The framework has shifted from markup to markdown since the last review. Price is trending lower. Sellers are in control and the prior trend has reversed. Price has moved up 7.3% since our last review. Ethical screening: FAIL. This security does not pass our values-based screening criteria. The risk-adjusted return profile shows excellent risk-adjusted returns. Our composite framework grades it C. Technically it is holding around 66% above its long-term trend line with momentum reading bearish. Over the past year the shares are up 395%. Our forward projection puts the odds of a 10% gain over the next month near 39%. The street (12 analysts) rates it strong buy, with a mean price target of $142. Insiders have been net sellers over the past quarter.
Oruka Therapeutics, Inc.
ORKA · Nasdaq · USD · Market cap $6.1B · 68 employees
Oruka Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on developing novel monoclonal antibody therapeutics for psoriasis (PsO), and other inflammatory and immunology (I&I) indications.
Not yet scoredAt the last full screen
2026-09-15
Screened 2026-09-15 · the tape above runs as of 11:00 UTC · two dates, stated on purpose · verdict and workings shown in full · never trimmed
This name holds its markdown label.
Oruka Therapeutics, Inc. holds its Markdown at $92.20. The statistical read favours the sellers, held for 32 days.
| Phase | Markdown · caution |
| Quantitative state | The statistical read favours the sellers, held for 32 days |
| Price at the screen | $92.20 |
| Valuation | N/A trailing · -32.21 forward price to earnings |
| Values screen | Not scored · score 70.0 |
| Beta | -0.21 |
Five Screens, Shown in Full
This security has not been fully scored against the values screen yet.
| Test | Figure | Limit | What it means | Status |
|---|---|---|---|---|
| Business activity | Permissible | Core business clean | Its core business isn't built on prohibited lines: no gambling, alcohol, tobacco, weapons, or interest-based lending. | Pass |
| Debt load | 0.40% | Below 33% | Interest-bearing debt is just 0.4% of its assets, well under the one-third ceiling: it does not run on borrowed money. | Pass |
| Interest-bearing cash | 29.17% | Below 33% | Cash held in interest-bearing accounts and securities is 29.2% of assets, under the one-third limit. | Pass |
| Receivables | 9.61% | Below 49% | Money owed to the company is 9.6% of assets, under the 49% limit. | Pass |
| Revenue purity | Excluded | Below 5% | of revenue comes from non-compliant sources, over the 5% line. | Fail |
Five checks adapted from AAOIFI screening standards: business activity plus four balance-sheet ratios. All five must pass for ethical clearance. Every figure is arithmetic on public accounts, not judgement.
What the Numbers Say It Is WorthThe Fair Value Range
Fair value range in USD, drawn from the 2026-09-15 screen. The gold marker is the market price at the same screen. A 68.7% margin of safety to the base estimate.
Third-party analyst targets: 12 covering, consensus Strong Buy. The average target sits +69% from the screen price.
Reading the gap · Both our model and the analysts see meaningful upside from here.
Price History & ProjectionsWhere it has been, where the models see it going. History from market close data; projection points are our fair-value estimates and third-party analyst targets, dated to the 2026-09-15 screen.
Fair value and rating are our own model estimates; the Street's range reflects third-party analyst estimates. Analysis, not advice.
The Business, in Plain WordsClinical Stage Drug Developer Fails Basic Screen
A company chasing new antibodies for psoriasis sounds promising until the numbers arrive. Oruka sits at a 93 dollar share price against our 141 dollar fair value, yet forward earnings sit at minus 37 times with zero profit margin and return on equity of minus 27 percent. The ethical screen returns insufficient data, which alone ends the conversation for us.
We pass because no workable financial ratios exist to judge durability or governance. Analyst targets cluster near 142 dollars on a strong buy consensus, but that optimism rests on future trial success that has not yet produced cash or earnings. Unknown competitive edge adds another layer of opacity.
Risks centre on typical early stage biotech outcomes: trial failure, dilution, and total loss of capital. Currency and sector swings matter less here than the simple absence of usable data. Analysis, not advice.
| Forward P/E | -32.2x |
| EPS, trailing | -2.04 |
| EPS, forward | -2.86 |
| Profit margin | 0.0%currently unprofitable |
| Return on equity | -18.2%not currently earning a positive return on equity |
| FCF yield | -1.07% |
| Debt to equity | 0.23minimal debt: a conservative balance sheet |
| Current ratio | 38.51comfortably covers its short-term bills |
| Beta | -0.21barely tracks the market's swings |
| Short interest, float | 0.17% |
| 52-week range | 14.67 - 115.52 |
| Market cap | $6.1B |
| Employees | 68 |
The risks · The things to watch: as a biotechnology name, trial and regulatory outcomes can move it sharply either way.
Plain-English interpretation of our own screen data. Analysis, not advice.
Where & How to TradeORKA trades on Nasdaq. As a listed security it is accessible through almost any international broker offering its home market. New to this, or investing from abroad? Our guide to accessing global markets covers brokers, currencies and the practical steps.
Every Entry, As Written
The framework has shifted from markdown to markup since the last review. Price is trending higher with momentum. The crowd has caught on and buyers are in control. Price has moved up 32.6% since our last review. Ethical screening: FAIL. This security does not pass our values-based screening criteria. The risk-adjusted return profile shows excellent risk-adjusted returns. Our composite framework grades it C. Technically it is holding around 66% above its long-term trend line with momentum reading bearish. Over the past year the shares are up 395%. Our forward projection puts the odds of a 10% gain over the next month near 39%. The street (12 analysts) rates it strong buy, with a mean price target of $142.
The framework reads markdown. Price is trending lower. Sellers are in control and the prior trend has reversed. Price has moved down 0.0% since our last review. Ethical screening: FAIL. This security does not pass our values-based screening criteria. The risk-adjusted return profile shows good risk-adjusted returns. Our composite framework grades it C. Technically it is holding around 66% above its long-term trend line with momentum reading bearish. Over the past year the shares are up 395%. Our forward projection puts the odds of a 10% gain over the next month near 39%. The street (12 analysts) rates it strong buy, with a mean price target of $142.
The framework reads markdown. Price is trending lower. Sellers are in control and the prior trend has reversed. Price has moved down 0.0% since our last review. Ethical screening: FAIL. This security does not pass our values-based screening criteria. The risk-adjusted return profile shows good risk-adjusted returns.
The framework reads markdown. Price is trending lower. Sellers are in control and the prior trend has reversed. Ethical screening: FAIL. This security does not pass our values-based screening criteria. The risk-adjusted return profile shows good risk-adjusted returns.
Each entry above was written on its date, before the outcome. A journal you can prune is not a journal.
Screened names in the same industry · explore each on its own page.
| Date | Insider | Title | Type | Shares | Value |
|---|---|---|---|---|---|
| 2026-08-14 | Quinlan Paul T | GC | S - Sale+OE | 52,000 | $5,641,409 |
| 2026-08-13 | Agarwal Arjun | SVP, Finance | S - Sale+OE | 10,000 | $1,066,572 |
Public filings, recorded as found. The full tape lives at Insider Intelligence.
| Period | Price then | Price return | Divs per share | $1,000 became | Total return |
|---|---|---|---|---|---|
| 1 month | $65.68 | -0.7% | · | $994 | -0.7% |
| 2 months | $59.58 | +9.5% | · | $1,095 | +9.5% |
| 3 months | $31.99 | +104.0% | · | $2,040 | +104.0% |
| 6 months | $30.21 | +116.0% | · | $2,160 | +116.0% |
| 1 year | $13.19 | +394.7% | · | $4,947 | +394.7% |
| 2 years | $20.65 | +215.9% | $19.36 | $4,097 | +309.7% |
| 3 years | $13.29 | +390.8% | $19.36 | $6,364 | +536.4% |
| 5 years | $23.75 | +174.7% | $19.36 | $3,562 | +256.2% |
Historical returns from market close data. Past performance does not guarantee future results.
This entry now belongs to the ledger. Whatever ORKA does next, these words stay.
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