How this company measures up on the fundamentals that matter
Aldeyra Therapeutics, Inc., a biotechnology company, discovers and develops therapies designed to treat immune-mediated diseases. Its lead product candidate is reproxalap, a reactive aldehyde species (RASP) modulator, which is in Phase III clinical trial for the treatment of dry eye disease and allergic conjunctivitis; and ADX-2191, a dihydrofolate reductase inhibitor for the treatment of primary vitreoretinal lymphoma and retinitis pigmentosa. The company also develops ADX-629, an orally administered RASP modulator that is in Phase 2 clinical trials for the treatment of COVID-19, atopic asthma, psoriasis, and alcohol intoxication. In addition, it develops preclinical RASP platforms, including ADX 248, ADX 246, and other novel RASP modulators for the treatment of various diseases associated with RASP. The company was formerly known as Aldexa Therapeutics, Inc. and changed its name to Aldeyra Therapeutics, Inc. in March 2014. Aldeyra Therapeutics, Inc. was incorporated in 2004 and is based in Lexington, Massachusetts.
Five compliance checks based on AAOIFI standards — all must pass for ethical clearance
Statistical analysis of price behaviour, risk, and market regime — independent of fundamental data
Trading characteristics and market positioning
Balance sheet strength and cash generation — the foundation of long-term value
SEC Form 4 filings — what company insiders are buying and selling
| Date | Insider | Title | Type | Shares | Value |
|---|---|---|---|---|---|
| 2026-03-19 | DOUGLAS RICHARD H | Director | 70,000 | $128,100 | |
| 2026-03-18 | ALFIERI MICHAEL L | Chief Financial Officer | 5,000 | $7,100 | |
| 2025-08-13 | ALFIERI MICHAEL L | Chief Financial Officer | 2,500 | $13,250 | |
| 2025-08-11 | MACHATHA STEPHEN | Officer | 22,073 | $113,713 | |
| 2025-04-03 | PERCEPTIVE ADVISORS L L C | Beneficial Owner of more than 10% of a Class of Security | 3,400,000 | $4,828,000 | |
| 2024-08-12 | MACHATHA STEPHEN | Officer | 16,041 | $75,975 | |
| 2024-08-12 | GREENBERG BRUCE | Chief Financial Officer | 10,834 | $51,313 |
Data sourced from public filings and market feeds. Not financial advice. Updated: 2026-05-13