CUE
Cue Biopharma, Inc.
Healthcare · Biotechnology · NCM
$22.97
Close 2026-05-15
✓ ETHICAL PASS
HIGH
Data Confidence: 86%
Full financial profile available
Market Cap
$74.8M
Trailing P/E
Forward P/E
-47.85
Rev Growth
+1292.3%
Profit Margin
-96.9%
ROE
-121.1%
Analyst Target
$115.00
Recommendation
STRONG BUY
About Cue Biopharma, Inc.

Cue Biopharma, Inc., a clinical-stage biopharmaceutical company, develops a novel class of injectable therapeutics to selectively engage and modulate targeted, disease relevant T cells in the United States. Its lead drug product candidate is the CUE-401, a bifunctional fusion protein designed to promote immune tolerance by inducing iTregs from Teff cells which is in preclinical trial; and CUE-501, a treatment of autoimmune disease via anti-viral T cell-mediated depletion of B cells. The company also develops CUE-101, which is in phase 1b clinical trial to treat HPV+ recurrent metastatic, or head and neck squamous cell carcinoma in second line, and beyond patients as a monotherapy, as well as in phase 1b clinical trial for the treatment of head and neck squamous cell carcinoma as a first line, therapy in combination with standard of care KEYTRUDA; and CUE-102, which is in phase 1b clinical trial as a monotherapy in late line recurrent metastatic WT1+ colorectal, gastric, ovarian, and pancreatic cancer. It has collaboration agreements with LG Chem, Ltd. for the development of CUE-101 and CUE-102 Immuno-STATs; collaboration and option agreement with Ono Pharmaceutical Co., Ltd to development and commercialization rights for CUE-401; and license agreement with Albert Einstein College of Medicine. The company was formerly known as Imagen Biopharma, Inc. and changed its name to Cue Biopharma, Inc. in October 2016. Cue Biopharma, Inc. was incorporated in 2014 and is headquartered in Boston, Massachusetts.

Opportunity Summary
Passes all ethical screens. Ranks better than 85% of screened stocks.
Ethical Screen
Business ActivityPASS
Debt Ratio (0.04%)PASS
Cash Ratio (0.29%)PASS
Receivables Ratio (0.00%)PASS
Revenue Ratio (0.00%)PASS
OverallPASS
Score Ethical: 87.2
Score Valuation: 33.0
Score Quality: 33.8
Score Combined: 42.1
· Tier: FAIR VALUE

Full Analysis

Opportunity scores, earnings history, insider transactions, institutional holders, analyst consensus, and more.

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Opportunity Scores
Valuation50.0
Quality25.0
Cash Flow50.0
Moat50.0
Balance Sheet100.0
Debt Purity86.7
Liquid Purity10.7
Rev Purity100.0
Compliance68.3
Tier: BRONZE · Score: 49.0 · Rank: #2106
Earnings History (Last 8 Quarters)
DateEPS Est.Reported EPSSurprise %
2026-05-14-3.30-1.08+67.3%
2026-03-16-2.700.30+111.1%
2025-11-12-2.55-2.10+17.6%
2025-08-12-3.90-2.70+30.8%
2025-05-12-4.60-5.10-10.9%
2025-03-31-4.35-3.84+11.7%
2024-11-14-5.70-5.13+10.0%
2024-08-14-8.40-6.00+28.6%
Quarterly Financials
PeriodRevenueNet IncomeEBITDAGross ProfitOp. IncomeEPS
2026-03-31$5.7M-$5.2M-$4.2M-$5.4M-1.08
2025-12-31$21.9M$1.6M$3.3M$2.0M0.30
2025-09-30$2.1M-$7.4M-$6.8M-$7.5M-2.10
2025-06-30$3.0M-$8.5M-$7.6M-$8.6M-2.70
2025-03-31$421.0K-$12.3M-$11.2M-$12.3M-4.95
2024-12-31
Insider Transactions
DateNameRoleSharesValue
2025-12-30SARRAF PASHADirector323,857$99.7K
2024-12-16PASSERI DANIEL RChief Executive Officer30,000$30.9K
Top Institutional Holders
HolderSharesValue% Held
Bleichroeder LP227.3K$4.9M0.1%
GC Wealth Management RIA, LLC154.4K$3.3M0.0%
Vanguard Capital Management LLC81.9K$1.8M0.0%
Lion Point Capital, LP73.4K$1.6M0.0%
Geode Capital Management, LLC35.5K$761.9K0.0%
Vanguard Fiduciary Trust Co18.1K$389.0K0.0%
Robertson Stephens Wealth Management, LLC15.9K$342.4K0.0%
Blackrock Inc.15.0K$321.4K0.0%
Texas Capital Bank Wealth Management Services, Inc.13.2K$284.4K0.0%
Angeles Wealth Management, LLC 10.3K$221.8K0.0%
Analyst Recommendations
3 Months Ago
1
1 analysts
2 Months Ago
1
1 analysts
Last Month
1
1 analysts
Current
1
1 analysts
Strong Buy Buy Hold Sell Strong Sell
Additional Fundamentals
Enterprise Value
$72.9M
Price/Book
3.23
Beta
2.386
Analysts
1
Total Revenue (TTM)
$27.5M
Total Debt
$3.4M
Rec. Mean
1.00
Short Ratio
0.32
Short % Float
0.1%
Employees
29

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Trade Consideration
The Opportunity
Score 42.1 (P50 — top 50.5% of scored tickers). Ethical PASS. 1 analysts at Strong Buy.
Price: $22.97 | Target: $115.00 (+401%)
Score
42
Moat
Conviction
Standard
Upside
+401%
The Fundamentals
Revenue Growth+1292.3%
Profit Margin-96.9%
ROE-121.1%
Forward P/E-47.9
Market Cap$74.8M
Earnings Track Record
DateEstimateReportedSurprise
2026-05-14$-3.30$-1.08+67.3%
2026-03-16$-2.70$0.30+111.1%
2025-11-12$-2.55$-2.10+17.6%
2025-08-12$-3.90$-2.70+30.8%
2025-05-12$-4.60$-5.10-10.9%
2025-03-31$-4.35$-3.84+11.7%
Position Sizing Scenarios
Stop: $19.52 (-15%) | Entry: $22.97
SharesCostProfit to TargetR:R
To Consensus ($115.00, 1 analysts)
10$229.70+$920.30 (401%)26.7R
50$1,148.50+$4,601.50 (401%)26.7R
100$2,297.00+$9,203.00 (401%)26.7R
Risk Factors
  • High beta (2.39) — amplifies market moves by 2.39x
The Verdict
Cue Biopharma, Inc. passes all ethical screens and is growing revenue at +1292.3%.
Quantitative Grade

A single score combining all analytical layers below. A is strongest, D is weakest.

C
Quant Score
49.0
Risk Grade
Layers
8
Quality: HIGH_VOL,CONSISTENT_BEATER
Risk Profile

How much could this ticker lose on a bad day? These metrics measure worst-case scenarios from historical data.

VaR 95%
-11.3%
worst expected daily loss, 19 in 20 days
CVaR 95%
-16.1%
avg loss on the worst 5% of days
Annual Volatility
Sortino Ratio
-0.61
above 1.0 is good
Max Drawdown
-90.5%
Worst Day
Forward Outlook

Based on 10,000 simulated price paths, here is the probability of where this ticker could be in 30, 60, and 90 days.

30d Prob Up
90d Prob Up
Median Return 30d
Liquidity Score
70
Liquidity Grade
LIQUID
Trend & Momentum

What direction is this ticker actually moving, filtered through noise? Is it speeding up or slowing down?

Kalman Trend
Trend Strength
Momentum Signal
HMM Regime
RSI Signal
Technical Signals

Classic chart signals that institutional traders monitor. Golden Cross is bullish, Death Cross is bearish.

MA Crossover
GOLDEN_CROSS
Bollinger Position
LOWER_HALF
Beta
Relative Volume
0.8x
Short Interest
Financial Health

Is this company financially sound? The Z-Score measures bankruptcy risk. The F-Score measures fundamental strength.

Altman Z-Score
below 1.81 = distress zone
Piotroski F-Score
Earnings Beat Rate
87.5%
Earnings Consistency
Correlations

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Seasonality

Does this ticker have consistent patterns on certain days or months? Historical tendencies, not guarantees.

Best Day
Friday
Worst Day
Tuesday
Best Month
Oct
Worst Month
Dec
Fri-Mon Effect
1.126305426517331
Earnings Drift

After this company beats earnings, does the price keep going up? Drift tracks post-earnings momentum.

Avg Drift After Beat
-8.2%
Beat Drift Positive %
16.7%
Consistency
Momentum Rankings

How does this ticker's recent performance compare to the entire universe? Ranked across 1, 3, 6, and 12-month returns.

1M Return
+13.2%
3M Return
+136.8%
6M Return
+23.4%
12M Return
-5.6%
Momentum Rank
#285
Momentum Signal
STRONG_UP

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