling: it does not run on borrowed money. | Pass |
| Interest-bearing cash | 12.62% | Below 33% | Cash held in interest-bearing accounts and securities is 12.6% of assets, under the one-third limit. | Pass |
| Receivables | 15.03% | Below 49% | Money owed to the company is 15.0% of assets, under the 49% limit. | Pass |
| Revenue purity | 5.09% | Below 5% | 5.1% of revenue comes from non-compliant sources, over the 5% line. | Fail |
Five checks adapted from AAOIFI screening standards: business activity plus four balance-sheet ratios. All five must pass for ethical clearance. Every figure is arithmetic on public accounts, not judgement.
What the Numbers Say It Is WorthThe Fair Value Range
Fair value range in USD, drawn from the 2026-09-11 screen. The gold marker is the market price at the same screen. A 6.8% margin of safety to the base estimate.
Third-party analyst targets: 11 covering, consensus None. The average target sits +21% from the screen price.
Reading the gap · Both our model and the analysts see meaningful upside from here.
Price History & ProjectionsWhere it has been, where the models see it going. History from market close data; projection points are our fair-value estimates and third-party analyst targets, dated to the 2026-09-11 screen.
Fair value and rating are our own model estimates; the Street's range reflects third-party analyst estimates. Analysis, not advice.
The Business, in Plain WordsBiotech licensor offers strong margins yet no margin of safety
Picture a company that simply licenses drug formulas rather than running full clinical trials. Ligand does exactly that and posts a 56 percent profit margin with 14 percent revenue growth and 17 percent return on equity. Those numbers look solid on paper yet our fair value sits at 281.87 while the shares trade at 303.39, giving a negative margin of safety and a clear none rating on opportunity.
The business model keeps overhead low by partnering assets such as EVOMELA and KYPROLIS into approved treatments worldwide. Forward earnings sit at 26.3 times and ten analysts still carry a strong buy stance with a 310 median target. Ethical screening clears the name without issue, which removes one common reason to step aside.
Valuation risk remains the decisive factor here. A modest premium to fair value can quickly reverse in a sector where royalty streams face patent cliffs and partner concentration. The absence of any moat rating adds further uncertainty around durability. Analysis, not advice.
| Forward P/E | 23.8xcheap for a company growing this fast |
| Trailing P/E | 29.3xa premium valuation |
| EPS, trailing | 9.71 |
| EPS, forward | 11.93 |
| Revenue growth | +33.7%strong top-line growth |
| Profit margin | 67.9%highly profitable on every dollar of sales |
| Return on equity | 22.0%an exceptional return on shareholder capital |
| FCF yield | 2.46% |
| Debt to equity | 1.17a meaningful debt load worth watching |
| Current ratio | 31.18comfortably covers its short-term bills |
| Beta | 0.98steadier than the market |
| Short interest, float | 0.15% |
| 52-week range | 161.82 - 326.63 |
| Market cap | $5.7B |
| Employees | 47 |
The risks · The things to watch: as a biotechnology name, trial and regulatory outcomes can move it sharply either way.
Plain-English interpretation of our own screen data. Analysis, not advice.
Where & How to TradeLGND trades on Nasdaq. As a listed security it is accessible through almost any international broker offering its home market. New to this, or investing from abroad? Our guide to accessing global markets covers brokers, currencies and the practical steps.
Every Entry, As Written
The framework reads markup. Price is trending higher with momentum. The crowd has caught on and buyers are in control. Price has moved up 12.5% since our last review. Ethical screening: FAIL. This security does not pass our values-based screening criteria. The risk-adjusted return profile shows excellent risk-adjusted returns. Our composite framework grades it B, carrying a low risk profile. Technically it is holding around 20% above its long-term trend line with momentum reading overbought. Over the past year the shares are up 120%. Our forward projection puts the odds of a 10% gain over the next month near 38%. The street (10 analysts) rates it strong buy, with a mean price target of $272.
The framework reads markup. Price is trending higher with momentum. The crowd has caught on and buyers are in control. Price has moved down 0.0% since our last review. Ethical screening: PASS with passing ethical screen. The risk-adjusted return profile shows excellent risk-adjusted returns. Our composite framework grades it B, carrying a low risk profile. Technically it is holding around 20% above its long-term trend line with momentum reading overbought. Over the past year the shares are up 120%. Our forward projection puts the odds of a 10% gain over the next month near 38%. The street (10 analysts) rates it strong buy, with a mean price target of $272.
The framework reads markup. Price is trending higher with momentum. The crowd has caught on and buyers are in control. Price has moved down 0.0% since our last review. Ethical screening: PASS with passing ethical screen (70). The risk-adjusted return profile shows excellent risk-adjusted returns.
The framework reads markup. Price is trending higher with momentum. The crowd has caught on and buyers are in control. Ethical screening: PASS with passing ethical screen (70). The risk-adjusted return profile shows excellent risk-adjusted returns.
Each entry above was written on its date, before the outcome. A journal you can prune is not a journal.
Screened names in the same industry · explore each on its own page.
| Date | Insider | Title | Type | Shares | Value |
|---|---|---|---|---|---|
| 2026-09-10 | Zimmermann Martine | Dir | S - Sale | 1,200 | $342,000 |
| 2026-08-12 | Espinoza Octavio | CFO | S - Sale+OE | 31,641 | $9,241,229 |
| 2026-08-12 | Haas Jason | Dir | S - Sale+OE | 7,138 | $2,090,062 |
Public filings, recorded as found. The full tape lives at Insider Intelligence.
| Period | Price then | Price return | Divs per share | $1,000 became | Total return |
|---|---|---|---|---|---|
| 1 month | $220.48 | +12.9% | · | $1,129 | +12.9% |
| 2 months | $204.92 | +21.5% | · | $1,215 | +21.5% |
| 3 months | $211.48 | +17.7% | · | $1,177 | +17.7% |
| 6 months | $183.13 | +36.0% | · | $1,360 | +36.0% |
| 1 year | $113.42 | +119.5% | · | $2,195 | +119.5% |
| 2 years | $79.53 | +213.1% | · | $3,131 | +213.1% |
| 3 years | $73.76 | +237.6% | · | $3,376 | +237.6% |
| 5 years | $77.12 | +222.9% | · | $3,229 | +222.9% |
Historical returns from market close data. Past performance does not guarantee future results.
This entry now belongs to the ledger. Whatever LGND does next, these words stay.
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